Pub Date : 2024-09-12DOI: 10.5604/01.3001.0054.5661
Maya Madhavan, Muhammad Ibraheem Zaid, Khizer Chaudhary, Chetachi Soribe, Muhammed Jlal Siddiqui, Nabiha Ali, Roisin Rahaman, Helga Brito Lima, Sanya Nair, Nessa Din, Maria Marzec, Maciej J Wróbel
<b>Introduction:</b> Auditory scene analysis refers to the system through which the auditory system distinguishes distinct auditory events and sources to create meaningful auditory information. The exact number of directly perceived auditory stimuli is unknown, studies suggest it may range from 3 to 5. This number differs among individuals, and potentially may indirectly indicate the ability to store and process the complex information, related to the memory load, which is combined with human cognitive processes.<b>Aim:</b> This study aims to further identify and quantify the number of sounds that can be perceived simultaneously in a complex auditory environment.<b>Material and methods:</b> Participants were presented with structured acoustic recordings and were asked to identify the exact number of targeted stimuli heard throughout the test. The experiment was designed to assess the auditory load and determine the maximum number of auditory stimuli that a healthy human can perceive at once.<b>Results:</b> Our study showed that on average, participants could identify up to three sounds at once with accuracy of responses declining progressively for four sounds or more.<b>Conclusions:</b> This study aimed to investigate the human capacity to detect and identify multiple sound signals simultaneously in a noisy environment. By understanding this ability, we sought to assess cognitive reserve in individuals. Our objective was to determine if auditory load could serve as a diagnostic tool for cognitive evaluation. We believe that further research will establish the validity of this approach, and we anticipate that it is only a matter of time before it becomes a viable method for assessing cognitive function.
{"title":"Memory Load Test - A Concept for Cognitive Reserve Evaluation with Auditory Perception.","authors":"Maya Madhavan, Muhammad Ibraheem Zaid, Khizer Chaudhary, Chetachi Soribe, Muhammed Jlal Siddiqui, Nabiha Ali, Roisin Rahaman, Helga Brito Lima, Sanya Nair, Nessa Din, Maria Marzec, Maciej J Wróbel","doi":"10.5604/01.3001.0054.5661","DOIUrl":"https://doi.org/10.5604/01.3001.0054.5661","url":null,"abstract":"<p><p><b>Introduction:</b> Auditory scene analysis refers to the system through which the auditory system distinguishes distinct auditory events and sources to create meaningful auditory information. The exact number of directly perceived auditory stimuli is unknown, studies suggest it may range from 3 to 5. This number differs among individuals, and potentially may indirectly indicate the ability to store and process the complex information, related to the memory load, which is combined with human cognitive processes.<b>Aim:</b> This study aims to further identify and quantify the number of sounds that can be perceived simultaneously in a complex auditory environment.<b>Material and methods:</b> Participants were presented with structured acoustic recordings and were asked to identify the exact number of targeted stimuli heard throughout the test. The experiment was designed to assess the auditory load and determine the maximum number of auditory stimuli that a healthy human can perceive at once.<b>Results:</b> Our study showed that on average, participants could identify up to three sounds at once with accuracy of responses declining progressively for four sounds or more.<b>Conclusions:</b> This study aimed to investigate the human capacity to detect and identify multiple sound signals simultaneously in a noisy environment. By understanding this ability, we sought to assess cognitive reserve in individuals. Our objective was to determine if auditory load could serve as a diagnostic tool for cognitive evaluation. We believe that further research will establish the validity of this approach, and we anticipate that it is only a matter of time before it becomes a viable method for assessing cognitive function.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jarosław Markowski, Anna Długosz-Karbowska, Monika Ciupińska, Wojciech Smółka, Zuzanna Dobrosz, Aleksandra Ślaska-Kaspera, Olga Lesniewska-Skowerska, Wirginia Likus, Klaudia Mazurek
<b>Introduction:</b> Soft tissue sarcomas (STS) constitute about 1-2% of all malignant tumors, with approximately 10% of them located in the head and neck region.<b>Aim:</b> The aim of this study was the assessment of treatment efficiency in head and neck STS of adult patients of the ENT Department of Medical University of Silesia, treated surgically in the period 1980-2023.<b>Materials and methods:</b> Retrospective analysis of 39 patients with the diagnosis of head and neck STS.<b>Results:</b> Histopathological examination showed 21 different types of STS located most commonly in: paranasal sinuses (13 cases), orbital cavity (6 cases), nasal cavity (3 cases), and larynx (3 cases). Other locations: parapharyngeal space, parotid gland, nasal septum, bridge of the nose, soft and hard palate, mandibular mucosa, tongue, auricle, palatine tonsil, and cheek. All those patients underwent chemoradiation as postoperative treatment. Radical surgical procedure was achieved in 32 patients (82%). However, in 11 patients (28%), microscopic examination did not confirm radical resection (R1 - PSM - positive surgical margin). In 7 patients (18%), the surgical procedure turned out to be not radical on macroscopic examination (R2). Dissemination of neoplasms (distant metastases) was found in 7 patients (18%). Five-year survival time without local recurrence was achieved in 25 patients (64%). The most frequent reason for unsuccessful interventions was local recurrence noted in 18 patients (46%), while distant metastases occurred in 9 patients (23%).<b>Conclusions:</b> The basic procedure in the treatment of STS is radical surgery combined with preoperative or postoperative radiotherapy and/or chemotherapy and, in case of a metastasis, surgical removal thereof. Despite the fact that sarcomas are rare tumors, they remain a challenge for head and neck surgery. Recurrence rates and mortality remain high due to the high degree of malignancy.
