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Preoperative Assessments for Selective Dorsal Rhizotomy. 选择性背根切断术的术前评估。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-86441-4_7
Olivia Shien Hui Lee

Selective dorsal rhizotomy (SDR) in cerebral palsy care aims to improve gait and function in ambulatory children and enhance comfort in nonambulatory children. This assessment and planning process for SDR requires a multidisciplinary team to work closely with patients and families to weigh the benefits and risks of SDR. Preoperative assessments allow the clinical team to select suitable candidates, set realistic goals, and optimise outcomes. These evaluations include physical measures, assessment of gross motor function and functional daily living skills, and gait analysis to better quantify the impact of spasticity in the SDR candidate. Further orthopaedic evaluations are required to identify pain and musculoskeletal issues, guiding subsequent post-SDR interventions. Additionally, assessments of quality-of-life assessments ensure a comprehensive rehabilitation plan that includes psychosocial support. This chapter discusses the comprehensive preoperative rehabilitation assessments that assist clinicians and families in making shared decisions about SDR.

选择性脊背神经根切断术(SDR)在脑瘫护理中的应用旨在改善行走儿童的步态和功能,提高非行走儿童的舒适度。特别提款权的评估和规划过程需要一个多学科团队与患者和家属密切合作,权衡特别提款权的收益和风险。术前评估允许临床团队选择合适的候选人,设定现实的目标,并优化结果。这些评估包括物理测量,大运动功能和功能性日常生活技能的评估,以及步态分析,以更好地量化痉挛对SDR候选人的影响。需要进一步的骨科评估来识别疼痛和肌肉骨骼问题,指导后续sdr后干预。此外,生活质量评估确保了包括社会心理支持在内的全面康复计划。本章讨论了全面的术前康复评估,以帮助临床医生和家庭共同做出关于SDR的决定。
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引用次数: 0
Blake Pouch: It Is Time to Revisit Classical Descriptions on the Development of the Roof of the Fourth Ventricle. 是时候重新审视关于第四脑室顶部发展的经典描述了。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-90762-3_1
Martin Catala

Cystic anomalies of the posterior fossa constitute an important chapter of the malformations of this region. Their interpretation is largely based on the existence of a pouch described by Joseph Blake in 1900. We have reviewed the ancient literature on which this description is based. All human data were obtained from only three fetuses. The histological and embryological analysis of these observations leads us to remain very cautious as to their significance. Indeed, this region of the posterior fossa is very fragile and subject to numerous technical artifacts. In addition, errors in fetal age lead us to believe that one of the observations cannot be used. It is therefore appropriate to be very careful when using this old literature. All these elements justify the need to revisit this problem in order to determine the normal development of this region in humans.

后窝的囊性异常是该区域畸形的重要一章。他们的解释很大程度上是基于约瑟夫·布莱克在1900年描述的一个袋子的存在。我们已经回顾了这一描述所依据的古代文献。所有人类数据仅来自三个胎儿。对这些观察的组织学和胚胎学分析使我们对它们的意义保持非常谨慎的态度。事实上,后窝的这个区域非常脆弱,容易受到许多人工制品的影响。此外,胎儿年龄的错误使我们相信其中一个观察结果不能使用。因此,在使用这些古老的文献时,应该非常小心。所有这些因素都证明有必要重新审视这个问题,以确定人类这一区域的正常发育。
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引用次数: 0
Endoscopic Strip Craniectomy for the Treatment of Single Suture Craniosynostosis. 内窥镜条形颅骨切除术治疗单缝线颅缝闭锁。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-90762-3_12
Katherine Holste, John Lynes, Suresh N Magge

The treatment of craniosynostosis has evolved significantly over the past few decades. While open calvarial vault reconstruction remains a good treatment option, minimally invasive techniques have been shown to yield excellent results in children treated at a young age. This chapter details the use of endoscopic strip craniectomy with postoperative helmet therapy. This surgical option relies on early release of the fused suture to allow the child's own brain growth, plus use of a cranial molding helmet, to allow for correction of head shape. This chapter details the technique used to correct sagittal, metopic, and unicoronal craniosynostosis. Compared to open surgery, studies have shown that endoscopic surgery has comparable aesthetic outcomes and improved perioperative outcomes, such as blood loss, rate of blood transfusion, and time of surgery. This chapter reviews the techniques, aesthetic outcomes, cognitive outcomes, and advances in our knowledge of the genetics of craniosynostosis.

