The role of PET/CT in disease activity assessment in patients with large vessel vasculitis.

IF 5.2 2区医学 Q1 RHEUMATOLOGY Current opinion in rheumatology Pub Date : 2023-05-01 DOI:10.1097/BOR.0000000000000931

Elena Galli, Nicolò Pipitone, Carlo Salvarani

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Abstract

Purpose of review: The aim of this article was to review the recent contributions on the role of PET in assessing disease activity in patients with large-vessel vasculitis (giant cell arteritis and Takayasu arteritis).

Recent findings: 18 FDG (fluorodeoxyglucose) vascular uptake in large-vessel vasculitis at PET shows moderate correlation with clinical indices, laboratory markers and signs of arterial involvement at morphological imaging. Limited data may suggest that 18 FDG (fluorodeoxyglucose) vascular uptake could predict relapses and (in Takayasu arteritis) the development of new angiographic vascular lesions. PET appears to be in general sensitive to change after treatment.

Summary: While the role of PET in diagnosis large-vessel vasculitis is established, its role in evaluating disease activity is less clear-cut. PET may be used as an ancillary technique, but a comprehensive assessment, including clinical, laboratory and morphological imaging is still required to monitor patients with large-vessel vasculitis over time.

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PET/CT在大血管炎患者疾病活动性评估中的作用

综述目的:本文的目的是回顾PET在评估大血管炎(巨细胞动脉炎和高松动脉炎)患者疾病活动性方面的最新进展。最近的发现:PET显示大血管炎中FDG(氟脱氧葡萄糖)血管摄取与临床指标、实验室标志物和形态学成像中动脉受累的迹象中度相关。有限的数据可能表明18 FDG(氟脱氧葡萄糖)血管摄取可以预测复发和(在高松动脉炎中)新的血管造影病变的发展。PET似乎对治疗后的变化很敏感。摘要:虽然PET在诊断大血管炎中的作用已经确立，但其在评估疾病活动性方面的作用尚不明确。PET可作为一种辅助技术，但仍需要综合评估，包括临床、实验室和形态学成像，以长期监测大血管炎患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in rheumatology 医学-风湿病学

CiteScore

9.70

自引率

2.00%

发文量

审稿时长

6-12 weeks

期刊介绍： A high impact review journal which boasts an international readership, Current Opinion in Rheumatology offers a broad-based perspective on the most recent and exciting developments within the field of rheumatology. Published bimonthly, each issue features insightful editorials and high quality invited reviews covering two or three key disciplines which include vasculitis syndromes, medical physiology and rheumatic diseases, crystal deposition diseases and rheumatoid arthritis. Each discipline introduces world renowned guest editors to ensure the journal is at the forefront of knowledge development and delivers balanced, expert assessments of advances from the previous year.

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