{"title":"Soft tissue sarcomas of the head and neck region: clinical and histopathological study of 39 patients.","authors":"Jarosław Markowski, Anna Długosz-Karbowska, Monika Ciupińska, Wojciech Smółka, Zuzanna Dobrosz, Aleksandra Ślaska-Kaspera, Olga Lesniewska-Skowerska, Wirginia Likus, Klaudia Mazurek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Introduction:</b> Soft tissue sarcomas (STS) constitute about 1-2% of all malignant tumors, with approximately 10% of them located in the head and neck region.<b>Aim:</b> The aim of this study was the assessment of treatment efficiency in head and neck STS of adult patients of the ENT Department of Medical University of Silesia, treated surgically in the period 1980-2023.<b>Materials and methods:</b> Retrospective analysis of 39 patients with the diagnosis of head and neck STS.<b>Results:</b> Histopathological examination showed 21 different types of STS located most commonly in: paranasal sinuses (13 cases), orbital cavity (6 cases), nasal cavity (3 cases), and larynx (3 cases). Other locations: parapharyngeal space, parotid gland, nasal septum, bridge of the nose, soft and hard palate, mandibular mucosa, tongue, auricle, palatine tonsil, and cheek. All those patients underwent chemoradiation as postoperative treatment. Radical surgical procedure was achieved in 32 patients (82%). However, in 11 patients (28%), microscopic examination did not confirm radical resection (R1 - PSM - positive surgical margin). In 7 patients (18%), the surgical procedure turned out to be not radical on macroscopic examination (R2). Dissemination of neoplasms (distant metastases) was found in 7 patients (18%). Five-year survival time without local recurrence was achieved in 25 patients (64%). The most frequent reason for unsuccessful interventions was local recurrence noted in 18 patients (46%), while distant metastases occurred in 9 patients (23%).<b>Conclusions:</b> The basic procedure in the treatment of STS is radical surgery combined with preoperative or postoperative radiotherapy and/or chemotherapy and, in case of a metastasis, surgical removal thereof. Despite the fact that sarcomas are rare tumors, they remain a challenge for head and neck surgery. Recurrence rates and mortality remain high due to the high degree of malignancy.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katarzyna Bieńkowska, Barbara Kostecka, Mirosław Ząbek, Andrzej Kokoszka, Sebastian Dzierzęcki, Ewelina Cichoń, Grzegorz Turek
<b>Introduction:</b> The Glasgow Benefit Inventory (GBI) is one of questionnaires for the measurement of treatment success, which is widely used in patients after vestibular schwannoma treatment.<b>Aim:</b> This study aimed to adapt the GBI originally written in English to Polish conditions and to evaluate its psychometric properties.<b>Material and methods:</b> The Polish version of the GBI used in this study was prepared by a bilingual translator, and its accuracy was ensured by back-translation. To identify the structure of the Polish version of the GBI, exploratory factor analysis was performed. The reliability was determined using Cronbach's α. To verify the validity, correlation analysis was conducted between the domains of GBI and other questionnaires.<b>Results:</b> The results of confirmatory factor analysis indicated that the original 3-factor model is not a good fit for the data. The exploratory factor analysis was performed and identified 4 factors. The total variance of the 4-factor solution was 66.25%. The Cronbach's α calculated for the total GBI reached 0.91. Our analysis confirmed significant weak or moderate correlations between tools for the measurement of general QoL (AQoL-8D: r = 0.411; p = 0.000) and health-related QoL (PANQOL: r = 0.367; p = 0.000; a tool dedicated for patients with VS), well-being (WHO-5: r = 0.432; p = 0.000), hearing and tinnitus (STS: r = -0.217; p = 0.016).<b>Conclusions:</b> This study reports the first adaptation of the GBI for patients with VS to Polish conditions. The results demonstrated that the Polish version of the GBI is a reliable and valid questionnaire that can be used to measure treatment success.
