The Lancet

Dual checkpoint blockade for microsatellite instability-high colorectal cancer

Pub Date : 2025-01-25 DOI: 10.1016/s0140-6736(25)00144-8 S Daniel Haldar, Scott Kopetz

Nivolumab plus ipilimumab versus nivolumab in microsatellite instability-high metastatic colorectal cancer (CheckMate 8HW): a randomised, open-label, phase 3 trial

Pub Date : 2025-01-25 DOI: 10.1016/s0140-6736(24)02848-4 Thierry André, Elena Elez, Heinz-Josef Lenz, Lars Henrik Jensen, Yann Touchefeu, Eric Van Cutsem, Rocio Garcia-Carbonero, David Tougeron, Guillermo Ariel Mendez, Michael Schenker, Christelle de la Fouchardiere, Maria Luisa Limon, Takayuki Yoshino, Jin Li, Jose Luis Manzano Mozo, Laetitia Dahan, Giampaolo Tortora, Myriam Chalabi, Eray Goekkurt, Maria Ignez Braghiroli, Sara Lonardi

Wildfires and health: building resilience in Los Angeles’ climate crisis

Pub Date : 2025-01-24 DOI: 10.1016/s0140-6736(25)00129-1 Ying-Ying Goh, Y Tony Yang