Management of coronavirus disease 2019 vaccine-induced cutaneous complications: A comprehensive literature review.

IF 1.9 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Family and Community Medicine Pub Date : 2023-07-01 Epub Date: 2023-07-24 DOI:10.4103/jfcm.jfcm_3_23
Nouf F Bin Rubaian, Abdullah A Aljalfan, Serene R Almuhaidib
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引用次数: 1

Abstract

Despite the numerous reports of cutaneous manifestations associated with vaccines for coronavirus disease 2019 (COVID-19), the relationship between COVID-19 vaccines and cutaneous side effects remains unevaluated. In this review, we examine these manifestations and their management. Reported dermatoses included injection-site reaction (early and delayed), type I allergic reaction, morbilliform eruption, pityriasis rosea, Sweet syndrome, lichen planus, psoriasis, herpes zoster reactivation, erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis (TEN). The most common COVID-19 vaccination-related cutaneous manifestations are delayed local reactions, approximately 66% of which are associated with the Moderna vaccine, and 33% with the Pfizer vaccine. Aside from mild injection-site reactions, severe reactions include anaphylaxis and TEN. Most reactions, except for Stevens-Johnson syndrome and anaphylaxis, though unpredictable and unpreventable are mild and can be treated symptomatically. Findings from this review should allow primary care physicians and dermatologists to reach faster diagnosis and initiate prompt intervention.

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2019冠状病毒病疫苗引起的皮肤并发症的管理:一项全面的文献综述。
尽管有大量与2019冠状病毒病(新冠肺炎)疫苗相关的皮肤表现报告,但新冠肺炎疫苗与皮肤副作用之间的关系仍未得到评估。在这篇综述中,我们研究了这些表现及其管理。报告的皮肤病包括注射部位反应(早期和延迟)、I型过敏反应、麻疹样皮疹、玫瑰糠疹、Sweet综合征、扁平苔藓、银屑病、带状疱疹再激活、多形性红斑、Stevens-Johnson综合征和中毒性表皮坏死松解症(TEN)。最常见的新冠肺炎疫苗相关皮肤表现是延迟的局部反应,其中约66%与莫德纳疫苗有关,33%与辉瑞疫苗有关。除了轻度注射部位反应外,严重反应包括过敏反应和TEN。除Stevens-Johnson综合征和过敏反应外,大多数反应虽然不可预测且无法预防,但都是轻微的,可以根据症状进行治疗。这项审查的结果应该使初级保健医生和皮肤科医生能够更快地进行诊断并开始及时干预。
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来源期刊
Journal of Family and Community Medicine
Journal of Family and Community Medicine PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.00
自引率
3.70%
发文量
20
审稿时长
37 weeks
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