Psoriasis: is it a risk factor for cardiovascular diseases?

IF 2.9 4区医学 Q2 DERMATOLOGY Journal of Dermatological Treatment Pub Date : 2022-12-01 DOI:10.1080/09546634.2022.2112137

Hesham Nada, Attef Elakhrass, Neven Ahmad, Mohamed Refaat

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引用次数: 0

Abstract

Background/objectives: Psoriasis, newly considered as a systemic inflammatory condition, has a high prevalence of cardiovascular diseases (CVDs), including atherosclerosis and myocardial infarction. Measurement of carotid artery intima-media thickness (C-IMT) represents a noninvasive diagnostic tool for predicting cardiovascular disorders. We aimed to determine if psoriatic patients have an increased risk for the development of cardiovascular disorders by assessment of the presence of subclinical atherosclerosis in psoriasis patients.

Methods: Forty adult psoriatic patients and 40 matched healthy controls were selected in this study. All participants were subjected to full history, examination, assessment of the severity of psoriasis using psoriasis area and severity index (PASI) score, measuring serum lipid profile (cholesterol, low density lipoprotein (LDL) and triglycerides) and C-IMT.

Results: Psoriatic patients showed significantly higher serum lipid profile findings and C-IMT. There was a positive statistically significant correlation between C-IMT and each of age of the patients (r = 0.760, p<.001) and severity of psoriasis (PASI score).

Conclusions: There is increased susceptibility to CVDs in psoriatic patients represented by increased incidence of subclinical atherosclerosis and dyslipidemia in our patients.

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牛皮癣:是心血管疾病的危险因素吗?

背景/目的:银屑病最近被认为是一种全身性炎症疾病，其心血管疾病(cvd)的患病率很高，包括动脉粥样硬化和心肌梗死。测量颈动脉内膜-中膜厚度(C-IMT)是一种预测心血管疾病的无创诊断工具。我们的目的是通过评估银屑病患者亚临床动脉粥样硬化的存在来确定银屑病患者发生心血管疾病的风险是否增加。方法:选取40例成年银屑病患者和40例健康对照。所有参与者都接受了完整的病史，检查，使用牛皮癣面积和严重程度指数(PASI)评分评估牛皮癣的严重程度，测量血脂(胆固醇，低密度脂蛋白(LDL)和甘油三酯)和C-IMT。结果:银屑病患者血清脂质谱和C-IMT均明显增高。C-IMT与患者各年龄段的相关性有统计学意义(r = 0.760)。结论:银屑病患者对心血管疾病的易感性增加，表现为亚临床动脉粥样硬化和血脂异常的发生率增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Dermatological Treatment 医学-皮肤病学

CiteScore

6.50

自引率

0.00%

发文量

145

审稿时长

6-12 weeks

期刊介绍： The Journal of Dermatological Treatment covers all aspects of the treatment of skin disease, including the use of topical and systematically administered drugs and other forms of therapy. The Journal of Dermatological Treatment is positioned to give dermatologists cutting edge information on new treatments in all areas of dermatology. It also publishes valuable clinical reviews and theoretical papers on dermatological treatments.