The interaction of e-cigarette use and mental health symptoms on risk of cigarette smoking initiation among young adults in the United States

IF 5.2 1区医学 Q1 PSYCHIATRY Addiction Pub Date : 2023-08-24 DOI:10.1111/add.16319

Alyssa F. Harlow, Dae-Hee Han, Sandrah P. Eckel, Rob McConnell, Adam M. Leventhal, Jessica L. Barrington-Trimis

{"title":"The interaction of e-cigarette use and mental health symptoms on risk of cigarette smoking initiation among young adults in the United States","authors":"Alyssa F. Harlow, Dae-Hee Han, Sandrah P. Eckel, Rob McConnell, Adam M. Leventhal, Jessica L. Barrington-Trimis","doi":"10.1111/add.16319","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background and Aims</h3>\n \n <p>It is unknown whether young adults who vape nicotine and have poor mental health have greater risk of smoking initiation than expected based on individual risks of vaping and mental health alone. This study aimed to estimate the joint association of vaping and mental health symptoms with smoking initiation among young adults, and test for additive interaction between vaping and mental health in smoking initiation risk.</p>\n </section>\n \n <section>\n \n <h3> Design</h3>\n \n <p>Using five waves of the Population Assessment of Tobacco and Health (wave 1, 2013–2014; wave 2, 2014–2015; wave 3, 2015–2016; wave 4, 2016–2018; wave 5, 2018–2019), we estimated risk differences (RD) for the association of time-varying and time-lagged vaping and internalizing (e.g., anxiety, depressive) and externalizing (e.g., inattention/hyperactivity) mental health symptoms with cigarette smoking initiation at follow-up, over four 1-year intervals. We calculated interaction contrasts (IC) to estimate the excess risk of smoking initiation attributable to the interaction of vaping and mental health symptoms.</p>\n </section>\n \n <section>\n \n <h3> Setting</h3>\n \n <p>United States.</p>\n </section>\n \n <section>\n \n <h3> Participants</h3>\n \n <p>A total of 6908 cigarette-naïve individuals aged 18–24 years.</p>\n </section>\n \n <section>\n \n <h3> Measurements</h3>\n \n <p>Exposures included current (past-30 day) vaping and internalizing and externalizing mental health symptoms (high vs moderate/low symptoms). The outcome was smoking initiation (ever cigarette use) after 1 year.</p>\n </section>\n \n <section>\n \n <h3> Findings</h3>\n \n <p>The per-interval risk of smoking initiation was 7.6% (1039 cases/13 712 person-intervals). Compared with noncurrent vaping and moderate/low mental health symptoms, adjusted RDs for current vaping and high mental health symptoms were 17.2% (95% confidence interval [CI]: 7.2% to 27.3%) for internalizing and 18.7% (95%CI: 8.1% to 29.2%) for externalizing symptoms. The excess risk attributed to interaction of current vaping and high externalizing symptoms was IC = 11.3% (95%CI: 1.3% to 21.2%; <i>P</i> = 0.018), with inconclusive findings for internalizing symptoms (IC = 7.7% [95%CI: −2.2% to 17.7%; <i>P</i> = 0.097]).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>There is possible, but inconclusive, superadditivity between vaping and mental health in risk of smoking initiation among young adults in the United States.</p>\n </section>\n </div>","PeriodicalId":109,"journal":{"name":"Addiction","volume":"118 12","pages":"2317-2326"},"PeriodicalIF":5.2000,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Addiction","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/add.16319","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Background and Aims

It is unknown whether young adults who vape nicotine and have poor mental health have greater risk of smoking initiation than expected based on individual risks of vaping and mental health alone. This study aimed to estimate the joint association of vaping and mental health symptoms with smoking initiation among young adults, and test for additive interaction between vaping and mental health in smoking initiation risk.

Design

Using five waves of the Population Assessment of Tobacco and Health (wave 1, 2013–2014; wave 2, 2014–2015; wave 3, 2015–2016; wave 4, 2016–2018; wave 5, 2018–2019), we estimated risk differences (RD) for the association of time-varying and time-lagged vaping and internalizing (e.g., anxiety, depressive) and externalizing (e.g., inattention/hyperactivity) mental health symptoms with cigarette smoking initiation at follow-up, over four 1-year intervals. We calculated interaction contrasts (IC) to estimate the excess risk of smoking initiation attributable to the interaction of vaping and mental health symptoms.

