Novel Therapeutic Strategies in Heart Failure in Adult Congenital Heart Disease: of Medicines and Devices.

IF 3.8 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Current Heart Failure Reports Pub Date : 2023-10-01 Epub Date: 2023-08-16 DOI:10.1007/s11897-023-00621-1

Sumeet Vaikunth, Swethika Sundaravel, Joshua Saef, Juan Ortega-Legaspi

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引用次数: 1

Abstract

Purpose of review: This paper reviews the latest literature on the growing field of heart failure in the adult congenital heart disease population.

Recent findings: After highlighting the increasing prevalence and a few of the unique potential causes, including the concept of early senescence, this review begins with novel medical management strategies such as the angiotensin II receptor blocker and neprilysin inhibitors and sodium glucose cotransporter-2 inhibitors. Then, it addresses the latest applications of percutaneous techniques like implantable hemodynamic monitoring, transcatheter pulmonary and aortic valve replacement, and mitral clips. Cardiac resynchronization therapy and novel lymphatic system imaging and intervention are then described. Finally, the use of mechanical support devices, temporary and durable, is discussed as well as heart and combined heart and liver transplantation. There have been recent exciting advances in the strategies used to manage adult congenital heart disease patients with heart failure. As this population continues to grow, it is likely we will see further rapid evolution in this field.

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成人先天性心脏病心力衰竭的新治疗策略：药物和器械。

综述目的：本文综述了成人先天性心脏病人群心力衰竭增长领域的最新文献。最近的发现：在强调了发病率的增加和一些独特的潜在原因（包括早衰的概念）后，这篇综述从新的医疗管理策略开始，如血管紧张素II受体阻滞剂和奈普赖氨酸抑制剂以及钠-葡萄糖协同转运蛋白-2抑制剂。然后，它介绍了经皮技术的最新应用，如植入式血液动力学监测、经导管肺动脉瓣和主动脉瓣置换术以及二尖瓣夹。然后介绍了心脏再同步治疗和新型淋巴系统成像和干预。最后，讨论了临时和耐用的机械支撑装置的使用，以及心脏移植和心肝联合移植。在用于管理患有心力衰竭的成人先天性心脏病患者的策略方面，最近取得了令人兴奋的进展。随着人口的持续增长，我们很可能会看到这一领域的进一步快速发展。

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来源期刊

Current Heart Failure Reports Medicine-Emergency Medicine

CiteScore

5.30

自引率

0.00%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of heart failure. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as investigative, pharmacologic, and nonpharmacologic therapies, pathophysiology, and prevention. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.

期刊最新文献

Cardiogenic Shock: Focus on Non-Cardiac Biomarkers. Biomarkers of Hemodynamic Congestion in Heart Failure. Heart Failure in Rheumatoid Arthritis: Clinical Implications. Screening for Heart Failure: Biomarkers to Detect Heightened Risk in the General Population. Troponin Elevation in Asymptomatic Cancer Patients: Unveiling Connections and Clinical Implications.