Virtual stress plays tricks on cells.

IF 9 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Cell Systems Pub Date : 2023-07-19 DOI:10.1016/j.cels.2023.06.006

Alexander Loewer

引用次数: 0

Abstract

Optogenetics enables the induction of virtual stress, which separates stress signaling from cellular damage. This provides new insights into the dynamics of the integrated stress response and reveals the mechanisms through which cells form memories of past stress events to guide their response to acute stress.

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虚拟压力对细胞起作用。

光遗传学能够诱导虚拟压力，将压力信号与细胞损伤分离。这为综合应激反应的动力学提供了新的见解，并揭示了细胞通过形成过去应激事件的记忆来指导其对急性应激反应的机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Systems Medicine-Pathology and Forensic Medicine

CiteScore

16.50

自引率

1.10%

发文量

审稿时长

42 days

期刊介绍： In 2015, Cell Systems was founded as a platform within Cell Press to showcase innovative research in systems biology. Our primary goal is to investigate complex biological phenomena that cannot be simply explained by basic mathematical principles. While the physical sciences have long successfully tackled such challenges, we have discovered that our most impactful publications often employ quantitative, inference-based methodologies borrowed from the fields of physics, engineering, mathematics, and computer science. We are committed to providing a home for elegant research that addresses fundamental questions in systems biology.