Efficacy and safety of vena cava filters in preventing pulmonary embolism: A systematic review and meta-analysis.

IF 1.6 4区 医学 Q3 PERIPHERAL VASCULAR DISEASE Phlebology Pub Date : 2023-08-01 DOI:10.1177/02683555231185649
Huang-Tai Miao, Xiao-Ying Li, Can Zhou, Ying Liang, Shao-Ping Nie
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Abstract

Objectives: To assess the treatment effectiveness of inferior vena cava filters (IVCF) versus non-IVCF for patients undergoing varies conditions.

Methods: We systematically searched the databases to identify eligible RCTs from their inception up to 9/20/2020. The primary endpoint was pulmonary embolism (PE), while the secondary endpoints included deep-vein thrombosis (DVT), major bleeding, and all-cause mortality. The RRs with 95% CIs were applied as effect estimates for the treatment effectiveness of IVCF versus non-IVCF and calculated by using the random-effects model.

Results: 1,137 patients of 5 RCTs were enrolled. There were no significant differences between IVCF and non-IVCF for the risk of PE, major bleeding, and all-cause mortality, while the risk of DVT was significantly increased for patients treated with IVCF.

Conclusions: The use of IVCF did not yield any benefits on PE, major bleeding, and all-cause mortality risk for patients undergoing various conditions, while the risk of DVT was significantly increased for patients treated with IVCF.

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腔静脉过滤器预防肺栓塞的有效性和安全性:一项系统综述和荟萃分析。
目的:评估下腔静脉过滤器(IVCF)与非IVCF对不同情况患者的治疗效果。方法:我们系统地检索数据库,找出符合条件的rct,从它们开始到2020年9月20日。主要终点是肺栓塞(PE),次要终点包括深静脉血栓形成(DVT)、大出血和全因死亡率。采用95% ci的rr作为IVCF与非IVCF治疗效果的效应估计,并使用随机效应模型计算。结果:纳入5项随机对照试验的1137例患者。IVCF与非IVCF在PE、大出血和全因死亡率方面无显著差异,而IVCF患者发生DVT的风险明显增加。结论:对于各种情况的患者,使用IVCF对PE、大出血和全因死亡风险没有任何益处,而使用IVCF治疗的患者发生DVT的风险显著增加。
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来源期刊
Phlebology
Phlebology 医学-外周血管病
CiteScore
3.30
自引率
11.80%
发文量
84
审稿时长
6-12 weeks
期刊介绍: The leading scientific journal devoted entirely to venous disease, Phlebology is the official journal of several international societies devoted to the subject. It publishes the results of high quality studies and reviews on any factor that may influence the outcome of patients with venous disease. This journal provides authoritative information about all aspects of diseases of the veins including up to the minute reviews, original articles, and short reports on the latest treatment procedures and patient outcomes to help medical practitioners, allied health professionals and scientists stay up-to-date on developments. Print ISSN: 0268-3555
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