Setting

United States.

Participants

A total of 6908 cigarette-naïve individuals aged 18–24 years.

Measurements

Exposures included current (past-30 day) vaping and internalizing and externalizing mental health symptoms (high vs moderate/low symptoms). The outcome was smoking initiation (ever cigarette use) after 1 year.

Findings

The per-interval risk of smoking initiation was 7.6% (1039 cases/13 712 person-intervals). Compared with noncurrent vaping and moderate/low mental health symptoms, adjusted RDs for current vaping and high mental health symptoms were 17.2% (95% confidence interval [CI]: 7.2% to 27.3%) for internalizing and 18.7% (95%CI: 8.1% to 29.2%) for externalizing symptoms. The excess risk attributed to interaction of current vaping and high externalizing symptoms was IC = 11.3% (95%CI: 1.3% to 21.2%; P = 0.018), with inconclusive findings for internalizing symptoms (IC = 7.7% [95%CI: −2.2% to 17.7%; P = 0.097]).

Conclusions

There is possible, but inconclusive, superadditivity between vaping and mental health in risk of smoking initiation among young adults in the United States.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

电子烟使用和心理健康症状对美国年轻人吸烟风险的影响。

背景和目的：目前尚不清楚吸食尼古丁且心理健康状况不佳的年轻人是否比预期的吸烟风险更大，仅基于吸食电子烟和心理健康的个人风险。这项研究旨在评估年轻人中电子烟和心理健康症状与吸烟的共同关系，并测试电子烟与心理健康在吸烟风险中的加性相互作用。设计：使用五波烟草与健康人口评估（第1波，2013-2014；第2波，2014-2015；第3波，2015-2016；第4波，2016-2018；第5波，2018-2019），我们估计了时变和时间滞后的电子烟和内化（如焦虑、抑郁）和外化（如注意力不集中/多动）心理健康症状与随访时开始吸烟的相关性的风险差异（RD），时间间隔为4个1年。我们计算了相互作用对比度（IC），以估计由于电子烟和心理健康症状的相互作用而导致的吸烟过度风险。背景：美国。参与者：共有6908名18-24岁的香烟天真者年。测量：暴露包括电流（过去30 一天）吸电子烟以及内化和外化心理健康症状（高症状与中等/低症状）。结果是1年后开始吸烟（曾经吸烟）。结果：每间隔吸烟的风险为7.6%（1039例/13例） 712人间隔）。与非当前吸烟和中度/低度心理健康症状相比，当前吸烟和高度心理健康症状的内部化校正RD为17.2%（95%置信区间[CI]:7.2%-27.3%），外部化症状的校正RD为18.7%（95%CI:8.1%-29.2%）。归因于当前电子烟和高外化症状相互作用的过度风险为IC = 11.3%（95%CI:1.3%-21.2%；P = 0.018），对于内化症状（IC = 7.7%[95%CI:-2.2%至17.7%；P = 0.097]）。结论：在美国年轻人开始吸烟的风险中，电子烟和心理健康之间可能存在但不确定的超加性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Addiction 医学-精神病学

CiteScore

10.80

自引率

6.70%

发文量

319

审稿时长

3 months

期刊介绍： Addiction publishes peer-reviewed research reports on pharmacological and behavioural addictions, bringing together research conducted within many different disciplines. Its goal is to serve international and interdisciplinary scientific and clinical communication, to strengthen links between science and policy, and to stimulate and enhance the quality of debate. We seek submissions that are not only technically competent but are also original and contain information or ideas of fresh interest to our international readership. We seek to serve low- and middle-income (LAMI) countries as well as more economically developed countries. Addiction’s scope spans human experimental, epidemiological, social science, historical, clinical and policy research relating to addiction, primarily but not exclusively in the areas of psychoactive substance use and/or gambling. In addition to original research, the journal features editorials, commentaries, reviews, letters, and book reviews.