The Impact of Insulin Resistance on Cardiovascular Control During Exercise in Diabetes.

IF 4.9 2区 医学 Q1 PHYSIOLOGY Exercise and Sport Sciences Reviews Pub Date : 2021-07-01 DOI:10.1249/JES.0000000000000259
Masaki Mizuno, Norio Hotta, Rie Ishizawa, Han-Kyul Kim, Gary Iwamoto, Wanpen Vongpatanasin, Jere H Mitchell, Scott A Smith
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引用次数: 4

Abstract

Patients with diabetes display heightened blood pressure response to exercise, but the underlying mechanism remains to be elucidated. There is no direct evidence that insulin resistance (hyperinsulinemia or hyperglycemia) impacts neural cardiovascular control during exercise. We propose a novel paradigm in which hyperinsulinemia or hyperglycemia significantly influences neural regulatory pathways controlling the circulation during exercise in diabetes.

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糖尿病患者运动时胰岛素抵抗对心血管控制的影响
糖尿病患者对运动表现出升高的血压反应,但其潜在机制仍有待阐明。没有直接证据表明胰岛素抵抗(高胰岛素血症或高血糖)会影响运动期间的神经心血管控制。我们提出了一个新的范式,其中高胰岛素血症或高血糖显著影响糖尿病患者运动期间控制循环的神经调节途径。
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来源期刊
Exercise and Sport Sciences Reviews
Exercise and Sport Sciences Reviews 社会科学-生理学
CiteScore
10.70
自引率
1.80%
发文量
72
期刊介绍: Exercise and Sport Sciences Reviews made the transition from an annual hardcover series book to a quarterly journal in January 2000. The mission of this American College of Sports Medicine publication is to provide premier quarterly reviews of the most contemporary scientific, medical, and research-based topics emerging in the field of sports medicine and exercise science. The publication strives to provide the most relevant, topical information to students, professors, clinicians, scientists, and professionals for practical and research applications.
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