[右髂骨活检诊断前列腺癌1例]。

Masatoshi Konishi, Shu Okamoto, Tetsuya Yamamoto, Tomohiro Kanaki, Jumpei Oshima, Takanori Kinjo, Wataru Nakata, Hiroshi Ohashi, Hitoshi Inoue
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引用次数: 0

摘要

一位73岁男性因前列腺特异抗原(PSA)水平高而转诊至我院。我院PSA水平为63.5 ng/ml。盆腔磁共振成像(MRI)显示强烈提示多发性盆腔骨转移,但前列腺未见明显恶性肿瘤。进行了12芯前列腺活检,未发现癌症。计算机断层扫描和骨显像显示在胸骨、胸腰椎、骨盆骨和骶骨有可疑的骨转移灶。脊柱MRI显示椎体从第八胸椎到第一腰椎有肿块。右髂嵴活检显示腺癌,PSA染色阳性,诊断为前列腺癌多发性骨转移。开始醋酸阿比特龙联合雄激素剥夺。他接受了药物治疗和胸骨放射治疗以缓解疼痛。4个月后脊柱MRI显示椎体重量下降,5个月后血清PSA水平<0.003 ng/ml。治疗17个月后,PSA仍低于0.003 ng/ml,患者目前无痛。
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[A Case of Prostate Cancer Diagnosed by the Bone Biopsy of the Right Iliac Metastatic Lesion].

A 73-year-old man was referred to our hospital because of a high prostate specific antigen (PSA) level. The PSA level at our hospital was 63.5 ng/ml. Pelvic magnetic resonance imaging (MRI) showed findings strongly suggestive of multiple pelvic bone metastases, but no obvious malignant findings in the prostate. A 12-core prostate biopsy was performed and no cancer was detected. Computed tomography and bone scintigraphy showed findings suspicious of bone metastases in the sternum, thoracolumbar spine, pelvic bone, and sacrum. Spine MRI revealed a mass in the vertebral body from the eighth thoracic vertebra to the first lumbar vertebra. A biopsy of the right iliac crest showed adenocarcinoma and was positive for PSA staining, leading to the diagnosis of multiple bone metastases of prostate cancer. Abiraterone acetate in combination with androgen deprivation was started. He received medication and radiation therapy to his sternum for pain relief. Spine MRI after 4 months showed decreased vertebral body weights and serum PSA levels were <0.003 ng/ml after 5 months. Seventeen months after treatment, PSA remains below 0.003 ng/ml, and the patient is currently pain-free.

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来源期刊
Acta Urologica Japonica
Acta Urologica Japonica Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
74
期刊最新文献
[The Case of Solitary Adrenal Metastasis of Urothelial Carcinoma]. [The Introduction of Pubic Hair into the Bladder : A Possibility of an Alternate Mechanism]. [A Case of Metastatic Testicular Cancer after Kidney Transplantation in which Complete Remission was Achieved]. [A Case of Pelvic Arteriovenous Malformation in a Male with Massive Bladder Bleeding which Caused Severe Hemorrhagic Hypovolemic Shock]. [Risk Factor of Cutaneous Symptoms Associated with Enfortumab Vedotin for Urothelial Carcinoma].
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