Pigmented Desmoplastic Trichilemmoma Arising in Nevus Sebaceous: A Potential Mimicker of Pigmented Basal Cell Carcinoma.

IF 1.4 Q3 DERMATOLOGY Skin Appendage Disorders Pub Date : 2023-08-01 Epub Date: 2023-04-13 DOI:10.1159/000530001

Meshal M Alhameedy, Omar A Alrobaish, Sulaiman Almarshoud, Rand Albahli

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Abstract

Introduction: Trichilemmomas are a form of benign adnexal neoplasm with differentiation toward the follicular outer sheath. Nevus sebaceous (NS) of Jadassohn is a congenital malformation characterized as a nonhereditary hamartoma of the adnexal structures of the skin, mainly the pilosebaceous unit. NS represents a fertile field for the development of secondary adnexal neoplasms, commonly benign but occasionally malignant. To our knowledge, one case of a pigmented desmoplastic trichilemmoma (DT) has been reported in the English literature.

Case presentation: We report a case of a 36-year-old male with pigmented DT that developed on long-standing congenital NS, mimicking pigmented basal cell carcinoma (BCC), which was successfully excised with 4-mm margins.

Conclusion: Pigmented DT may mimic pigmented BCC on clinical and dermatoscopic examination; therefore, histological evaluation is always recommended to confirm the diagnosis.

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皮脂腺痣中出现的色素脱鳞屑性三毛瘤：色素性基底细胞癌的潜在模仿者

导言三毛瘤是一种向毛囊外鞘分化的良性附件肿瘤。贾达松皮脂腺痣（NS）是一种先天性畸形，其特点是皮肤附件结构（主要是皮脂腺单位）的非遗传性瘤。NS 是继发性附件肿瘤发生的沃土，通常是良性的，但偶尔也有恶性的。据我们所知，英文文献中仅报道过一例色素脱鳞屑性三绒毛膜瘤（DT）：我们报告了一例 36 岁男性色素性脱色素性三尖瓣瘤病例，该病例发生在长期存在的先天性 NS 上，模仿色素性基底细胞癌（BCC），在 4 毫米的边缘成功切除：结论：色素性 DT 可能会在临床和皮肤镜检查中模仿色素性 BCC；因此，建议进行组织学评估以确诊。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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