Association between serum vitamin C and chronic kidney disease among adults in NHANES, 2017-2018.

IF 2.6 4区医学 Q1 MEDICINE, GENERAL & INTERNAL Postgraduate Medicine Pub Date : 2023-09-01 Epub Date: 2023-09-07 DOI:10.1080/00325481.2023.2255121

Minhua Li

{"title":"Association between serum vitamin C and chronic kidney disease among adults in NHANES, 2017-2018.","authors":"Minhua Li","doi":"10.1080/00325481.2023.2255121","DOIUrl":null,"url":null,"abstract":"Objective: The current study evaluated the relationship between serum vitamin C and chronic kidney disease.Methods: The database from the National Health and Nutrition Examination Survey (NHANES, 2017-2018) was used to perform a cross-sectional study. Multivariate logistic regression was performed to analyze the relationship between serum vitamin C and chronic kidney disease (CKD), and stratified analysis by sex was performed to assess whether there were sex differences in the association between serum vitamin C and CKD.Results: Before stratified analysis, multivariate logistic regression showed that serum vitamin C was negatively associated with CKD in all models (All OR > 1, P< 0.05), the risk of CKD decreased by one quantile increase in serum vitamin C (P for trend< 0.001) and low vitamin C status was associated with a higher risk of CKD (All OR > 1, P< 0.05). Stratified analyses by sex showed that the association between serum vitamin C and CKD remained negative in men, but not in women.Conclusion: There were a negative correlation between serum vitamin C and CKD, low levels of vitamin C were associated with a higher risk of CKD, and these associations were only found in men, but not in women.","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":" ","pages":"701-707"},"PeriodicalIF":2.6000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Postgraduate Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00325481.2023.2255121","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/9/7 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: The current study evaluated the relationship between serum vitamin C and chronic kidney disease.

Methods: The database from the National Health and Nutrition Examination Survey (NHANES, 2017-2018) was used to perform a cross-sectional study. Multivariate logistic regression was performed to analyze the relationship between serum vitamin C and chronic kidney disease (CKD), and stratified analysis by sex was performed to assess whether there were sex differences in the association between serum vitamin C and CKD.

Results: Before stratified analysis, multivariate logistic regression showed that serum vitamin C was negatively associated with CKD in all models (All OR > 1, P< 0.05), the risk of CKD decreased by one quantile increase in serum vitamin C (P for trend< 0.001) and low vitamin C status was associated with a higher risk of CKD (All OR > 1, P< 0.05). Stratified analyses by sex showed that the association between serum vitamin C and CKD remained negative in men, but not in women.

Conclusion: There were a negative correlation between serum vitamin C and CKD, low levels of vitamin C were associated with a higher risk of CKD, and these associations were only found in men, but not in women.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

2017-2018年NHANES成年人血清维生素C与慢性肾脏疾病的关系。

目的：探讨血清维生素C与慢性肾脏疾病的关系。方法：使用国家健康和营养检查调查（NHANES，2017-2018）的数据库进行横断面研究。采用多因素logistic回归分析血清维生素C与慢性肾脏疾病（CKD）的关系，并按性别进行分层分析，评估血清维生素C和CKD之间的相关性是否存在性别差异，多变量逻辑回归显示，在所有模型中，血清维生素C与CKD呈负相关（所有OR > 1，P 1，P结论：血清维生素C与CKD呈负相关，维生素C水平低与CKD风险高有关，这些相关性仅在男性中发现，而在女性中没有发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Postgraduate Medicine 医学-医学：内科

CiteScore

6.10

自引率

2.40%

发文量

110

审稿时长

6-12 weeks

期刊介绍： Postgraduate Medicine is a rapid peer-reviewed medical journal published for physicians. Tracing its roots back to 1916, Postgraduate Medicine was established by Charles Mayo, MD, as a peer-to-peer method of communicating the latest research to aid physicians when making treatment decisions, and it maintains that aim to this day. In addition to its core subscriber base, Postgraduate Medicine is distributed to hundreds of US-based physicians within internal medicine and family practice.