Pub Date : 2024-09-01Epub Date: 2024-06-19DOI: 10.1007/s40475-024-00323-1
Dillon T Wademan, Jean Hunleth, Musonda Simwinga, Tahiya Mahbub, Sarah Bernays, Graeme Hoddinott, Amrita Daftary
Purpose of review: Despite evidence of the benefits of including children's voices in global health research, they continue to be underrepresented. Implementation of how to include children's voices appears to remain an obstacle to their inclusion in global health research. In this manuscript, we present an epistemological frame that advocates children as experts of their own experiences and knowledge-bearers. Then we provide four case studies, to illustrate ongoing efforts to build equity in the design and execution of paediatric health research.
Recent findings: Ensuring children's equitable inclusion requires recognizing them as active participants in their health and wellbeing, and empowering them to employ their agency in all interactions with researchers, while recognizing the dialogical nature of those interactions. Successfully involving children in global health research can lead to important psychosocial and clinical insights, that could be leveraged to inform future treatment and care practices.
Summary: We present four case studies describing the inclusion of children in research and research development related to prevention, treatment and/or care of chronic and acute diseases (tuberculosis, HIV, cervical and other forms of cancer) in a number of global settings including India, Philippines, South Africa, United States, Zambia. The exemplars detail novel applications of a diversity of arts-based methods that are rooted in frameworks for participatory action research. They highlight the need to invest funds, training, time and resources for early and sustained engagement with children throughout the research process. We conclude by offering principles for equitably engaging children in global health research.
{"title":"Including the voice of children <15-years-old in paediatric global health research.","authors":"Dillon T Wademan, Jean Hunleth, Musonda Simwinga, Tahiya Mahbub, Sarah Bernays, Graeme Hoddinott, Amrita Daftary","doi":"10.1007/s40475-024-00323-1","DOIUrl":"10.1007/s40475-024-00323-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>Despite evidence of the benefits of including children's voices in global health research, they continue to be underrepresented. Implementation of how to include children's voices appears to remain an obstacle to their inclusion in global health research. In this manuscript, we present an epistemological frame that advocates children as experts of their own experiences and knowledge-bearers. Then we provide four case studies, to illustrate ongoing efforts to build equity in the design and execution of paediatric health research.</p><p><strong>Recent findings: </strong>Ensuring children's equitable inclusion requires recognizing them as active participants in their health and wellbeing, and empowering them to employ their agency in all interactions with researchers, while recognizing the dialogical nature of those interactions. Successfully involving children in global health research can lead to important psychosocial and clinical insights, that could be leveraged to inform future treatment and care practices.</p><p><strong>Summary: </strong>We present four case studies describing the inclusion of children in research and research development related to prevention, treatment and/or care of chronic and acute diseases (tuberculosis, HIV, cervical and other forms of cancer) in a number of global settings including India, Philippines, South Africa, United States, Zambia. The exemplars detail novel applications of a diversity of arts-based methods that are rooted in frameworks for participatory action research. They highlight the need to invest funds, training, time and resources for early and sustained engagement with children throughout the research process. We conclude by offering principles for equitably engaging children in global health research.</p>","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"11 3","pages":"126-134"},"PeriodicalIF":3.6,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11433855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142355847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-04DOI: 10.1007/s40475-023-00310-y
Sasipha Hokeness, Faye Lanni, Jessica Glycenfer, A. Obregón-Henao, M. Henao-Tamayo
{"title":"Tuberculous Meningitis: an Update on the Pathogenesis and Neuroimmunology","authors":"Sasipha Hokeness, Faye Lanni, Jessica Glycenfer, A. Obregón-Henao, M. Henao-Tamayo","doi":"10.1007/s40475-023-00310-y","DOIUrl":"https://doi.org/10.1007/s40475-023-00310-y","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"60 7","pages":"1-10"},"PeriodicalIF":5.4,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139384548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-13DOI: 10.1007/s40475-023-00311-x
Jessica V. Mendoza, L. Harburguer, Paula V. Gonzalez
{"title":"Aliphatic Lactones of Natural Origin: Their Toxicological and Behavioral Effects as a Possible Control Strategy for Medical Importance Mosquitoes","authors":"Jessica V. Mendoza, L. Harburguer, Paula V. Gonzalez","doi":"10.1007/s40475-023-00311-x","DOIUrl":"https://doi.org/10.1007/s40475-023-00311-x","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"6 1","pages":""},"PeriodicalIF":5.4,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139003662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.1007/s40475-023-00308-6
Carlos Ramiro Silva-Ramos, Julián A. Mejorano-Fonseca, Marylin Hidalgo, A. J. Rodriguez-Morales, Álvaro A. Faccini-Martínez
