D18. MOLECULAR TRAFFIC HUBS IN PULMONARY VASCULAR DISEASE

Small Molecule Readthrough Compound GJ103 Effectively Blocks the Development of Heritable Pulmonary Arterial Hypertension in a Mouse Model

Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6253 Y. Wang, J. Liu, C. Leng, L. Afrose, T. Dao, R. Sakurai, O. Naveed, S. Umar, V. Rehan

Cybrid Analysis Delineates Nuclear and Mitochondrial Contributions to Oxidative Stress in Pulmonary Arterial Hypertension

Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6257 S. Balachandar, T. O’Connell, M. Aldred

Skeletal Muscle SIRT3 Deficiency Remotely Regulates Pulmonary Vascular Remodeling Via LOXL2-CNPY2-p53 Axis in Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction

Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a6256 J.-R. Jheng, Y. Bai, K. Noda, J. Huot, T. Cook, G. Halliday, M. Simon, D. Forman, A. Bonetto, R. Machado, M. Gladwin, Y. Lai