{"title":"Polish cross-cultural adaptation of the Glasgow Benefit Inventory as an instrument for the post-intervention measurement of change after Gamma Knife treatment.","authors":"Katarzyna Bieńkowska, Barbara Kostecka, Mirosław Ząbek, Andrzej Kokoszka, Sebastian Dzierzęcki, Ewelina Cichoń, Grzegorz Turek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Introduction:</b> The Glasgow Benefit Inventory (GBI) is one of questionnaires for the measurement of treatment success, which is widely used in patients after vestibular schwannoma treatment.<b>Aim:</b> This study aimed to adapt the GBI originally written in English to Polish conditions and to evaluate its psychometric properties.<b>Material and methods:</b> The Polish version of the GBI used in this study was prepared by a bilingual translator, and its accuracy was ensured by back-translation. To identify the structure of the Polish version of the GBI, exploratory factor analysis was performed. The reliability was determined using Cronbach's α. To verify the validity, correlation analysis was conducted between the domains of GBI and other questionnaires.<b>Results:</b> The results of confirmatory factor analysis indicated that the original 3-factor model is not a good fit for the data. The exploratory factor analysis was performed and identified 4 factors. The total variance of the 4-factor solution was 66.25%. The Cronbach's α calculated for the total GBI reached 0.91. Our analysis confirmed significant weak or moderate correlations between tools for the measurement of general QoL (AQoL-8D: r = 0.411; p = 0.000) and health-related QoL (PANQOL: r = 0.367; p = 0.000; a tool dedicated for patients with VS), well-being (WHO-5: r = 0.432; p = 0.000), hearing and tinnitus (STS: r = -0.217; p = 0.016).<b>Conclusions:</b> This study reports the first adaptation of the GBI for patients with VS to Polish conditions. The results demonstrated that the Polish version of the GBI is a reliable and valid questionnaire that can be used to measure treatment success.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Rzepakowska, Aleksandra Borowy, Eryk Siedlecki, Marta Wolszczak, Katarzyna Radomska
<b>Introduction:</b> More than 5% of the world's population experience hearing impairment. The most common form is presbycusis (age-related hearing loss; ARHL). It affects almost one in three people over the age of 65. The hair cells of the cochlea play an important role in the process of sound registration. Genetic mutations, aging and environmental factors can cause damage that contributes to the hearing loss.<b>Methods and results:</b> The currently explored research directions include drug treatments, gene therapies, and stem cell therapies. To date, no significant differences in the therapeutic effect depending on the route of corticosteroid administration have been demonstrated in patients with moderate to severe hearing loss. New dexamethasone-containing hydrogel formulations, as well as lipid formulations, thermosensitive polymers, and nanoparticles, have been developed to achieve high drug concentrations in the inner ear structures. Otoprotective effects of antioxidants or substances that modify the toxic effects of e.g. cisplatin, are also being studied. Attempts at auditory cells' regeneration seem promising in hearing loss research. Substances that regulate the central mechanisms of the Notch and Wnt pathways are being explored to this end. The genetic determinants of presbycusis suggest that interference at the level of specific genes may be a promising option for the treatment of this condition. With the CRISPR/Cas9 technology, the functions of inner ear genes can be effectively studied by disrupting normal gene alleles. The CRISPR/Cas9 complexes developed to target specific genes are delivered using cationic lipids, proteins, and viral vectors. They are then transported through the round window membrane by diffusion, without the need to surgically disrupt the inner ear. The potential of using antisense oligonucleotides to treat hereditary deafness caused by hair cell degeneration has also been established. Another research direction is related to stem cells being used for the development of in vitro 3D models of the human inner ear. Studies are also pursued to identify the mechanisms underlying the formation of cochlear organoids from pluripotent cells as well as determine the critical time points and events for cochlear sensory epithelial development and targeted hair cell differentiation.<b>Conclusions:</b> In summary, significant progress has been made over the past decade in the search for novel therapies for sensory hearing loss. This line of research remains an ambitious and important area for further exploration.
