A Retrospective Analysis of the Application of the Newly Proposed International System for Reporting Serous Fluid Cytopathology on Serous Effusion Specimens: An Institutional Experience.

IF 1.6 4区 医学 Q3 PATHOLOGY Acta Cytologica Pub Date : 2023-01-01 DOI:10.1159/000527398
Priyadarshini Kumaraswamy Rajeswaran, Vidhyalakshmi Srinivasan, Swaathi Shri Venkatasubramanian Mahesh, Arsha Usha Ashok
{"title":"A Retrospective Analysis of the Application of the Newly Proposed International System for Reporting Serous Fluid Cytopathology on Serous Effusion Specimens: An Institutional Experience.","authors":"Priyadarshini Kumaraswamy Rajeswaran,&nbsp;Vidhyalakshmi Srinivasan,&nbsp;Swaathi Shri Venkatasubramanian Mahesh,&nbsp;Arsha Usha Ashok","doi":"10.1159/000527398","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The International Academy of Cytology and the American Society of Cytopathology recently proposed the International System for Reporting Serous Fluid Cytology (ISRSFC) to standardize serous fluid cytopathology reporting and guide further clinical management. The current study aimed to assess the feasibility of utilizing ISRSFC reporting categories for serous fluids, estimate the risk of malignancy (ROM) of each category, and scrutinize if the management protocols followed in our institution are as per the ISRFSFC recommendations.</p><p><strong>Methods: </strong>All pleural, peritoneal, and pericardial effusions submitted for evaluation at our institute between January 2021 and December 2021 were retrieved. All these cases were reviewed and re-categorized into one of the five categories proposed by the ISRSFC: non-diagnostic (ND), negative for malignancy (NFM), atypia of uncertain significance (AUS), suspicious for malignancy (SFM), and malignant (MAL), and ROM was calculated for each category.</p><p><strong>Results: </strong>The present study examined 596 serous effusions, of which 229 were pleural effusions, 358 were peritoneal effusions, and the remaining nine were pericardial effusions. Among 596 cases, 395 cases had a radiological or histological follow-up. The serous effusion samples were re-categorized as 61 (10.2%) ND, 449 (75.3%) NFM, 47 (7.8%) AUS, 17 (2.9%) SFM, and 22 (3.8%) MAL, and ROM for each above category were 10%, 4.4%, 19%, 83.3%, and 100%, respectively.</p><p><strong>Conclusion: </strong>Categorizing serous effusion cytology samples per the ISRSFC diagnostic categories reduces reporting variability. The ISRSFC provides a standardized format to predict the ROM and thus improves the quality of clinical care.</p>","PeriodicalId":6959,"journal":{"name":"Acta Cytologica","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Cytologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000527398","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 1

Abstract

Introduction: The International Academy of Cytology and the American Society of Cytopathology recently proposed the International System for Reporting Serous Fluid Cytology (ISRSFC) to standardize serous fluid cytopathology reporting and guide further clinical management. The current study aimed to assess the feasibility of utilizing ISRSFC reporting categories for serous fluids, estimate the risk of malignancy (ROM) of each category, and scrutinize if the management protocols followed in our institution are as per the ISRFSFC recommendations.

Methods: All pleural, peritoneal, and pericardial effusions submitted for evaluation at our institute between January 2021 and December 2021 were retrieved. All these cases were reviewed and re-categorized into one of the five categories proposed by the ISRSFC: non-diagnostic (ND), negative for malignancy (NFM), atypia of uncertain significance (AUS), suspicious for malignancy (SFM), and malignant (MAL), and ROM was calculated for each category.

Results: The present study examined 596 serous effusions, of which 229 were pleural effusions, 358 were peritoneal effusions, and the remaining nine were pericardial effusions. Among 596 cases, 395 cases had a radiological or histological follow-up. The serous effusion samples were re-categorized as 61 (10.2%) ND, 449 (75.3%) NFM, 47 (7.8%) AUS, 17 (2.9%) SFM, and 22 (3.8%) MAL, and ROM for each above category were 10%, 4.4%, 19%, 83.3%, and 100%, respectively.

Conclusion: Categorizing serous effusion cytology samples per the ISRSFC diagnostic categories reduces reporting variability. The ISRSFC provides a standardized format to predict the ROM and thus improves the quality of clinical care.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
回顾性分析新提出的浆液细胞病理报告国际系统在浆液标本上的应用:一个机构的经验。
简介:国际细胞学学会和美国细胞病理学学会最近提出了国际浆液细胞学报告系统(ISRSFC),以规范浆液细胞病理学报告并指导进一步的临床管理。本研究旨在评估在浆液中使用ISRSFC报告类别的可行性,估计每个类别的恶性风险(ROM),并审查我们机构所遵循的管理方案是否符合ISRFSFC的建议。方法:检索2021年1月至2021年12月期间在我们研究所提交评估的所有胸膜、腹膜和心包积液。对所有病例进行回顾,并将其重新分类为ISRSFC提出的5类:非诊断性(ND)、恶性阴性(NFM)、意义不确定异型(AUS)、可疑恶性(SFM)和恶性(MAL)之一,并计算每一类的ROM。结果:本研究检查了596例浆液积液,其中229例为胸腔积液,358例为腹膜积液,其余9例为心包积液。在596例病例中,395例进行了放射学或组织学随访。浆液积液样本重新分类为ND 61例(10.2%),NFM 449例(75.3%),AUS 47例(7.8%),SFM 17例(2.9%),MAL 22例(3.8%),ROM分别为10%,4.4%,19%,83.3%和100%。结论:根据ISRSFC诊断分类对浆液积液细胞学样本进行分类可以减少报告的可变性。ISRSFC提供了预测ROM的标准化格式,从而提高了临床护理的质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Acta Cytologica
Acta Cytologica 生物-病理学
CiteScore
3.70
自引率
11.10%
发文量
46
审稿时长
4-8 weeks
期刊介绍: With articles offering an excellent balance between clinical cytology and cytopathology, ''Acta Cytologica'' fosters the understanding of the pathogenetic mechanisms behind cytomorphology and thus facilitates the translation of frontline research into clinical practice. As the official journal of the International Academy of Cytology and affiliated to over 50 national cytology societies around the world, ''Acta Cytologica'' evaluates new and existing diagnostic applications of scientific advances as well as their clinical correlations. Original papers, review articles, meta-analyses, novel insights from clinical practice, and letters to the editor cover topics from diagnostic cytopathology, gynecologic and non-gynecologic cytopathology to fine needle aspiration, molecular techniques and their diagnostic applications. As the perfect reference for practical use, ''Acta Cytologica'' addresses a multidisciplinary audience practicing clinical cytopathology, cell biology, oncology, interventional radiology, otorhinolaryngology, gastroenterology, urology, pulmonology and preventive medicine.
期刊最新文献
Reclassification of urinary cytology according to The Paris System for Reporting Urinary Cytology correlation with histological diagnosis. Cytopathology of a newly described salivary gland neoplasm. A case report of microsecretory adenocarcinoma presenting in the parotid gland. Does The Diagnostic Performance Of The Pathologist On The Indeterminate Categories Of The Bethesda System For Reporting Thyroid Cytopathology Vary Between Pediatric And Adult Patients? Evaluation of a Cytology-Molecular Co-Test in Liquid-Based Cytology-Processed Urine for Defining Indeterminate Categories of the Paris System. Diagnostic and Predictive Immunocytochemistry in Lung Cancer.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1