Risk of Obstructive Sleep Apnea in Saudi Male Boys with Duchenne Muscular Dystrophy (DMD).

Degenerative Neurological and Neuromuscular Disease Pub Date : 2023-08-15 eCollection Date: 2023-01-01 DOI:10.2147/DNND.S421399

Ahmed Bamaga, Lama Alqarni

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Abstract

Background: Duchenne muscular dystrophy (DMD) patients are at a high risk of developing sleep-related breathing disorders (SRBD) such as obstructive sleep apnea (OSA). This study aimed to determine the risk of developing OSA among DMD patients.

Methods: This cross-sectional study was conducted from February 2022 to July 2022 in a tertiary healthcare facility. As a screening tool for OSA, we used the Pediatric Sleep Questionnaire (PSQ).

Results: Subjects included 60 boys with DMD, mean age 10.15 ± 3.54 years. The mean BMI for all subjects was 18.9 ± 4.08 kg/m2. Of these, 22 (36.7%) children were at high risk of OSA. Children who were overweight, and on steroids tended to be at higher risk of developing OSA (P < 0.043) and (P < 0.029) respectively.

Conclusion: Our study shows a significant risk of OSA in DMD patients. Therefore, Sleep studies should be part of the standard of care for DMD patients.

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沙特男性杜氏肌肉萎缩症 (DMD) 男孩患阻塞性睡眠呼吸暂停的风险。

背景：杜氏肌营养不良症（DMD）患者患阻塞性睡眠呼吸暂停（OSA）等睡眠相关呼吸障碍（SRBD）的风险很高。本研究旨在确定 DMD 患者罹患 OSA 的风险：这项横断面研究于 2022 年 2 月至 2022 年 7 月在一家三级医疗机构进行。作为 OSA 的筛查工具，我们使用了儿科睡眠问卷（PSQ）：受试者包括 60 名患有 DMD 的男孩，平均年龄（10.15 ± 3.54）岁。所有受试者的平均体重指数（BMI）为 18.9 ± 4.08 kg/m2。其中，22 名儿童（36.7%）是 OSA 的高危人群。超重和服用类固醇的儿童患 OSA 的风险往往更高（P < 0.043）和（P < 0.029）：我们的研究表明，DMD 患者罹患 OSA 的风险很高。因此，睡眠研究应成为 DMD 患者标准护理的一部分。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Degenerative Neurological and Neuromuscular Disease

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