Pub Date : 2026-02-09DOI: 10.1016/s0140-6736(25)02474-2
Solja T Nyberg PhD, Philipp Frank PhD, Sara Ahmadi-Abhari MD PhD, Jaana Pentti MSc, Prof Jussi Vahtera MD PhD, Jenni Ervasti PhD, Prof Sakari B Suominen MD PhD, Prof Timo E Strandberg MD PhD, Pyry N Sipilä MD PhD, Prof Seppo Meri MD PhD, Prof Naveed Sattar MD FMedSci, Prof Mika Kivimäki FMedSci
Adult obesity has been linked to specific infections, but evidence across the full spectrum of infectious diseases remains scarce. In this multicohort study with impact modelling, we examined the association between this preventable risk factor and the incidence, hospitalisations, and mortality of 925 bacterial, viral, parasitic, and fungal infectious diseases, and estimated their global and regional attributable impact.
{"title":"Adult obesity and risk of severe infections: a multicohort study with global burden estimates","authors":"Solja T Nyberg PhD, Philipp Frank PhD, Sara Ahmadi-Abhari MD PhD, Jaana Pentti MSc, Prof Jussi Vahtera MD PhD, Jenni Ervasti PhD, Prof Sakari B Suominen MD PhD, Prof Timo E Strandberg MD PhD, Pyry N Sipilä MD PhD, Prof Seppo Meri MD PhD, Prof Naveed Sattar MD FMedSci, Prof Mika Kivimäki FMedSci","doi":"10.1016/s0140-6736(25)02474-2","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02474-2","url":null,"abstract":"Adult obesity has been linked to specific infections, but evidence across the full spectrum of infectious diseases remains scarce. In this multicohort study with impact modelling, we examined the association between this preventable risk factor and the incidence, hospitalisations, and mortality of 925 bacterial, viral, parasitic, and fungal infectious diseases, and estimated their global and regional attributable impact.","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"31 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146146243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1016/s0140-6736(25)02605-4
Thorkild I A Sørensen, Merete Osler
{"title":"Mutually reinforced burdens of obesity and infections","authors":"Thorkild I A Sørensen, Merete Osler","doi":"10.1016/s0140-6736(25)02605-4","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02605-4","url":null,"abstract":"","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146146244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intravenous tenecteplase for acute ischaemic stroke within 24 h due to basilar artery occlusion","authors":"Georgios Tsivgoulis, Lina Palaiodimou, Guillaume Turc","doi":"10.1016/s0140-6736(26)00139-x","DOIUrl":"https://doi.org/10.1016/s0140-6736(26)00139-x","url":null,"abstract":"","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-06DOI: 10.1016/s0140-6736(26)00036-x
Prihatha R Narasimmaraj, Yunzhe Qian, Jose F Figueroa, Sara N Bleich, Rishi K Wadhera
{"title":"Health effects of reductions in food assistance benefits in the USA","authors":"Prihatha R Narasimmaraj, Yunzhe Qian, Jose F Figueroa, Sara N Bleich, Rishi K Wadhera","doi":"10.1016/s0140-6736(26)00036-x","DOIUrl":"https://doi.org/10.1016/s0140-6736(26)00036-x","url":null,"abstract":"","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-06DOI: 10.1016/s0140-6736(26)00219-9
Minghui Ren, Yangmu Huang, Christopher Dowson, Ming Xu, Lewis Husain
{"title":"New approaches for UK–China global health cooperation","authors":"Minghui Ren, Yangmu Huang, Christopher Dowson, Ming Xu, Lewis Husain","doi":"10.1016/s0140-6736(26)00219-9","DOIUrl":"https://doi.org/10.1016/s0140-6736(26)00219-9","url":null,"abstract":"","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-05DOI: 10.1016/s0140-6736(25)02276-7
Mazen Noureddin, Kris V Kowdley, Tatjana Odrljin, Gerard Bain, Jeff Zhao, Brenda Jeglinski, Margaret James Koziel, Rohit Loomba
{"title":"Efimosfermin alfa (BOS-580) once per month in people with metabolic dysfunction-associated steatohepatitis with F2 or F3 fibrosis: results from a 24-week, randomised, double-blind, placebo-controlled, phase 2 trial","authors":"Mazen Noureddin, Kris V Kowdley, Tatjana Odrljin, Gerard Bain, Jeff Zhao, Brenda Jeglinski, Margaret James Koziel, Rohit Loomba","doi":"10.1016/s0140-6736(25)02276-7","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02276-7","url":null,"abstract":"","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"185 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-05DOI: 10.1016/s0140-6736(25)01945-2
Chloe Orkin, Rosie Mngqibisa, Juan Diego Velez, Princy Kumar, Dominique L Braun, Andrew Carr, Mark Bloch, Sharon Walmsley, Pablo Tebas, Yoshiyuki Yokomaku, Tracy L Diamond, Beth Jackson, Karen Eves, Anjana Grandhi, Monica Fuszard, Stephanie O Klopfer, Luisa M Stamm, Michelle C Fox, Jason Kim
{"title":"Switch to fixed-dose doravirine (100 mg) and islatravir (0·25 mg) once daily in virologically suppressed adults with HIV-1 on oral antiretroviral therapy: 48-week results of a phase 3, multicentre, randomised, open-label, non-inferiority trial","authors":"Chloe Orkin, Rosie Mngqibisa, Juan Diego Velez, Princy Kumar, Dominique L Braun, Andrew Carr, Mark Bloch, Sharon Walmsley, Pablo Tebas, Yoshiyuki Yokomaku, Tracy L Diamond, Beth Jackson, Karen Eves, Anjana Grandhi, Monica Fuszard, Stephanie O Klopfer, Luisa M Stamm, Michelle C Fox, Jason Kim","doi":"10.1016/s0140-6736(25)01945-2","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01945-2","url":null,"abstract":"","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-05DOI: 10.1016/s0140-6736(25)01632-0
Teba Alnima, Mark M Smits
No Abstract
没有抽象的
{"title":"Response to STRIDE: semaglutide in peripheral artery disease and type 2 diabetes","authors":"Teba Alnima, Mark M Smits","doi":"10.1016/s0140-6736(25)01632-0","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01632-0","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146129484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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