{"title":"Contemporary directions in the therapy of sensory hearing loss.","authors":"Anna Rzepakowska, Aleksandra Borowy, Eryk Siedlecki, Marta Wolszczak, Katarzyna Radomska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><b>Introduction:</b> More than 5% of the world's population experience hearing impairment. The most common form is presbycusis (age-related hearing loss; ARHL). It affects almost one in three people over the age of 65. The hair cells of the cochlea play an important role in the process of sound registration. Genetic mutations, aging and environmental factors can cause damage that contributes to the hearing loss.<b>Methods and results:</b> The currently explored research directions include drug treatments, gene therapies, and stem cell therapies. To date, no significant differences in the therapeutic effect depending on the route of corticosteroid administration have been demonstrated in patients with moderate to severe hearing loss. New dexamethasone-containing hydrogel formulations, as well as lipid formulations, thermosensitive polymers, and nanoparticles, have been developed to achieve high drug concentrations in the inner ear structures. Otoprotective effects of antioxidants or substances that modify the toxic effects of e.g. cisplatin, are also being studied. Attempts at auditory cells' regeneration seem promising in hearing loss research. Substances that regulate the central mechanisms of the Notch and Wnt pathways are being explored to this end. The genetic determinants of presbycusis suggest that interference at the level of specific genes may be a promising option for the treatment of this condition. With the CRISPR/Cas9 technology, the functions of inner ear genes can be effectively studied by disrupting normal gene alleles. The CRISPR/Cas9 complexes developed to target specific genes are delivered using cationic lipids, proteins, and viral vectors. They are then transported through the round window membrane by diffusion, without the need to surgically disrupt the inner ear. The potential of using antisense oligonucleotides to treat hereditary deafness caused by hair cell degeneration has also been established. Another research direction is related to stem cells being used for the development of in vitro 3D models of the human inner ear. Studies are also pursued to identify the mechanisms underlying the formation of cochlear organoids from pluripotent cells as well as determine the critical time points and events for cochlear sensory epithelial development and targeted hair cell differentiation.<b>Conclusions:</b> In summary, significant progress has been made over the past decade in the search for novel therapies for sensory hearing loss. This line of research remains an ambitious and important area for further exploration.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.5604/01.3001.0054.4820
Marcin Jadczak, Sandra Krzywdzińska, Dariusz Jurkiewicz
<b>Introduction:</b> Rhinoseptoplasty procedures are focused not only on the aesthetic but also on the functional aspects. Surgical outcomes have to be evaluated in each patient. To date, the Polish literature has lacked a tool facilitating simultaneous assessment of rhinoseptoplasty's impact on both the external appearance and functionality of the nose.<b>Aim:</b> The aim of this study was to translate, adapt, and validate the Polish version of the original SCHNOS (Standardized Cosmesis and Health Nasal Outcomes Survey) questionnaire as used for the assessment of the functional and aesthetic outcomes in patients after rhinoplasty.<b>Materials and methods:</b> A total of 31 subjects (N = 24 [77.4%] women and N = 7 men [22.6%]) aged 19 through 55 years (M = 31.32; SD = 8.50) participated in the study. The SCHNOS questionnaire was translated in accordance with international guidelines. The psychometric accuracy of translation was tested in native speakers of Polish. The authors measured the internal consistency, correlatability, and repeatability of the instrument to determine its validity. The data were subjected to statistical analysis.<b>Results:</b> The confirmatory factor analysis confirmed the two-factor structure of the scale. The satisfactory reliability amounted to 0.888 [95% CI: 0.804-0.940] for the SCHNOS-O and 0.883 [95% CI 0.795-0.937] for the SCHNOS-C scale. Differential accuracy was confirmed by AVE values of > 0.5 as well as by correlation of the results with the Rhinoplasty Outcome Evaluation (ROE) questionnaire scores.<b>Conclusions:</b> The SCHNOS questionnaire has been translated, adapted, and validated for use in the Polish-speaking population. The tool was found to be relevant and reliable.
