A Review of the Scoring and Assessment of Keratosis Pilaris.

IF 1.4 Q3 DERMATOLOGY Skin Appendage Disorders Pub Date : 2023-08-01 Epub Date: 2023-04-20 DOI:10.1159/000529487
Madeline A Wang, Anna Wilson, Dédée F Murrell
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引用次数: 0

Abstract

Disease severity assessment tools play a large part in evaluating skin conditions in dermatology. Currently, there is no existing validated assessment tool for keratosis pilaris (KP), a benign yet highly prevalent follicular disorder. A range of proposed scoring tools have been used in different clinical trials for the assessment of potential treatments for KP. A literature review of the current scoring systems used for KP shows that there is a lack of consistency with most studies using varying versions of unvalidated investigator global assessment (IGA) scores and quartile grading systems. A review of these studies shows that current methods of evaluating KP in clinical trials are subjective, unreliable, and inconsistent. A standardised and validated scoring system would be significant as it could be used in clinical trials to advance the current knowledge of KP.

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角化病评分和评估综述。
疾病严重程度评估工具在皮肤病学的皮肤状况评估中发挥着重要作用。毛囊角化症(KP)是一种良性但发病率很高的毛囊性疾病,目前还没有经过验证的评估工具。在不同的临床试验中,已经使用了一系列建议的评分工具来评估 KP 的潜在治疗方法。对目前用于 KP 的评分系统进行的文献综述显示,大多数研究使用不同版本的未经验证的研究者总体评估 (IGA) 评分和四分法分级系统,缺乏一致性。对这些研究的回顾表明,目前在临床试验中评估 KP 的方法是主观、不可靠和不一致的。标准化和经过验证的评分系统将具有重要意义,因为它可用于临床试验,以增进目前对 KP 的了解。
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来源期刊
CiteScore
2.00
自引率
10.00%
发文量
69
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