Newly Diagnosed Diabetes Mellitus During COVID-19: The New Pandemic - A Literature Review.

IF 3.6 Q2 INFECTIOUS DISEASES Current Tropical Medicine Reports Pub Date : 2022-01-01 DOI:10.1007/s40475-022-00268-3

Nicole Knebusch Toriello, Natalia María Prato Alterio, Lourdes María Ramírez Villeda

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引用次数: 2

Abstract

Purpose of review: Coronavirus disease 2019 (COVID-19) has caused a spike in newly diagnosed diabetes mellitus (NDDM). NDDM and COVID-19 infection are not well established as a cause-and-effect relationship; hence, the present review aims to define the underlying causes and consequences of COVID-19 infection in relation to the condition.

Recent findings: β-Cells are infiltrated by SARS-CoV-2, causing glycometabolic dysfunction and insulin dysregulation. The disease causes systemic inflammation and pro-inflammatory cytokines, as well as hormonal changes that lead to insulin resistance and hyperglycemia that are difficult to manage. As a result of NDDM, complications related to COVID-19 infection become more severe.

Summary: NDDM related to COVID-19 infection complicates hospitalization outcomes and adversely affects quality of life in patients. There are many possible causes and consequences associated with NDDM, but for establishing preventive measures and treatments for NDDM, more evidence regarding its epidemiology, physiopathology, etiology, and nutritional aspects is required.

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新诊断的糖尿病在COVID-19:新的大流行-文献综述。

综述目的:2019冠状病毒病(COVID-19)导致新诊断糖尿病(NDDM)激增。NDDM与COVID-19感染的因果关系尚不明确;因此，本综述旨在确定COVID-19感染与该病相关的潜在原因和后果。最新发现:β-细胞被SARS-CoV-2浸润，导致糖代谢功能障碍和胰岛素失调。这种疾病会导致全身性炎症和促炎性细胞因子，以及导致胰岛素抵抗和高血糖的激素变化，这些都很难控制。由于NDDM，与COVID-19感染相关的并发症变得更加严重。总结:与COVID-19感染相关的NDDM使住院结果复杂化，并对患者的生活质量产生不利影响。与NDDM相关的可能原因和后果有许多，但为了建立NDDM的预防措施和治疗方法，需要更多关于其流行病学，生理病理学，病因学和营养方面的证据。

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来源期刊

Current Tropical Medicine Reports Medicine-Infectious Diseases

CiteScore

9.30

自引率

1.90%

发文量

期刊介绍： Current Tropical Medicine Reports provides expert views on recent advances in the field of tropical medicine in a clear and readable form. This journal offers reviews by domestic and international contributors that highlight the most important, recent papers and findings related to this specific field. We accomplish this by appointing renowned leaders in major tropical medicine subject areas to select topics addressing virology, bacteriology, parasitology, entomology, immunology, cell and molecular biology, epidemiology, ecology, behavioral science and clinical medicine for review by experts who assess the latest developments and highlight significant papers published over the last few years on their topics. These review articles also stress recently published papers of importance in the references, which are accompanied by annotations explaining their importance. In addition to these Section Editors, our international Editorial Board ensures our journal upholds its standards.