[Transcatheter aortic-valve implantation. A ten years clinical experience].

IF 0.5 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Revista medica de Chile Pub Date : 2022-11-01 DOI:10.4067/S0034-98872022001101422
Gonzalo Martínez, Alberto Fuensalida, Pablo Sepúlveda, Juan Francisco Bulnes, Jorge Quitral, Francisco Pacheco, Edith Valenzuela, Rosa Lazen, Alejandra Flores, Ricardo Zalaquett, Alejandro Martínez
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Abstract

Background: Transcatheter aortic-valve implantation (TAVI) was introduced in 2002 and the first implants in our country were performed in 2010.

Aim: To review the TAVI experience in our hospital, considering the technology improvements and gained experience throughout this period.

Material and methods: All patients undergoing TAVI in our center were included. Results and complications were adjudicated according to the Valve Academic Research Consortium-2 (VARC-2) criteria. Patients were divided in 3 groups, according to procedural year: Period 1: 2010-2015 (n = 35); Period 2: 2016-2018 (n = 35); Period 3: 2019-2021 (n = 41). Mortality up to one year after the procedure was recorded.

Results: Between 2010 and 2021, 111 TAVI procedures were performed. The mean age of patients was 82 years and 47% were women. Risk scores for in-hospital mortality were STS 6.7%, EUROSCORE II 8.0% and ACC/STS TAVR Score 4.9%. The trans-femoral route was used in 88% and a balloon-expandable valve was chosen in 82% of patients. A successful implant was achieved in 96%, with an in-hospital mortality of 1.8%. Mortality at 30 days and 1-year were 2.7 and 9.0%, respectively. During period 3, 100% of implants were successful, with no in-hospital mortality, less vascular complications (p < 0.01), less stroke (p = 0.04), less severe paravalvular leak (p = 0.01) and significantly lower rate of acute complications (p < 0.01).

Conclusions: TAVI achieves excellent results. With greater experience and better available technologies, these results are even more favorable.

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经导管主动脉瓣植入术。有十年的临床经验。
背景:经导管主动脉瓣植入术(Transcatheter主动脉瓣植入术,TAVI)于2002年引进,2010年在我国进行了第一例植入术。目的:总结我院TAVI的经验,结合技术进步和经验总结。材料和方法:纳入本中心所有接受TAVI的患者。结果和并发症根据瓣膜学术研究联盟-2 (VARC-2)标准进行判定。根据手术年份将患者分为3组:第一阶段:2010-2015年(n = 35);第二阶段:2016-2018年(n = 35);第三阶段:2019-2021 (n = 41)。记录手术后一年内的死亡率。结果:2010年至2021年间,111例TAVI手术。患者的平均年龄为82岁,其中47%为女性。住院死亡率风险评分为STS 6.7%, EUROSCORE II为8.0%,ACC/STS TAVR评分为4.9%。88%的患者采用经股动脉途径,82%的患者选择球囊可膨胀瓣膜。植入成功率96%,住院死亡率1.8%。30天死亡率为2.7%,1年死亡率为9.0%。第3期植入成功率100%,无院内死亡,血管并发症少(p < 0.01),卒中少(p = 0.04),严重瓣旁漏少(p = 0.01),急性并发症发生率明显降低(p < 0.01)。结论:TAVI效果良好。有了更多的经验和更好的可用技术,这些结果甚至更有利。
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来源期刊
Revista medica de Chile
Revista medica de Chile 医学-医学:内科
CiteScore
1.20
自引率
16.70%
发文量
75
审稿时长
3-6 weeks
期刊介绍: La Revista Médica de Chile publica trabajos originales sobre temas de interés médico y de Ciencias Biomédicas, dando preferencia a los relacionados con la Medicina Interna y sus especialidades derivadas. Publicada mensualmente, desde 1872, por la Sociedad Médica de Santiago. La abreviatura de su título es Rev Med Chile, que debe ser usado en bibliografías, notas al pié de página, leyendas y referencias bibliográficas.
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