Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180
L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls
{"title":"Unique Transcriptomic and Metabolic Characteristics of Pulmonary Monocytes and Macrophages in an Inflammatory Rat Model of Pulmonary Arterial Hypertension with Bmpr2Mutations","authors":"L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115023691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192
T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova
{"title":"Reciprocal Bi-Directional Cross-Talk Between GATA6 and YAP Regulates Vascular Smooth Muscle Cell Hyper-Proliferation in PAH","authors":"T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130491549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176
V. Lin, D.D. Xing, Y. Wu, S. Hardy, P.R. Cochran, E. Helton, S. Pamboukian, J. Joly, J. Tallaj, G. A. Payne, J. Barnes, J. M. Wells
{"title":"Elucidating the Role of Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in Pulmonary Hypertension","authors":"V. Lin, D.D. Xing, Y. Wu, S. Hardy, P.R. Cochran, E. Helton, S. Pamboukian, J. Joly, J. Tallaj, G. A. Payne, J. Barnes, J. M. Wells","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129111330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177
L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston
{"title":"Effect of Sex Hormones on the Severity of Experimental Pulmonary Hypertension in a Natural Killer Cell-Deficient IL-15 Knockout Rat Model","authors":"L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122344916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178
D. Kim, L. Zhao, T. Wu, R. Vihn, E. Schneider, C. Cunningham, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls
{"title":"Single-Cell RNA-seq Reveals Transcriptionally Convergent Pulmonary Endothelial Cells in an Inflammatory Model of Pulmonary Arterial Hypertension with BMPR2 Dysfunction","authors":"D. Kim, L. Zhao, T. Wu, R. Vihn, E. Schneider, C. Cunningham, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121419908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175
L. Jiang, D. Goncharov, Y. Shen, D. Lin, B. Chang, A. Pena, E. Goncharova, T. Kudryashova
{"title":"SIRT7- and JNK-Mediated Akt Supports Glycolysis-Driven Lipogenesis and Proliferation of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension","authors":"L. Jiang, D. Goncharov, Y. Shen, D. Lin, B. Chang, A. Pena, E. Goncharova, T. Kudryashova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129376621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179
C. Hu, A. Laux, H. Zhang, K. Stenmark
{"title":"ATAC Seq Reveals That Genes Involved in the Persistently Activated Phenotype of PH Fibroblasts Exhibit Open Enhancers and Promoters That Are Enriched in Binding Sites for Several Transcription Factors","authors":"C. Hu, A. Laux, H. Zhang, K. Stenmark","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133007689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183
M. Niihori, J. James, N. McCalin, R.C. Philip, R. Rafikov, O. Rafikova
{"title":"Mitochondrial Dysfunction as a Primary Cause of Impaired Angiogenesis in Pulmonary Arterial Hypertension","authors":"M. Niihori, J. James, N. McCalin, R.C. Philip, R. Rafikov, O. Rafikova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125558454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-01DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1187
M.H. Lee, L. Sanders, R. Kumar, D. Hernández‐Saavedra, X. Yun, J. A. Ford, M. Perez, C. Mickael, A. Gandjeva, D. Koyanagi, J. Harral, David E. Irwin, B. Kassa, R. Eckel, L. Shimoda, B. Graham, R. Tuder
{"title":"The Role of Fatty Acid Oxidation in Animal Models of Pulmonary Hypertension","authors":"M.H. Lee, L. Sanders, R. Kumar, D. Hernández‐Saavedra, X. Yun, J. A. Ford, M. Perez, C. Mickael, A. Gandjeva, D. Koyanagi, J. Harral, David E. Irwin, B. Kassa, R. Eckel, L. Shimoda, B. Graham, R. Tuder","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1187","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1187","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"40 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122921075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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