在过去的几十年里,颅缝闭锁的治疗有了显著的发展。虽然开放性颅穹窿重建仍然是一个很好的治疗选择,但微创技术已被证明在儿童早期治疗中取得了良好的效果。本章详细介绍了内镜下条带颅骨切除术与术后头盔治疗的应用。这种手术方案依赖于早期解除融合缝合线,以允许儿童自己的大脑发育,再加上使用颅骨成型头盔,以允许纠正头部形状。本章详细介绍了用于纠正矢状、异位和单冠状颅缝闭塞的技术。研究表明,与开放手术相比,内镜手术具有相当的美观效果,并改善了围手术期结果,如失血量、输血率和手术时间。本章回顾了颅缝闭锁的技术、美学结果、认知结果和遗传学知识的进展。
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引用次数: 0
Patient Selection in Selective Dorsal Rhizotomy (SDR). 选择性背根切断术(SDR)的患者选择。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-86441-4_16
Benjamin J Hall, Conor S Gillespie, Christine Sneade, Deborah Quirk, Dawn Hennigan, Benedetta Pettorini

For almost as long as selective dorsal rhizotomy (SDR) has existed, there has been debate surrounding which patients should be eligible to undergo the procedure. The selection criteria used to identify suitable surgical candidates have remained largely unchanged for the last three decades, despite the popularity and use of the procedure increasing. Historically, those aged between 3 and 9 years, those of GMFCS level 2 or 3, and those without evidence of dystonia were considered for SDR. In recent years, as the procedure has continued to develop, however, these parameters are expanding, with evidence to suggest a much broader cohort of patients may benefit from SDR than once thought. This chapter seeks to review current practice in patient selection for SDR, as well as the potential directions that this controversial discussion may move towards in the future.

几乎只要选择性背根切断术(SDR)存在,就有关于哪些患者应该有资格接受手术的争论。在过去的三十年中,尽管手术的普及和使用越来越多,但用于确定合适的手术候选人的选择标准基本保持不变。历史上,年龄在3 - 9岁之间、GMFCS等级为2级或3级以及无肌张力障碍证据的患者被认为是SDR患者。然而,近年来,随着该手术的不断发展,这些参数正在扩大,有证据表明,从SDR中受益的患者群体可能比以前想象的要广泛得多。本章旨在回顾SDR患者选择的当前实践,以及这一有争议的讨论可能在未来走向的潜在方向。
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引用次数: 0
Rhizotomy Surgery at the Conus Medullaris. 髓圆锥根切断术。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-86441-4_8
Kevin Paul Ferraris, Ash Singhal

Selective dorsal rhizotomy (SDR) has been an important surgical treatment for spasticity for decades. Broadly, there are two surgical technique options-via a multilevel laminotomy/laminectomy or via a single-level laminectomy and conus approach. This latter approach is described in detail in this chapter, with discussion of patient selection and a focus on surgical techniques including the integration of electromyography (EMG).

选择性背根切断术(SDR)几十年来一直是治疗痉挛的重要手术方法。总的来说,有两种手术技术选择-通过多节段椎板切开术/椎板切除术或通过单节段椎板切除术和圆锥入路。后一种方法在本章中详细描述,讨论患者选择和重点手术技术,包括肌电图(EMG)的整合。
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引用次数: 0
Dorsal Rhizotomy at the Intradural Juxtaforaminal Zone. 硬膜内椎间孔旁区背侧根切断术。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-86441-4_11
George Georgoulis, Anthony Joud, Marc Sindou

