Updates on Intraoperative Neurophysiology During Surgery for Spinal Dysraphism.

Claudia Pasquali, Federica Basaldella, Francesco Sala
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Abstract

Spinal dysraphism is a group of disorders resulting from an embryologic failure of spinal cord development which can lead to a radicular-medullary mechanical stretch that generates vascular compromise and hypoxic-ischemic damage to the nervous structures of the conus-cauda region.Thus, the clinical relevance of the different types of spinal dysraphism is related to the possible neurologic deficits resulting from spinal cord tethering. The clinical presentation is heterogenous: from asymptomatic to very compromised patients. The indications and the time of a detethering surgery are still subject of debate, although there is an agreement on the high standards of treatment that have to be offered by the surgery. Intraoperative neurophysiology (ION) contributes to the safety of tethered cord surgery in reducing the risks of iatrogenic neurological damages.

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脊柱异常症术中神经生理学的最新进展。
脊髓发育异常是一组由脊髓发育的胚胎学失败引起的疾病,可导致神经根-髓质机械拉伸,导致血管损伤和尾锥体神经结构的缺氧缺血性损伤。因此,不同类型脊柱发育异常的临床相关性与脊髓栓系可能导致的神经功能缺陷有关。临床表现是异质的:从无症状到非常虚弱的患者。尽管在手术必须提供的高标准治疗方面达成了一致,但解栓手术的适应症和时间仍然是争论的主题。术中神经生理学(ION)有助于降低医源性神经损伤风险的脊髓栓系手术的安全性。
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