{"title":"Clinical, Epidemiological, and Laboratory Features of Mayaro Virus Infection: a Systematic Review","authors":"Carlos Ramiro Silva-Ramos, Julián A. Mejorano-Fonseca, Marylin Hidalgo, A. J. Rodriguez-Morales, Álvaro A. Faccini-Martínez","doi":"10.1007/s40475-023-00308-6","DOIUrl":"https://doi.org/10.1007/s40475-023-00308-6","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"43 1","pages":""},"PeriodicalIF":5.4,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139230977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-23DOI: 10.1007/s40475-023-00300-0
Christian Olivo-Freites, Hendrik Sy, Jorge Cardenas-Alvarez, Franklyn Vega-Batista, A. Henao-Martínez
{"title":"Trypanosoma cruzi Central Nervous System Infection—Pathogenesis, Clinical Manifestations, Diagnosis, and Treatment","authors":"Christian Olivo-Freites, Hendrik Sy, Jorge Cardenas-Alvarez, Franklyn Vega-Batista, A. Henao-Martínez","doi":"10.1007/s40475-023-00300-0","DOIUrl":"https://doi.org/10.1007/s40475-023-00300-0","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"180 ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-21DOI: 10.1007/s40475-023-00309-5
Eduardo A Fernández C, Peter Youssef
{"title":"Snakebites in the Americas: a Neglected Problem in Public Health","authors":"Eduardo A Fernández C, Peter Youssef","doi":"10.1007/s40475-023-00309-5","DOIUrl":"https://doi.org/10.1007/s40475-023-00309-5","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"25 3","pages":""},"PeriodicalIF":5.4,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139252737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-17DOI: 10.1007/s40475-023-00302-y
Michael D Lum, Olga Syritsyna, Eric Spitzer, Luis A. Marcos
{"title":"Neurologic Manifestations of Tick-Borne Diseases Transmitted by Deer Ticks (Ixodes scapularis) in the USA","authors":"Michael D Lum, Olga Syritsyna, Eric Spitzer, Luis A. Marcos","doi":"10.1007/s40475-023-00302-y","DOIUrl":"https://doi.org/10.1007/s40475-023-00302-y","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"35 5","pages":""},"PeriodicalIF":5.4,"publicationDate":"2023-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139264525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-11DOI: 10.1007/s40475-023-00301-z
Héctor Rivera-Villegas, María Fernanda Vargas-Morales, Juan Sierra-Madero
{"title":"CNS Infections in Patients Living with HIV/AIDS","authors":"Héctor Rivera-Villegas, María Fernanda Vargas-Morales, Juan Sierra-Madero","doi":"10.1007/s40475-023-00301-z","DOIUrl":"https://doi.org/10.1007/s40475-023-00301-z","url":null,"abstract":"","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"52 14","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135043131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-03DOI: 10.1007/s40475-023-00293-w
Juliet C. Stephenson, Dominic R. Garza, Tejas Bouklas
Abstract Purpose of Review Candida auris is a multi-drug-resistant pathogen with many phenotypic variations that contribute to its pathogenicity. This review aims to characterize its phenotypic heterogeneity while highlighting the variants that should be prioritized in future research to advance therapies against C. auris . Recent Findings As the Earth warms, fungi like Candida experience selective pressure to tolerate these higher temperatures and become the few fungal species capable of successfully colonizing the host. The most recent of these is C. auris , which has become an acute concern due to its rapid emergence, high mortality rate, and resistance to all known classes of antifungals. Summary Several studies have contributed rapidly to our general understanding of C. auris , but not enough has been experimentally verified on its morphological variation and its ability to maintain a successful commensal lifestyle on the human skin. Because of its distinct phenotypic variations compared to other fungal species, especially under the selective pressures of its host, C. auris presents a unique opportunity to identify unique targets and strategies to contribute to the antifungal pipeline and control emergent pathogens.
{"title":"A Fungus for Our Time: Candida auris Emerges into the Anthropocene","authors":"Juliet C. Stephenson, Dominic R. Garza, Tejas Bouklas","doi":"10.1007/s40475-023-00293-w","DOIUrl":"https://doi.org/10.1007/s40475-023-00293-w","url":null,"abstract":"Abstract Purpose of Review Candida auris is a multi-drug-resistant pathogen with many phenotypic variations that contribute to its pathogenicity. This review aims to characterize its phenotypic heterogeneity while highlighting the variants that should be prioritized in future research to advance therapies against C. auris . Recent Findings As the Earth warms, fungi like Candida experience selective pressure to tolerate these higher temperatures and become the few fungal species capable of successfully colonizing the host. The most recent of these is C. auris , which has become an acute concern due to its rapid emergence, high mortality rate, and resistance to all known classes of antifungals. Summary Several studies have contributed rapidly to our general understanding of C. auris , but not enough has been experimentally verified on its morphological variation and its ability to maintain a successful commensal lifestyle on the human skin. Because of its distinct phenotypic variations compared to other fungal species, especially under the selective pressures of its host, C. auris presents a unique opportunity to identify unique targets and strategies to contribute to the antifungal pipeline and control emergent pathogens.","PeriodicalId":37441,"journal":{"name":"Current Tropical Medicine Reports","volume":"130 S208","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135818954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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