Detection of Brain Tumor Employing Residual Network-based Optimized Deep Learning

IF 1.5 4区 医学 Q4 CHEMISTRY, MEDICINAL Current computer-aided drug design Pub Date : 2024-08-06 DOI:10.2174/1573409920666230816090626
Saransh Rohilla, Shruti Jain
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Abstract

Background: Diagnosis and treatment planning play a very vital role in improving the survival of oncological patients. However, there is high variability in the shape, size, and structure of the tumor, making automatic segmentation difficult. The automatic and accurate detection and segmentation methods for Brain tumors are proposed in this paper.

Methods: A modified ResNet50 model was used for tumor detection, and a ResUNetmodel-based convolutional neural network for segmentation is proposed in this paper. The detection and segmentation were performed on the same dataset consisting of pre-contrast, FLAIR, and postcontrast MRI images of 110 patients collected from the Cancer Imaging Archive. Due to the use of Residual Networks, the authors observed improvement in evaluation parameters, such as accuracy for tumor detection and dice similarity coefficient for tumor segmentation.

Results: The accuracy of tumor detection and Dice Similarity Coefficient achieved by the segmentation model were 96.77% and 0.893, respectively, for the TCIA dataset. The results were compared based on manual segmentation and existing segmentation techniques. The tumor mask was also individually compared to the ground truth using the SSIM value. The proposed detection and segmentation models were validated on BraTS2015 and BraTS2017 datasets, and the results were consensus.

Conclusion: The use of residual networks in both the detection and the segmentation model resulted in improved accuracy and DSC score. DSC score was increased by 5.9% compared to the UNet model, and the accuracy of the model was increased from 92% to 96.77% for the test set.

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利用基于残差网络的优化深度学习检测脑肿瘤
背景:诊断和治疗计划对提高肿瘤患者的生存率起着至关重要的作用。然而,肿瘤的形状、大小和结构变化很大,给自动分割带来了困难。本文提出了自动、准确的脑肿瘤检测和分割方法:方法:本文使用改进的 ResNet50 模型进行肿瘤检测,并提出了基于 ResUNetmodel 的卷积神经网络进行分割。检测和分割是在同一数据集上进行的,该数据集由癌症影像档案馆收集的 110 名患者的对比前、FLAIR 和对比后 MRI 图像组成。由于使用了残差网络,作者观察到了评估参数的改进,如肿瘤检测的准确性和肿瘤分割的骰子相似系数:结果:在 TCIA 数据集上,分割模型的肿瘤检测准确率和骰子相似系数分别为 96.77% 和 0.893。在人工分割和现有分割技术的基础上对结果进行了比较。此外,还使用 SSIM 值将肿瘤掩膜与地面实况进行了单独比较。在 BraTS2015 和 BraTS2017 数据集上对所提出的检测和分割模型进行了验证,结果达成了共识:结论:在检测和分割模型中使用残差网络提高了准确性和 DSC 分数。与 UNet 模型相比,DSC 分数提高了 5.9%,模型在测试集上的准确率从 92% 提高到 96.77%。
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来源期刊
Current computer-aided drug design
Current computer-aided drug design 医学-计算机:跨学科应用
CiteScore
3.70
自引率
5.90%
发文量
46
审稿时长
>12 weeks
期刊介绍: Aims & Scope Current Computer-Aided Drug Design aims to publish all the latest developments in drug design based on computational techniques. The field of computer-aided drug design has had extensive impact in the area of drug design. Current Computer-Aided Drug Design is an essential journal for all medicinal chemists who wish to be kept informed and up-to-date with all the latest and important developments in computer-aided methodologies and their applications in drug discovery. Each issue contains a series of timely, in-depth reviews, original research articles and letter articles written by leaders in the field, covering a range of computational techniques for drug design, screening, ADME studies, theoretical chemistry; computational chemistry; computer and molecular graphics; molecular modeling; protein engineering; drug design; expert systems; general structure-property relationships; molecular dynamics; chemical database development and usage etc., providing excellent rationales for drug development.
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