[纤维肌痛综合征(FMS)患者体内的四氢大麻酚(THC):关于住院病人跨学科多模式疼痛疗法(IMPT)期间疼痛、心理测量变量和镇痛剂消耗量变化的回顾性研究]。

IF 1.1 4区 医学 Q3 ANESTHESIOLOGY Schmerz Pub Date : 2024-08-01 Epub Date: 2023-06-08 DOI:10.1007/s00482-023-00727-4
Horst Bettstetter, Arne Schäfer
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引用次数: 0

摘要

背景:自 2017 年 3 月 1 日起,医用大麻(MC)可在德国全国范围内处方。迄今为止,已有多项关于医用大麻对纤维肌痛综合征(FMS)疗效的定性研究:该研究旨在调查在跨学科多模式疼痛治疗(IMPT)过程中,四氢大麻酚对疼痛和多个心理测量变量的有效性:在2017-2018年期间,研究人员根据纳入标准选取了一家诊所疼痛病房中所有患有FMS并接受多模式跨学科治疗的患者。按照有THC组和无THC组分别检查了患者的疼痛强度、各种心理测量参数和住院期间的镇痛药消耗量:在纳入研究的 120 名 FMS 患者中,62 名患者(51.7%)接受了 THC 治疗。在疼痛强度、抑郁和生活质量等参数方面,整个组别在住院期间均有显著改善(p 结论:研究结果表明,THC 可以改善 FMS 患者的生活质量:研究结果表明,除了各种指南中推荐的药物外,THC 还可被视为一种医疗替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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[Tetrahydrocannabinol (THC) in patients with fibromyalgia syndrome (FMS) : A retrospective study of changes in pain, psychometric variables, and analgesic consumption during inpatient interdisciplinary multimodal pain therapy (IMPT)].

Background: Since March 1, 2017, medical cannabis (MC) can be prescribed nationwide in Germany. To date, there have been a number of qualitatively different studies on the effectiveness of MC in fibromyalgia syndrome (FMS).

Objective: The aim of the study was to investigate the effectiveness of THC in the course of interdisciplinary multimodal pain therapy (IMPT) on pain and several psychometric variables.

Materials and methods: For the study, in the period 2017-2018, all patients in the pain ward of a clinic who were suffering from FMS and were treated in a multimodal interdisciplinary setting were selected based on inclusion criteria. The patients were examined separately according to groups with and without THC about pain intensity, various psychometric parameters and analgesic consumption during the stay.

Results: Of the 120 FMS patients included in the study, 62 patients (51.7%) were treated with THC. In the parameters of pain intensity, depression, and quality of life, there was a significant improvement in the entire group during the stay (p < 0.001), which was significantly greater through the use of THC. In five of the seven analgesic groups examined, the dose was reduced or the drug discontinued significantly more often in the patients treated with THC.

Conclusion: The results provide indications that THC can be considered as a medical alternative in addition to the substances previously recommended in various guidelines.

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来源期刊
Schmerz
Schmerz 医学-临床神经学
CiteScore
2.00
自引率
20.00%
发文量
64
审稿时长
6-12 weeks
期刊介绍: Der Schmerz is an internationally recognized journal and addresses all scientists, practitioners and psychologists, dealing with the treatment of pain patients or working in pain research. The aim of the journal is to enhance the treatment of pain patients in the long run. Review articles provide an overview on selected topics and offer the reader a summary of current findings from all fields of pain research, pain management and pain symptom management. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Review articles under the rubric ''Continuing Medical Education'' present verified results of scientific research and their integration into daily practice.
期刊最新文献
[Health services research in acute pain medicine : Where do we come from in Germany?] [Surgical treatment of trigeminal pain]. [What is health services research?] [Interdisciplinary multimodal pain therapy: does the dose make a difference? : A comparison from routine clinical care]. [What determines the overall quality of postoperative pain management? A question of perspective].
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