Recent Advances in MXene Quantum Dots: A Platform with Unique Properties for General-Purpose Functional Materials with Novel Biomedical Applications

IF 8.6 2区 化学 Q1 Chemistry Topics in Current Chemistry Pub Date : 2023-09-05 DOI:10.1007/s41061-023-00439-4
Elham Einafshar, Nafiseh Einafshar, Majid Khazaei
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引用次数: 2

Abstract

Developing new, high-performance materials is a prerequisite for technological advancement. In comparison to bulk materials, quantum dots have a number of good advantages due to their small size, high surface area, and quantum dimensions. Quantum dots, two-dimensional materials with lateral dimensions less than 100 nm, can be generated by the quantum confinement effect. Mxene quantum dots (MQDs) retain some of their two-dimensional characteristics. They also exhibit novel physicochemical properties, including enhanced dispersibility in aqueous and nonaqueous phases, modification or doping capabilities, and photoluminescence. MQDs, due to their unique and diverse properties, have been receiving a great deal of attention as new members of the Mxene group and wide use for biotechnology, bioimaging, optoelectronics, catalysis, cancer therapy, etc. This review aims to provide an overview of the synthesis of MQDs, their optical properties, and their cancer therapy applications. MQDs exhibit remarkable photothermal and photodynamic features and can be suitable for bioimaging. In addition to obtaining bioimaging, photothermal therapy (PTT) and photodynamic therapy (PDT) effects simultaneously, MQDs have high biocompatibility in vitro and in vivo, providing evidence of their potential clinical utility. Herein, recent developments and future prospects concerning MQDs biomedical applications are discussed.

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MXene量子点的最新进展:一种具有独特性能的平台,用于具有新型生物医学应用的通用功能材料。
开发新的高性能材料是技术进步的先决条件。与大块材料相比,量子点由于其小尺寸、高表面积和量子尺寸而具有许多良好的优势。量子点是横向尺寸小于100nm的二维材料,可以通过量子约束效应产生。Mxene量子点(MQD)保留了它们的一些二维特性。它们还表现出新的物理化学性质,包括在水相和非水相中增强的分散性、改性或掺杂能力以及光致发光。MQD由于其独特和多样的性质,作为Mxene组的新成员,以及在生物技术、生物成像、光电子、催化、癌症治疗等方面的广泛应用,受到了广泛的关注。本综述旨在概述MQD的合成、其光学性质及其癌症治疗应用。MQD表现出显著的光热和光动力特性,可适用于生物成像。除了同时获得生物成像、光热治疗(PTT)和光动力治疗(PDT)效果外,MQD在体外和体内都具有高度的生物相容性,为其潜在的临床应用提供了证据。本文讨论了MQDs生物医学应用的最新进展和未来前景。
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来源期刊
Topics in Current Chemistry
Topics in Current Chemistry 化学-化学综合
CiteScore
11.70
自引率
1.20%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Topics in Current Chemistry provides in-depth analyses and forward-thinking perspectives on the latest advancements in chemical research. This renowned journal encompasses various domains within chemical science and their intersections with biology, medicine, physics, and materials science. Each collection within the journal aims to offer a comprehensive understanding, accessible to both academic and industrial readers, of emerging research in an area that captivates a broader scientific community. In essence, Topics in Current Chemistry illuminates cutting-edge chemical research, fosters interdisciplinary collaboration, and facilitates knowledge-sharing among diverse scientific audiences.
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