Physician frontline treatment preferences for stage III/IV classic Hodgkin lymphoma: the real-world US CONNECT study.

IF 3 4区 医学 Q2 ONCOLOGY Future oncology Pub Date : 2024-04-01 Epub Date: 2023-09-04 DOI:10.2217/fon-2023-0358
Andrew M Evens, Kristina S Yu, Nicholas Liu, Andy Surinach, Katherine Holmes, Carlos Flores, Michelle A Fanale, Darcy R Flora, Susan K Parsons
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Abstract

Aim: To understand US physicians' frontline (1L) treatment preferences/decision-making for stage III/IV classic Hodgkin lymphoma (cHL). Materials & methods: Medical oncologists and/or hematologists (≥2 years' practice experience) who treat adults with stage III/IV cHL were surveyed online (October-November 2020). Results: Participants (n = 301) most commonly considered trial efficacy/safety data and national guidelines when selecting 1L cHL treatments. Most physicians (91%) rated overall survival (OS) as the most essential attribute when selecting 1L treatment. Variability was seen among regimen selection for hypothetical newly diagnosed patients, with OS cited as the most common reason for regimen selection. Conclusion: While treatment selection varied based on patient characteristics, US physicians consistently cited OS as the top factor considered when selecting a 1L treatment for cHL.

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医生对 III/IV 期典型霍奇金淋巴瘤一线治疗的偏好:真实世界美国 CONNECT 研究。
目的:了解美国医生对 III/IV 期典型霍奇金淋巴瘤 (cHL) 的一线 (1L) 治疗偏好/决策。材料与方法:对治疗成人 III/IV 期 cHL 的肿瘤内科医生和/或血液内科医生(≥2 年执业经验)进行在线调查(2020 年 10 月至 11 月)。调查结果显示参与者(n = 301)在选择 1L cHL 治疗方法时最常考虑的是试验疗效/安全性数据和国家指南。大多数医生(91%)认为总生存期(OS)是选择 1L 治疗时最重要的因素。为假定的新诊断患者选择治疗方案时存在差异,OS 是选择治疗方案的最常见原因。结论虽然治疗方案的选择因患者特征而异,但美国医生在为 cHL 选择 1L 治疗方案时,始终将 OS 作为首要考虑因素。
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来源期刊
Future oncology
Future oncology ONCOLOGY-
CiteScore
5.40
自引率
3.00%
发文量
335
审稿时长
4-8 weeks
期刊介绍: Future Oncology (ISSN 1479-6694) provides a forum for a new era of cancer care. The journal focuses on the most important advances and highlights their relevance in the clinical setting. Furthermore, Future Oncology delivers essential information in concise, at-a-glance article formats - vital in delivering information to an increasingly time-constrained community. The journal takes a forward-looking stance toward the scientific and clinical issues, together with the economic and policy issues that confront us in this new era of cancer care. The journal includes literature awareness such as the latest developments in radiotherapy and immunotherapy, concise commentary and analysis, and full review articles all of which provide key findings, translational to the clinical setting.
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