Acta Pharmaceutica Sinica B

Intravenous delivery of STING agonists using acid-sensitive polycationic polymer-modified lipid nanoparticles for enhanced tumor immunotherapy

Pub Date : 2024-06-01 DOI: 10.1016/j.apsb.2024.06.004 Ying He, Ke Zheng, Xifeng Qin, Siyu Wang, Xuejing Li, Huiwen Liu, Mingyang Liu, Ruizhe Xu, Shaojun Peng, Zhiqing Pang

Rhizoma Drynariae-derived nanovesicles reverse osteoporosis by potentiating osteogenic differentiation of human bone marrow mesenchymal stem cells via targeting ERα signaling

Pub Date : 2024-02-01 DOI: 10.1016/j.apsb.2024.02.005 Qing Zhao, Junjie Feng, Fubin Liu, Qianxin Liang, Manlin Xie, Jiaming Dong, Yanfang Zou, J. Ye, Guilong Liu, Yue Cao, Zhaodi Guo, Hongzhi Qiao, Lei Zheng, Kewei Zhao

ALS-linked C9orf72 dipeptide repeats inhibit starvation-induced autophagy through modulating BCL2-BECN1 interaction

Pub Date : 2024-02-01 DOI: 10.1016/j.apsb.2024.02.004 Shiqiang Xu, Qilian Ma, Junwen Shen, Ningning Li, Shan Sun, Na-na Wang, Yang Chen, Chunsheng Dong, Kin Yip Tam, Jochen H.M. Prehn, Hongfeng Wang, Zheng Ying