Cell viability and physicochemical effects of different concentrations of bismuth trioxide in a mineral trioxide aggregate cement.

IF 1.9 4区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Journal of oral science Pub Date : 2023-01-11 DOI:10.2334/josnusd.22-0139

Karla Padrón-Alvarado, Laura A García-Mendoza, Juana P Ramírez-Ortega, Jacqueline A Rodríguez-Chavéz, María D L A Moyaho-Bernal, Juan A Arreguín-Cano, Lia A Hoz-Rodríguez, Ana Wintergerst, Jesús A Arenas-Alatorre, Abigailt Flores-Ledesma

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引用次数: 1

Abstract

Purpose: To evaluate the effect of three concentrations of bismuth trioxide (Bi₂O₃) on the biological and physicochemical properties of an experimental mineral trioxide aggregate-type (MTA-type) cement at different time points.

Methods: Three experimental groups with white Portland cement containing 15, 20, or 25 wt% of Bi₂O₃ were assessed. Cellular proliferation in human periodontal ligament fibroblasts was evaluated with an MTT assay. Radiopacity, dimensional stability, pH, and compressive strength were evaluated at different time points.

Results: Bismuth trioxide induced cell proliferation in the Bi15 and Bi25 groups in a time-dependent manner; pH was similar in all groups. Compressive strength was associated with time and bismuth concentration. Bi25 had significantly contracted at day 7 and expanded at day 14 (ANOVA P < 0.05, post hoc Tukey test P < 0.05).

Conclusion: A higher Bi₂O₃ concentration had a negative effect on the physical properties of the cement at all time points.

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不同浓度的三氧化二铋在矿物三氧化二骨料水泥中的细胞活力和物理化学效应。

目的:研究不同浓度的三氧化铋(Bi2O3)在不同时间点对实验性三氧化铋骨料型(mta型)水泥的生物和物理化学性能的影响。方法:使用含有15%、20%或25% Bi2O3的白色硅酸盐水泥进行三个实验组的评估。用MTT法评价人牙周韧带成纤维细胞的细胞增殖。在不同时间点评估放射不透明度、尺寸稳定性、pH值和抗压强度。结果:三氧化二铋诱导Bi15和Bi25组细胞增殖呈时间依赖性;各组pH值相近。抗压强度与时间和铋浓度有关。Bi25在第7天显著收缩，第14天显著扩张(方差分析P < 0.05，事后Tukey检验P < 0.05)。结论:较高的Bi2O3浓度对水泥各时间点的物理性能均有不利影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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