Quality of hematology and clinical chemistry results in laboratory and zoo nonhuman primates: Effects of the preanalytical phase. A review

IF 0.8 4区 农林科学 Q3 VETERINARY SCIENCES Journal of Medical Primatology Pub Date : 2023-08-23 DOI:10.1111/jmp.12666
Fanny A. Granat, Catherine Trumel, Jean-Pierre D. Braun, Nathalie H. Bourgès-Abella
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Abstract

Most errors in clinical pathology originate in the preanalytical phase, which includes all steps from the preparation of animals and equipment to the collection of the specimen and its management until analyzed. Blood is the most common specimen collected in nonhuman primates. Other specimens collected include urine, saliva, feces, and hair. The primary concern is the variability of blood hematology and biochemistry results due to sampling conditions with the effects of capture, restraint, and/or anesthesia. Housing and diet have fewer effects, with the exception of food restriction to reduce obesity. There has been less investigation regarding the impact of sampling conditions of nonblood specimens.

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实验室和动物园非人灵长类动物血液学和临床化学结果的质量:分析前阶段的影响。复习一下。
临床病理学中的大多数错误起源于分析前阶段,包括从动物和设备的准备到标本的收集及其管理直到分析的所有步骤。血液是非人类灵长类动物中最常见的标本。收集的其他标本包括尿液、唾液、粪便和毛发。主要关注的是血液血液学和生物化学结果的可变性,这是由于采样条件与捕获、约束和/或麻醉的影响。除了限制食物以减少肥胖外,住房和饮食的影响较小。关于非血液标本取样条件影响的研究较少。
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来源期刊
CiteScore
1.40
自引率
42.90%
发文量
62
审稿时长
6 months
期刊介绍: The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs. Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.
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