Frontiers in molecular medicine

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Editorial: Gene therapy and genome editing for metabolic liver disorders.

Pub Date : 2025-01-09 DOI: 10.3389/fmmed.2024.1543685 Fanny Collaud, Giulia Bortolussi

An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells.

Pub Date : 2025-01-08 DOI: 10.3389/fmmed.2024.1492370 Ashley King, Davis Noblitt, Olivia Sherron, Clara Kjerfve, Lydia Pless, Nicholas L Truex

Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model.

Pub Date : 2025-01-06 DOI: 10.3389/fmmed.2024.1487526 Caroline Schoenherr, Stefan Pietzsch, Cristina Barca, Franziska E Müller, Frauke S Bahr, Martina Kasten, Andre Zeug, Sergej Erschow, Christine S Falk, Evgeni Ponimaskin, James T Thackeray, Denise Hilfiker-Kleiner, Melanie Ricke-Hoch

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