The 2023 Impact of Inflammatory Bowel Disease in Canada: Direct Health System and Medication Costs.

M Ellen Kuenzig, Stephanie Coward, Laura E Targownik, Sanjay K Murthy, Eric I Benchimol, Joseph W Windsor, Charles N Bernstein, Alain Bitton, Jennifer L Jones, Kate Lee, Juan-Nicolás Peña-Sánchez, Noelle Rohatinsky, Sara Ghandeharian, James H B Im, Rohit Jogendran, Saketh Meka, Jake Weinstein, Tyrel Jones May, Manisha Jogendran, Sahar Tabatabavakili, Elias Hazan, Malini Hu, Jessica Amankwah Osei, Rabia Khan, Grace Wang, Mira Browne, Tal Davis, Quinn Goddard, Julia Gorospe, Kate Latos, Kate Mason, Jack Kerr, Naji Balche, Anna Sklar, Gilaad G Kaplan
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Abstract

Healthcare utilization among people living with inflammatory bowel disease (IBD) in Canada has shifted from inpatient management to outpatient management; fewer people with IBD are admitted to hospitals or undergo surgery, but outpatient visits have become more frequent. Although the frequency of emergency department (ED) visits among adults and seniors with IBD decreased, the frequency of ED visits among children with IBD increased. Additionally, there is variation in the utilization of IBD health services within and between provinces and across ethnocultural and sociodemographic groups. For example, First Nations individuals with IBD are more likely to be hospitalized than the general IBD population. South Asian children with Crohn's disease are hospitalized more often than their Caucasian peers at diagnosis, but not during follow-up. Immigrants to Canada who develop IBD have higher health services utilization, but a lower risk of surgery compared to individuals born in Canada. The total direct healthcare costs of IBD, including the cost of hospitalizations, ED visits, outpatient visits, endoscopy, cross-sectional imaging, and medications are rising rapidly. The direct health system and medication costs of IBD in Canada are estimated to be $3.33 billion in 2023, potentially ranging from $2.19 billion to $4.47 billion. This is an increase from an estimated $1.28 billion in 2018, likely due to sharp increases in the use of biologic therapy over the past two decades. In 2017, 50% of total direct healthcare costs can be attributed to biologic therapies; the proportion of total direct healthcare costs attributed to biologic therapies today is likely even greater.

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2023年加拿大炎症性肠病的影响:直接卫生系统和药物费用
加拿大炎症性肠病(IBD)患者的医疗保健利用已从住院管理转向门诊管理;IBD患者入院或接受手术的人数减少,但门诊就诊却越来越频繁。尽管成人和老年IBD患者急诊科(ED)就诊频率下降,但IBD儿童患者急诊科就诊频率上升。此外,在各省内部和各省之间以及不同民族文化和社会人口群体之间,利用IBD保健服务的情况也存在差异。例如,第一民族患有IBD的个体比一般IBD人群更有可能住院。患有克罗恩病的南亚儿童在诊断时比他们的白种人同龄人更常住院,但在随访期间则不然。与加拿大出生的人相比,加拿大移民患IBD的人有更高的医疗服务利用率,但手术风险较低。IBD的总直接医疗费用,包括住院费用、急诊科就诊费用、门诊就诊费用、内窥镜检查费用、横断面成像费用和药物费用正在迅速上升。到2023年,加拿大IBD的直接卫生系统和药物费用估计为33.3亿美元,可能从21.9亿美元到44.7亿美元不等。这比2018年估计的12.8亿美元有所增加,可能是由于过去20年生物疗法的使用急剧增加。2017年,50%的直接医疗费用可归因于生物疗法;目前,生物疗法在直接医疗费用总额中所占的比例可能更大。
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