Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180
L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls
{"title":"Unique Transcriptomic and Metabolic Characteristics of Pulmonary Monocytes and Macrophages in an Inflammatory Rat Model of Pulmonary Arterial Hypertension with Bmpr2Mutations","authors":"L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115023691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192
T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova
{"title":"Reciprocal Bi-Directional Cross-Talk Between GATA6 and YAP Regulates Vascular Smooth Muscle Cell Hyper-Proliferation in PAH","authors":"T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130491549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177
L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston
{"title":"Effect of Sex Hormones on the Severity of Experimental Pulmonary Hypertension in a Natural Killer Cell-Deficient IL-15 Knockout Rat Model","authors":"L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122344916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176
V. Lin, D.D. Xing, Y. Wu, S. Hardy, P.R. Cochran, E. Helton, S. Pamboukian, J. Joly, J. Tallaj, G. A. Payne, J. Barnes, J. M. Wells
{"title":"Elucidating the Role of Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in Pulmonary Hypertension","authors":"V. Lin, D.D. Xing, Y. Wu, S. Hardy, P.R. Cochran, E. Helton, S. Pamboukian, J. Joly, J. Tallaj, G. A. Payne, J. Barnes, J. M. Wells","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129111330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178
D. Kim, L. Zhao, T. Wu, R. Vihn, E. Schneider, C. Cunningham, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls
{"title":"Single-Cell RNA-seq Reveals Transcriptionally Convergent Pulmonary Endothelial Cells in an Inflammatory Model of Pulmonary Arterial Hypertension with BMPR2 Dysfunction","authors":"D. Kim, L. Zhao, T. Wu, R. Vihn, E. Schneider, C. Cunningham, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121419908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175
L. Jiang, D. Goncharov, Y. Shen, D. Lin, B. Chang, A. Pena, E. Goncharova, T. Kudryashova
{"title":"SIRT7- and JNK-Mediated Akt Supports Glycolysis-Driven Lipogenesis and Proliferation of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension","authors":"L. Jiang, D. Goncharov, Y. Shen, D. Lin, B. Chang, A. Pena, E. Goncharova, T. Kudryashova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129376621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179
C. Hu, A. Laux, H. Zhang, K. Stenmark
{"title":"ATAC Seq Reveals That Genes Involved in the Persistently Activated Phenotype of PH Fibroblasts Exhibit Open Enhancers and Promoters That Are Enriched in Binding Sites for Several Transcription Factors","authors":"C. Hu, A. Laux, H. Zhang, K. Stenmark","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133007689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183
M. Niihori, J. James, N. McCalin, R.C. Philip, R. Rafikov, O. Rafikova
{"title":"Mitochondrial Dysfunction as a Primary Cause of Impaired Angiogenesis in Pulmonary Arterial Hypertension","authors":"M. Niihori, J. James, N. McCalin, R.C. Philip, R. Rafikov, O. Rafikova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125558454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1186
S. Bousseau, B. Yakubov, E. Sims, M. Repass, A. Frump, T. Lahm
{"title":"Estrogen Stimulates Angiogenesis and Regulates Metabolism in the Right Ventricle and on Cultured Cardiac Microvascular Endothelial Cells","authors":"S. Bousseau, B. Yakubov, E. Sims, M. Repass, A. Frump, T. Lahm","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1186","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1186","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115670990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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