了解你的微生物敌人:监测在对抗抗菌素耐药性中的作用。

IF 2.5 3区 工程技术 Q2 BIOLOGY Yale Journal of Biology and Medicine Pub Date : 2022-12-01
Rachel E Bosserman, Jennie H Kwon
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引用次数: 0

摘要

抗生素耐药生物(AROs)治疗困难且费用高昂,与高死亡率有关,并且呈上升趋势。在美国,对AROs的追踪有限,这可能有助于传播并抑制感染预防干预。由于缺乏标准化的定植筛查方法和医疗机构之间关于患者aro状态的有限沟通,监测受到限制。对碳青霉烯类耐药肠杆菌(CRE)等广泛耐药AROs已经开展了一些区域监测和报告工作,但需要进一步扩大到全国范围,并包括其他AROs,如广谱β-内酰胺酶(ESBL)产生生物。加强对ARO感染和定植的监测将为未来有针对性的干预和感染预防战略提供信息。
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Know your Microbe Foes: The Role of Surveillance in Combatting Antimicrobial Resistance.

Antibiotic-resistant organisms (AROs) are difficult and costly to treat, associated with high mortality rates, and are on the rise. In the United States, there is limited tracking of AROs, which can contribute to transmission and inhibit infection prevention interventions. Surveillance is limited by a lack of standardized methods for colonization screening and limited communication regarding patient ARO-status between healthcare settings. Some regional surveillance and reporting efforts are in place for extensively-resistant AROs such as carbapenem-resistant Enterobacterales (CRE), but need to be further expanded nationwide and to include other AROs such as extended-spectrum β-lactamase (ESBL) producing organisms. Increased surveillance of ARO infections and colonization will inform future targeted intervention and infection prevention strategies.

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来源期刊
Yale Journal of Biology and Medicine
Yale Journal of Biology and Medicine Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
5.00
自引率
0.00%
发文量
41
期刊介绍: The Yale Journal of Biology and Medicine (YJBM) is a graduate and medical student-run, peer-reviewed, open-access journal dedicated to the publication of original research articles, scientific reviews, articles on medical history, personal perspectives on medicine, policy analyses, case reports, and symposia related to biomedical matters. YJBM is published quarterly and aims to publish articles of interest to both physicians and scientists. YJBM is and has been an internationally distributed journal with a long history of landmark articles. Our contributors feature a notable list of philosophers, statesmen, scientists, and physicians, including Ernst Cassirer, Harvey Cushing, Rene Dubos, Edward Kennedy, Donald Seldin, and Jack Strominger. Our Editorial Board consists of students and faculty members from Yale School of Medicine and Yale University Graduate School of Arts & Sciences. All manuscripts submitted to YJBM are first evaluated on the basis of scientific quality, originality, appropriateness, contribution to the field, and style. Suitable manuscripts are then subject to rigorous, fair, and rapid peer review.
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