{"title":"Effect of smoking on corneal and lens clarity: a densitometric analysis.","authors":"Delil Özcan","doi":"10.1080/15569527.2023.2234023","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To assess the effect of chronic cigarette smoking on corneal and lens densitometry measurements using Pentacam HR and to compare the results obtained with those in non-smokers.</p><p><strong>Materials and methods: </strong>This cross-sectional comparative study included 40 chronic-smokers and 40 age-matched healthy non-smokers between 18-40 years. After general ophthalmic examination, the Pentacam HR imaging system was used to evaluate corneal and lens densitometry measurements of smokers and non-smokers.</p><p><strong>Results: </strong>The mean corneal densitometry values were not statistically significantly different in all the concentric zones and layers in the eyes of the smokers and non-smokers (<i>p</i> > 0.05, for all). However, the mean values of zone 1, zone 2, zone 3 and average lens densitometry measurements of the smokers were statistically significantly higher compared to non-smokers (<i>p</i> < 0.05, for all). Additionally, significant positive correlations were detected between the number of pack-years smoked and lens densitometry measurements.</p><p><strong>Conclusion: </strong>Lens densitometry measurements of smokers were significantly increased while corneal densitometry measurements were not significantly altered compared to non-smokers. Smoking may contribute to cataractogenesis and smoking and age-related changes may act synergistically to cataract development among smokers.</p>","PeriodicalId":11023,"journal":{"name":"Cutaneous and Ocular Toxicology","volume":" ","pages":"198-203"},"PeriodicalIF":1.6000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cutaneous and Ocular Toxicology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/15569527.2023.2234023","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/13 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To assess the effect of chronic cigarette smoking on corneal and lens densitometry measurements using Pentacam HR and to compare the results obtained with those in non-smokers.
Materials and methods: This cross-sectional comparative study included 40 chronic-smokers and 40 age-matched healthy non-smokers between 18-40 years. After general ophthalmic examination, the Pentacam HR imaging system was used to evaluate corneal and lens densitometry measurements of smokers and non-smokers.
Results: The mean corneal densitometry values were not statistically significantly different in all the concentric zones and layers in the eyes of the smokers and non-smokers (p > 0.05, for all). However, the mean values of zone 1, zone 2, zone 3 and average lens densitometry measurements of the smokers were statistically significantly higher compared to non-smokers (p < 0.05, for all). Additionally, significant positive correlations were detected between the number of pack-years smoked and lens densitometry measurements.
Conclusion: Lens densitometry measurements of smokers were significantly increased while corneal densitometry measurements were not significantly altered compared to non-smokers. Smoking may contribute to cataractogenesis and smoking and age-related changes may act synergistically to cataract development among smokers.
期刊介绍：
Cutaneous and Ocular Toxicology is an international, peer-reviewed journal that covers all types of harm to cutaneous and ocular systems. Areas of particular interest include pharmaceutical and medical products; consumer, personal care, and household products; and issues in environmental and occupational exposures.
In addition to original research papers, reviews and short communications are invited, as well as concise, relevant, and critical reviews of topics of contemporary significance.
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