To optimize the efficacy of dorsal rhizotomy (DRh) in treating spasticity associated with cerebral palsy, the authors advocate for individual access (intradurally) to all roots from L2 to S2. The initial step involves the use of electrical stimulation of the ventral root (VR) to confirm their anatomical identity and determine their corresponding myotomal territory of innervation, which is known to exhibit interindividual variability (anatomical mapping). The primary objective is then to employ dorsal root (DR) stimulation to assess their respective reflexive excitability levels (physiological testing). To mitigate the risk of spine destabilization, access is gained through enlarged interlaminar openings while preserving the spinous processes and interspinous ligaments. This approach is termed Keyhole Interlaminar Dorsal rhizotomy (KIDr). Intradural access to the roots is achieved at their preforaminal zone, through a L1-L2 opening for the L2 and L3 roots, L3-L4 opening for the L4 and L5 roots, and L5-S1 opening for the L5 and S1 roots. Under microsurgical visualization, at each exposed root level, the VR is stimulated to verify its myotomal distribution, and the DR is stimulated to estimate the segmental reflexive excitability using Fasano's grading system, allowing for the adjustment of the number of rootlets per root to be severed. In our practice, indications are primarily based on the Gross Motor Function Classification System (GMFCS): for individuals classified as levels III and IV, the goal is to enhance functional status and prevent or halt deformities; for those at level V and quadriplegic patients, the aim is to improve comfort, reduce pain, facilitate care, and alleviate upper limb disability through the "distant effects" often observed following lumbo-sacral rhizotomy. The timing of surgery is determined not only by age-related locomotor development but also by the plateau or deterioration of the Gross Motor Function Measure (GMFM) curve despite intensive rehabilitation efforts. As with all specialized centers, the surgical schedule is established in collaboration with a multidisciplinary team and documented in a comprehensive chart, alongside the Gain Attainment project.

为了优化背侧神经根切断术(DRh)治疗脑瘫相关痉挛的疗效,作者主张对L2至S2的所有神经根进行单独(局部)通路。第一步包括使用腹侧根(VR)的电刺激来确认它们的解剖学特征,并确定它们相应的肌瘤神经支配区域,这是已知的个体间变异性(解剖作图)。然后,主要目标是使用背根(DR)刺激来评估他们各自的反射兴奋性水平(生理测试)。为了减轻脊柱失稳的风险,在保留棘突和棘间韧带的情况下,通过扩大椎板间开口进入。这种方法被称为Keyhole椎间背根切开术(KIDr)。硬膜内通过L2和L3根的L1-L2开口,L4和L5根的L3-L4开口,L5和S1根的L5-S1开口,在椎间孔前区进入根。在显微外科可视化下,在每个暴露的根水平,刺激VR以验证其肌层分布,刺激DR以使用Fasano分级系统估计节段性反射兴奋性,允许调整每个根要切断的根的数量。在我们的实践中,适应症主要基于大运动功能分类系统(GMFCS):对于被分类为III级和IV级的个体,目标是增强功能状态并预防或停止畸形;对于那些V级和四肢瘫痪的患者,目的是通过腰骶神经根切断术后经常观察到的“远端效应”来改善舒适度、减轻疼痛、促进护理和减轻上肢残疾。手术的时机不仅取决于与年龄相关的运动发育,还取决于尽管进行了大量的康复治疗,但大运动功能测量(GMFM)曲线的平稳或恶化。与所有专业中心一样,手术时间表是与多学科团队合作制定的,并记录在综合图表中,与增益项目一起。
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引用次数: 0
Electromagnetic Navigation in Cranial Neurosurgery. 颅神经外科的电磁导航。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-90762-3_10
Elvis J Hermann, Joachim K Krauss

Electromagnetic cranial navigation is a valuable alternative to the more commonly used optoelectric navigation, and it has several advantages in different neurosurgical indications enhancing the accuracy of surgery. Obviating the use of sharp head fixation, it has become a very helpful tool in shunt surgery and in pediatric neurosurgery. In addition, its usefulness has been shown in neuroendoscopy, tumor surgery, aneurysm surgery, and skull base approaches. Here, we provide an overview on the technique of electromagnetic navigation and summarize its main indications and advantages in cranial neuronavigation.

