Pharmaceutical/Biomedical Applications of Electrospun Nanofibers - Comprehensive Review, Attentive to Process Parameters and Patent Landscape.

Q2 Pharmacology, Toxicology and Pharmaceutics Pharmaceutical nanotechnology Pub Date : 2024-01-01 DOI:10.2174/2211738511666230911163249

Varshini Hemmanahalli Ramesh, Prakash Goudanavar, Bevenahalli Ramesh, Nimbagal Raghavendra Naveen, Buduru Gowthami

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Abstract

Nanotechnology is a new science and business endeavour with worldwide economic benefits. Growing knowledge of nanomaterial fabrication techniques has increased the focus on nanomaterial preparation for various purposes. Nanofibers are one-dimensional nanomaterials having distinct physicochemical properties and characteristics. Nanofibers are nanomaterial types with a cross-sectional dimension of tens to hundreds of nanometres. They may create high porosity mesh networks with significant interconnections among pores, making them suitable for advanced applications. Electrospinning stands out for its ease of use, flexibility, low cost, and variety among the approaches described in the literature. The most common method for making nanofibers is electrospinning. This article extensively describes and summarizes the impact of various process variables on the fabrication of nanofibers. Special attention has been given to scientific and patent prospection to confirm the research interests in nanofibers.

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电纺纳米纤维的制药/生物医学应用--全面回顾，关注工艺参数和专利情况。

纳米技术是一门新科学，也是一项具有全球经济效益的商业活动。人们对纳米材料制造技术的了解日益加深，因此更加关注用于各种用途的纳米材料制备。纳米纤维是一维纳米材料，具有独特的物理化学性质和特征。纳米纤维是一种横截面尺寸为几十到几百纳米的纳米材料。纳米纤维可形成高孔隙率的网状网络，孔隙之间有明显的相互连接，因此适合高级应用。在文献描述的各种方法中，电纺丝因其易用性、灵活性、低成本和多样性而脱颖而出。电纺丝是制造纳米纤维最常用的方法。本文广泛介绍并总结了各种工艺变量对纳米纤维制造的影响。文章特别关注科学和专利前景，以确认纳米纤维的研究兴趣。

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来源期刊

Pharmaceutical nanotechnology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

4.20

自引率

0.00%

发文量

期刊介绍： Pharmaceutical Nanotechnology publishes original manuscripts, full-length/mini reviews, thematic issues, rapid technical notes and commentaries that provide insights into the synthesis, characterisation and pharmaceutical (or diagnostic) application of materials at the nanoscale. The nanoscale is defined as a size range of below 1 µm. Scientific findings related to micro and macro systems with functionality residing within features defined at the nanoscale are also within the scope of the journal. Manuscripts detailing the synthesis, exhaustive characterisation, biological evaluation, clinical testing and/ or toxicological assessment of nanomaterials are of particular interest to the journal’s readership. Articles should be self contained, centred around a well founded hypothesis and should aim to showcase the pharmaceutical/ diagnostic implications of the nanotechnology approach. Manuscripts should aim, wherever possible, to demonstrate the in vivo impact of any nanotechnological intervention. As reducing a material to the nanoscale is capable of fundamentally altering the material’s properties, the journal’s readership is particularly interested in new characterisation techniques and the advanced properties that originate from this size reduction. Both bottom up and top down approaches to the realisation of nanomaterials lie within the scope of the journal.