The Diagnostic Value of Neutrophil to Lymphocyte Ratio as an Effective Biomarker for Neuromyelitis Optica Spectrum Disorder.

Journal of physical medicine and rehabilitation (Wilmington, Del.) Pub Date : 2023-01-01 DOI:10.33696/rehabilitation.5.035

Navid Fazlinejad, Samaneh Hosseini, Shirin Yaghoobpoor, Mina Dehghani, Hanieh Bazrafshan, Shokoufeh Khanzadeh, Brandon Lucke-Wold

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Abstract

Background: Neuromyelitis Optica (NMO) is a serious condition associated with inflammation. Early diagnosis and detection are critical for early intervention. In this systematic review, we investigate the role of the neutrophil to lymphocyte ratio (NLR) as an important biomarker for NMO.

Methods: Ten studies were selected that were sufficiently high quality and then checked for quality. The studies were organized by English language and selective inclusion criteria.

Results: NLR was significantly increased in NMO patients compared to controls. The ratio was specifically proportional to severity of disease. More severe disease had a higher ratio.

Conclusion: NLR offers a reliable and affordable method for early detection of disease severity. This can help guide appropriate treatment selection and monitor treatment response.

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中性粒细胞与淋巴细胞比值作为神经脊髓炎谱系障碍的有效生物标志物的诊断价值》（The Diagnostic Value of Neutrophil to Lymphocyte Ratio as an Effective Biomarker for Neuromyelitis Optica Spectrum Disorder）。

背景：神经脊髓炎（NMO）是一种与炎症相关的严重疾病。早期诊断和检测对于早期干预至关重要。在这篇系统综述中，我们研究了中性粒细胞与淋巴细胞比值（NLR）作为 NMO 重要生物标志物的作用：方法：筛选出十项质量足够高的研究，然后进行质量检查。结果：NLR在NMO患者中明显升高：结果：与对照组相比，NMO 患者的 NLR 明显升高。该比率与疾病的严重程度成正比。结论：结论：NLR为早期检测疾病严重程度提供了一种可靠而经济的方法。结论：NLR为早期检测疾病严重程度提供了一种可靠而经济的方法，有助于指导适当的治疗选择和监测治疗反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of physical medicine and rehabilitation (Wilmington, Del.)

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