Jakub Pazdrowski, Pawel Golusinski, Mateusz Szewczyk, Ewa Majchrzak, Aleksandra Dańczak-Pazdrowska, Wojciech Golusiński
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引用次数: 0
Abstract
Purpose: To assess the efficacy of two reconstructive methods: pectoralis major myocutaneous flap and revascularised free flap in salvage surgery for recurrent head and neck cancer.
Patients and methods: We retrospectively analysed 100 cases of patients who had recurrent head and neck cancer and were treated in the Department of Head and Neck Surgery between 2011 and 2021. The study participants were divided into two groups depending on the method of reconstruction: 62 patients who underwent revascularised free flap reconstruction and 38 patients with pectoralis major myocutaneous flap.
Results: In total, flap necrosis was observed in 20 cases, 18 of which were in the group who received revascularised free flaps (29.03%) and 2 in the pectoralis major myocutaneous flap group (5.26%). The OR of flap failure in the free flap group vs. pectoralis major flap group was 7.36 (95% CI 0.85-63.75; p=0.067) In the group who underwent revascularised free flap reconstruction the total surgery time was significantly longer than in the other group (p < 0.0001).
Conclusion: We suggest the advantages of using pectoralis major myocutaneous flaps for recurrent head and cancers, which is of the utmost importance for malnourished patients in poor general health and whose primary treatment comprised of a combination therapy.
目的:探讨胸大肌肌皮瓣和带血运的游离皮瓣在复发性头颈癌手术中的应用效果。患者和方法:我们回顾性分析了2011年至2021年间在头颈外科接受治疗的100例复发性头颈癌患者。根据重建方法的不同,将研究对象分为两组:62例进行了血运重建的游离皮瓣重建,38例进行了胸大肌肌皮瓣重建。结果:皮瓣坏死20例,其中重建游离皮瓣组18例(29.03%),胸大肌肌皮瓣组2例(5.26%)。自由瓣组与胸大肌瓣组皮瓣失败的OR为7.36 (95% CI 0.85-63.75;p=0.067)行血管重建游离皮瓣重建组总手术时间明显长于另一组(p <0.0001)。结论:我们认为应用胸大肌肌皮瓣治疗复发性头癌和恶性肿瘤具有优势,这对于一般健康状况不佳且主要治疗由联合治疗组成的营养不良患者至关重要。