电磁颅导航是一种有价值的替代更常用的光电导航,它在不同的神经外科指征中具有许多优点,提高了手术的准确性。避免使用尖锐的头固定,它已成为一个非常有用的工具,在分流手术和儿童神经外科。此外,它在神经内窥镜、肿瘤手术、动脉瘤手术和颅底入路中也有应用。本文对电磁导航技术进行了综述,并对电磁导航在颅神经导航中的主要适应症和优势进行了总结。
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引用次数: 0
Postoperative Functional Recovery and Rehabilitation Following Selective Dorsal Rhizotomy. 选择性背根切断术术后功能恢复与康复。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-86441-4_14
Neil Wimalasundera

Selective dorsal rhizotomy (SDR) has been practiced for many years; however, standardization of processes such as the surgical technique and rehabilitation protocols are only relatively recent phenomenon. Comparing data from various studies can be limited due to temporal changes in practice, different selection criteria for SDR, the heterogeneity of cerebral palsy and variable rehabilitation protocols. This chapter reviews the available evidence in relation to best practice for rehabilitation following SDR and explores factors affecting the short- and long-term outcome following SDR. This includes more easily measurable factors, such as the child's preoperative Gross Motor Function Measurement (GMFM) and severity of spasticity, to social and cognitive factors which can affect participation in rehabilitation.

选择性背根切开术(SDR)已实践多年;然而,标准化的过程,如手术技术和康复方案只是最近的现象。由于实践中的时间变化、SDR的选择标准不同、脑瘫的异质性和不同的康复方案,比较不同研究的数据可能受到限制。本章回顾了与SDR后康复最佳实践相关的现有证据,并探讨了影响SDR后短期和长期结果的因素。这包括更容易测量的因素,如儿童术前大运动功能测量(GMFM)和痉挛的严重程度,以及可能影响参与康复的社会和认知因素。
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引用次数: 0
Selection of Children with Spasticity Other Than Cerebral Palsy: Indications, Long-Term Outcome, and Exclusion Criteria. 脑瘫以外痉挛患儿的选择:适应症、长期预后和排除标准。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-86441-4_6
Pramath Kakodkar, Nooshin Shekari, Madhura Thipse, Debajyoti Datta, Albert Tu

Background: Selective dorsal rhizotomy (SDR) has been instrumental in improving functionality and mitigating lower extremity spasticity originating from a myriad of central nervous system (CNS) etiologies. Existing literature on SDR extensively discusses its utility in cerebral palsy (CP)-associated spasticity management. There is a void on the utility and guidance in patient selection for SDR in pediatric patients with non-CP-related spasticity.

Methods: A systematic review was performed on studies describing SDR outcomes in pediatric patients identified from Medline and Embase databases. Publications between January 1970 and August 2023 were included. Combinations of search terms "selective dorsal rhizotomy," "selective posterior rhizotomy," and "spasticity" were utilized. Pediatric patient studies with clinical data on spasticity, ambulation, procedural variables, and follow-up outcomes were included. Articles including patients without cerebral palsy as a primary diagnosis were reviewed in detail for outcomes after intervention.

Results: A total of 114 publications were identified, and of these, 11 fit inclusion criteria for a total of 127 patients. Most common non-CP etiologies for spasticity included hereditary spastic paraparesis (27.8%, n = 34), congenital syndrome (n = 7), and spinal cord injury (21.9%, n = 6). Compared to their baseline, SDR in non-CP-related etiologies demonstrated tone normalization (93%, n = 43 out of 45 patients) in most and improvement in ambulation (49.2%, n = 58 out of 118 patients) in a significant proportion of patients.

Conclusion: This systematic review on SDR in pediatric patients revealed effective spasticity control and improvement in ambulatory functionality in selected patients without cerebral palsy. Appropriate patient selection is keystone in achieving sustained benefits in functionality and quality of life.

