A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE

Unique Transcriptomic and Metabolic Characteristics of Pulmonary Monocytes and Macrophages in an Inflammatory Rat Model of Pulmonary Arterial Hypertension with Bmpr2Mutations

Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180 L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls

Reciprocal Bi-Directional Cross-Talk Between GATA6 and YAP Regulates Vascular Smooth Muscle Cell Hyper-Proliferation in PAH

Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192 T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova

Effect of Sex Hormones on the Severity of Experimental Pulmonary Hypertension in a Natural Killer Cell-Deficient IL-15 Knockout Rat Model

Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177 L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston