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Exercise May Improve Completion of Standard and Emerging Cancer Treatments.
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2025-02-18 DOI: 10.1249/JES.0000000000000360
Ignacio Catalá-Vilaplana, Sabrina E Cao, Kendra Zadravec, Nathalie LeVasseur, Randall J Kimple, Amy J Lim, Kerry S Courneya, Kristin L Campbell

Abstract: Receipt of the entire course of intended anti-cancer treatment is critical to maximize treatment efficacy, reduce risk of disease recurrence, and improve survival. Engaging in an exercise program during cancer treatment has the potential to improve treatment completion, but standardization in terminology for reporting on cancer treatment completion is needed, especially as types of cancer treatments continue to evolve.

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引用次数: 0
Personalized Injury Risk Assessment and Exercise Prescription Based on Tendon Strain.
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2025-02-07 DOI: 10.1249/JES.0000000000000359
Falk Mersmann, Sebastian Bohm, Theresa Domroes, Kolja Weidlich, Adamantios Arampatzis

Abstract: Tendon strain determines the mechanical demand on a tendon and regulates the metabolic and structural response. Imbalances of muscle strength and tendon stiffness can substantially change tendon operating strain, affecting the individual consequences of loading. Such imbalances can be identified based on maximum tendon strain during fixed-end contractions, with implications for a personalized assessment of injury risk and exercise prescription.

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引用次数: 0
Focus on the Forgotten Organelle: Regulation of Lysosomes in Skeletal Muscle. 关注被遗忘的细胞器:骨骼肌溶酶体的调节。
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2025-01-13 DOI: 10.1249/JES.0000000000000358
Neushaw Moradi, Anastasiya Kuznyetsova, Victoria C Sanfrancesco, Sabrina Champsi, David A Hood

Abstract: Research on the role of the lysosome as the terminal organelle in autophagy and in communicating with other organelles in skeletal muscle is in its infancy. We hypothesize that the lysosome can adapt positively to exercise to improve the clearance of cargo, like dysfunctional mitochondria, within muscle, representing an important therapy for protein homeostasis in aging and muscle disuse.

摘要:骨骼肌中溶酶体作为终端细胞器在自噬和与其他细胞器通讯中的作用研究尚处于起步阶段。我们假设溶酶体可以积极适应运动,以改善肌肉内功能失调线粒体等货物的清除,代表了衰老和肌肉废用中蛋白质稳态的重要治疗方法。
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引用次数: 0
Modulation of Vascular Health by Hormonal Contraceptives and Exercise in Young Women: Using the FITT Principles Methodological Framework. 荷尔蒙避孕药和运动对年轻女性血管健康的调节:使用 FITT 原则方法框架。
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-09-27 DOI: 10.1249/JES.0000000000000350
Jenna C Stone, Jennifer S Williams, Maureen J MacDonald

Cardiovascular health is governed by responses of the heart and vasculature to stimuli, including exercise and synthetic hormones in hormonal contraception. In this review, we draw similarities between research examining the effects of exercise training and hormonal contraception on vascular health, aligned using FITT principles (frequency, intensity, type, and time) as a methodological framework, and outline future directions for research.

摘要:心血管健康取决于心脏和血管对刺激的反应,包括运动和激素避孕中的合成激素。在这篇综述中,我们总结了运动训练和激素避孕对血管健康影响的研究之间的相似之处,并将 FITT 原则(频率、强度、类型和时间)作为方法框架进行了统一,同时还概述了未来的研究方向。
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引用次数: 0
Task-Dependent Mechanisms Underlying Prolonged Low-Frequency Force Depression. 长期低频力压抑的任务依赖机制。
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-11-04 DOI: 10.1249/JES.0000000000000352
Andrew J Richards, Daiki Watanabe, Takashi Yamada, Håkan Westerblad, Arthur J Cheng

Prolonged low-frequency force depression (PLFFD) is an intramuscular phenomenon involving the slow recovery of submaximal muscle strength following strenuous exercise. We hypothesize that the contribution of impaired excitation-contraction coupling processes to PLFFD is task dependent, and that they will be different between metabolically and mechanically demanding exercises. We also discuss evidence of the effectiveness of interventions to mitigate PLFFD.

长时间低频力抑制(PLFFD)是一种肌肉内现象,涉及剧烈运动后亚最大肌肉力量的缓慢恢复。我们假设受损的兴奋-收缩耦合过程对PLFFD的贡献是任务依赖的,并且它们在代谢和机械要求的运动中是不同的。我们还讨论了缓解PLFFD干预措施有效性的证据。
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引用次数: 0
Changes In the Brain with An External Focus of Attention: Neural Correlates. 大脑与外部注意力焦点的变化:神经相关。
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2024-12-18 DOI: 10.1249/JES.0000000000000354
Yves-Alain Kuhn, Wolfgang Taube

Abstract: Although it is well established that an external compared to an internal focus of attention enhances motor performance and learning, the underlying neural mechanisms remained relatively underexplored. Recent studies revealed that adopting different attentional strategies results in a differential cortico-motor organization. These findings hold great potential for applying attentional strategies for healthy subjects and populations that display motor deficiencies.