背景:选择性背侧神经根切断术(SDR)在改善功能和减轻由中枢神经系统(CNS)病因引起的下肢痉挛方面发挥了重要作用。关于SDR的现有文献广泛讨论了其在脑瘫(CP)相关痉挛治疗中的应用。对于非cp相关性痉挛患儿的SDR患者选择的实用性和指导存在空白。方法:对Medline和Embase数据库中描述小儿SDR结局的研究进行系统回顾。其中包括1970年1月至2023年8月之间的出版物。结合搜索词“选择性背根切断术”,“选择性后根切断术”和“痉挛”被使用。包含痉挛、行走、程序变量和随访结果临床数据的儿科患者研究。文章包括没有脑瘫作为初步诊断的患者在干预后的结果进行了详细的回顾。结果:共纳入114篇文献,其中11篇符合纳入标准,共纳入127例患者。痉挛最常见的非cp病因包括遗传性痉挛性截瘫(27.8%,n = 34)、先天性综合征(n = 7)和脊髓损伤(21.9%,n = 6)。与基线相比,非cp相关病因的SDR在大多数患者中显示音调正常化(93%,45例患者中n = 43例),在很大一部分患者中显示行走能力改善(49.2%,118例患者中n = 58例)。结论:本系统综述显示,在非脑瘫患者中,SDR可有效控制痉挛并改善运动功能。适当的患者选择是实现功能和生活质量持续获益的关键。
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引用次数: 0
Surgical Treatment of Optic Pathway Hypothalamic Gliomas. 视神经通路下丘脑胶质瘤的外科治疗。
Pub Date : 2025-01-01 DOI: 10.1007/978-3-031-90762-3_2
Helmut Bertalanffy, Massimo Gallieni, Ramin Mahmoodi, Rudolf Fahlbusch, Souvik Kar, Concezio Di Rocco

This paper provides an overview of optic pathway hypothalamic gliomas (OPHGs), neoplastic lesions that are mainly low-grade gliomas with predominance of pilocytic astrocytomas. They typically occur more frequently in children, but arise also in adults. While some tumors affect the optic nerve alone, the majority of them invade the hypothalamus and optic chiasm as well as adjacent structures. According to the pertinent literature, most authors consider extensive or curative tumor resection not feasible because of high risk for visual loss or severe hypothalamic side effects. Therefore, radiochemotherapy is a widely used modality to treat these challenging lesions. The authors of the present article describe a different strategy of selecting and treating surgically patients with OPHG. Similar to their management of low-grade gliomas in other intracranial location, they have treated a number of OPHGs microsurgically with curative intention. The present patient series comprises 56 individuals (42 pediatric and 14 adult patients). The authors achieved microsurgical gross total (99-100% tumor volume reduction) and near total tumor resection (90-98% volume reduction) in 42 patients (75.0%). There was no surgical mortality, and the rate of complications was low. Postoperatively, the patient's visual and endocrine function remained either intact or at a very satisfactory level in the vast majority of cases. These results differ from those found in previous publications dealing with OPHGs. In the author's experience, proper patient selection played an important role in achieving a good outcome. They conclude that microsurgical management should be considered an important part of the treatment plan in OPHGs. Patients should undergo surgery in an early stage before irreversible symptoms have occurred, and gross total tumor resection should be attempted in well-selected cases. Intentional partial OPHG resection and repeat surgery may help prolonging the symptom-free and tumor progression-free intervals.

本文概述了视神经通路下丘脑胶质瘤(OPHGs),肿瘤病变主要是低级别胶质瘤,以毛细胞星形细胞瘤为主。它们通常更常发生在儿童身上,但也会发生在成人身上。虽然有些肿瘤仅影响视神经,但大多数肿瘤侵犯下丘脑和视交叉以及邻近结构。根据相关文献,大多数作者认为广泛或根治性肿瘤切除是不可行的,因为有可能造成视力丧失或严重的下丘脑副作用。因此,放化疗是一种广泛使用的方式来治疗这些具有挑战性的病变。本文的作者描述了一种不同的选择和治疗手术患者的策略。与其他颅内位置的低级别胶质瘤的治疗方法类似,他们用显微外科手术治疗了许多ophg,目的是治愈。目前的患者系列包括56名个体(42名儿科患者和14名成人患者)。作者在42例(75.0%)患者中实现了显微外科手术总体(肿瘤体积缩小99-100%)和近全部肿瘤切除(肿瘤体积缩小90-98%)。无手术死亡,并发症发生率低。术后,绝大多数患者的视觉和内分泌功能保持完整或处于非常满意的水平。这些结果不同于先前关于ophg的出版物。根据笔者的经验,正确的患者选择在取得良好的结果中起着重要的作用。他们得出结论,显微外科治疗应被视为ophg治疗计划的重要组成部分。患者应在出现不可逆症状之前进行早期手术,并在精心挑选的病例中尝试肿瘤全切除术。有意部分切除和重复手术可能有助于延长无症状和肿瘤无进展的时间间隔。
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引用次数: 0
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Advances and technical standards in neurosurgery
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