摘要:虽然外部注意力比内部注意力更能提高运动表现和学习能力,但其潜在的神经机制仍未得到充分探讨。最近的研究表明,采用不同的注意策略会导致不同的皮质运动组织。这些发现对于将注意力策略应用于健康受试者和运动缺陷人群具有很大的潜力。
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引用次数: 0
Can Endogenous or Exogenous Ketosis Tackle the Constraints of Ultra-Endurance Exercise? 内源性或外源性酮症能解决超耐力运动的限制吗?
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2024-12-16 DOI: 10.1249/JES.0000000000000357
Louise Engelbrecht, Elmarie Terblanche, Katrien Koppo, Chiel Poffé

Abstract: A high-fat, low-carbohydrate, ketogenic diet has already appealed to athletes for a long time due to its purported ability to improve exercise performance and post-exercise recovery. The availability of ketone supplements has further sparked such interest. The review therefore focuses on the potential beneficial impact of exogenous and endogenous ketosis in the context of ultra-endurance exercise.

摘要:长期以来,高脂肪、低碳水化合物、生酮饮食已经吸引了运动员,因为它据称能够提高运动表现和运动后恢复。酮类补充剂的可用性进一步激发了这种兴趣。因此,本文将重点讨论外源性和内源性酮症在超耐力运动中的潜在有益影响。
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引用次数: 0
Gamified Mobile Health Strategies for Promoting Physical Activity in Autistic Adults. 促进自闭症成人体育活动的游戏化移动健康策略
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2024-12-10 DOI: 10.1249/JES.0000000000000353
Daehyoung Lee, Georgia C Frey, Patrick C Shih

Abstract: Physical inactivity and sedentarism among autistic adults are a growing public health concern. Focusing on the integration of behavior change theories and emphasizing the unique preference for visuospatial learning and gaming technology, we hypothesize that gamified mobile health (mHealth) applications can be effective at increasing free-living physical activity and reducing sedentary behavior in autistic adults.

成人自闭症患者缺乏运动和久坐是一个日益受到关注的公共卫生问题。关注行为改变理论的整合,并强调视觉空间学习和游戏技术的独特偏好,我们假设游戏化移动健康(mHealth)应用程序可以有效地增加自闭症成年人的自由生活身体活动和减少久坐行为。
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引用次数: 0
Hormones, Hypertrophy, and Hype: An Evidence-Guided Primer on Endogenous Endocrine Influences on Exercise-Induced Muscle Hypertrophy. 激素、肥大和炒作:内源性内分泌对运动诱发肌肉肥大影响的证据指导入门》。
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2024-10-01 Epub Date: 2024-08-01 DOI: 10.1249/JES.0000000000000346
Derrick W Van Every, Alysha C D'Souza, Stuart M Phillips

We review the evidence indicating that endogenous changes in these hormones, including testosterone, growth hormone, insulin growth factor-1, and estrogen, and their proposed anabolic effects contribute to and augment resistance exercise training (RET)-induced hypertrophy. Additionally, we provide recommendations for gold-standard methodological rigor to establish best practices for verifying menstrual phases as part of their research, ultimately enhancing our understanding of the impact of ovarian hormones on RET-induced adaptations.

摘要:我们回顾了表明这些激素(包括睾酮、生长激素、胰岛素生长因子-1 和雌激素)的内源性变化及其拟合成代谢作用有助于并增强阻力运动训练(RET)诱导的肥大的证据。此外,我们还就黄金标准方法论的严谨性提出了建议,以建立作为研究一部分的验证月经期的最佳实践,最终提高我们对卵巢激素对 RET 诱导的适应性影响的认识。
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引用次数: 0
A Compensatory Role of Physical Activity in the Association Between Sleep and Cognition. 体育锻炼在睡眠与认知之间的联系中的补偿作用
IF 4.9 2区 医学 Q1 PHYSIOLOGY Pub Date : 2024-10-01 Epub Date: 2024-08-01 DOI: 10.1249/JES.0000000000000345
Kelsey R Sewell, Audrey M Collins, Maddison L Mellow, Ryan S Falck, Belinda M Brown, Ashleigh E Smith, Kirk I Erickson

We synthesize evidence investigating the hypothesis that greater engagement in physical activity (PA) may compensate for some of the negative cognitive consequences associated with poor sleep in older adults. Potential mechanistic pathways include glymphatic clearance, influences on depression, and other comorbidities. The evidence base is largely cross-sectional and observational, and further experimental studies are required.

摘要:我们综述了一些证据,这些证据调查了这样一个假设,即更多地参与体育活动(PA)可以弥补老年人因睡眠不足而产生的一些负面认知后果。潜在的机理途径包括甘油清除、对抑郁症的影响以及其他合并症。证据基础主要是横断面和观察性的,还需要进一步的实验研究。
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引用次数: 0
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Exercise and Sport Sciences Reviews
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