{"title":"Polish Translation and Validation of the SCHNOS (Standardized Cosmesis and Health Nasal Outcomes Survey) Questionnaire.","authors":"Marcin Jadczak, Sandra Krzywdzińska, Dariusz Jurkiewicz","doi":"10.5604/01.3001.0054.4820","DOIUrl":"https://doi.org/10.5604/01.3001.0054.4820","url":null,"abstract":"<p><p><b>Introduction:</b> Rhinoseptoplasty procedures are focused not only on the aesthetic but also on the functional aspects. Surgical outcomes have to be evaluated in each patient. To date, the Polish literature has lacked a tool facilitating simultaneous assessment of rhinoseptoplasty's impact on both the external appearance and functionality of the nose.<b>Aim:</b> The aim of this study was to translate, adapt, and validate the Polish version of the original SCHNOS (Standardized Cosmesis and Health Nasal Outcomes Survey) questionnaire as used for the assessment of the functional and aesthetic outcomes in patients after rhinoplasty.<b>Materials and methods:</b> A total of 31 subjects (N = 24 [77.4%] women and N = 7 men [22.6%]) aged 19 through 55 years (M = 31.32; SD = 8.50) participated in the study. The SCHNOS questionnaire was translated in accordance with international guidelines. The psychometric accuracy of translation was tested in native speakers of Polish. The authors measured the internal consistency, correlatability, and repeatability of the instrument to determine its validity. The data were subjected to statistical analysis.<b>Results:</b> The confirmatory factor analysis confirmed the two-factor structure of the scale. The satisfactory reliability amounted to 0.888 [95% CI: 0.804-0.940] for the SCHNOS-O and 0.883 [95% CI 0.795-0.937] for the SCHNOS-C scale. Differential accuracy was confirmed by AVE values of > 0.5 as well as by correlation of the results with the Rhinoplasty Outcome Evaluation (ROE) questionnaire scores.<b>Conclusions:</b> The SCHNOS questionnaire has been translated, adapted, and validated for use in the Polish-speaking population. The tool was found to be relevant and reliable.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.5604/01.3001.0054.5437
Grzegorz Turek, Adrian Drożdż, Sebastian Dzierzęcki, Karolina Dżaman, Mariusz Gruda, Justyna Zielińska-Turek, Jan Gajewski, Dominika Bodzak, Mirosław Ząbek
<b>Introduction:</b> The choice of treatment of vestibular schwannoma (VS) depends on several factors, including the tumor size, the patient's age and overall health, and the presence and severity of symptoms.<b>Aim:</b> The aim of the study was to assess the effectiveness of intentional subtotal resection (STR) of tumor followed by Gamma Knife surgery (GKS) in patients with larger VS (Koos 3 and 4).<b>Materials and methods:</b> The retrospective analysis was performed on 18 patients. Data of VS volumes measured in MRI, the facial nerve function assessed in the House-Brackmann scoring system (HB), and the results of audiological examination expressed on the Gardner-Robertson scale (GR) were collected preoperatively, postoperatively, and post-GKS.<b>Results:</b> Preoperatively, the main symptom was hearing loss observed in 13 out of 18 patients. The facial nerve function was assessed as HB 1 in 16, whereas HB 2 in 2 patients. The mean volume of the tumor in the initial MRI amounted to 16.81 cm<sup>3</sup> . Postoperatively, the facial nerve was assessed as HB 1 or 2 in 16, whereas HB 3 in 2 patients. Serviceable hearing was presented by only 4 persons. The Mean diameter of the tumor after subtotal surgery amounted to 3.16 cm<sup>3</sup> , 1.83 cm<sup>3</sup> after GKS, and 1.58 cm<sup>3</sup> at the last follow-up. The facial nerve function and hearing level remained the same as before GKS in all patients.<b>Conclusions:</b> STR followed by GKS can be a safe and effective method of treatment of large VS concerning the functional outcome of the facial nerve and the tumor volume growth control.
{"title":"Subtotal resection of vestibular schwannoma with subsequent Gamma Knife irradiation - tumor growth control, facial and cochlear nerve outcome - preliminary results.","authors":"Grzegorz Turek, Adrian Drożdż, Sebastian Dzierzęcki, Karolina Dżaman, Mariusz Gruda, Justyna Zielińska-Turek, Jan Gajewski, Dominika Bodzak, Mirosław Ząbek","doi":"10.5604/01.3001.0054.5437","DOIUrl":"https://doi.org/10.5604/01.3001.0054.5437","url":null,"abstract":"<p><p><b>Introduction:</b> The choice of treatment of vestibular schwannoma (VS) depends on several factors, including the tumor size, the patient's age and overall health, and the presence and severity of symptoms.<b>Aim:</b> The aim of the study was to assess the effectiveness of intentional subtotal resection (STR) of tumor followed by Gamma Knife surgery (GKS) in patients with larger VS (Koos 3 and 4).<b>Materials and methods:</b> The retrospective analysis was performed on 18 patients. Data of VS volumes measured in MRI, the facial nerve function assessed in the House-Brackmann scoring system (HB), and the results of audiological examination expressed on the Gardner-Robertson scale (GR) were collected preoperatively, postoperatively, and post-GKS.<b>Results:</b> Preoperatively, the main symptom was hearing loss observed in 13 out of 18 patients. The facial nerve function was assessed as HB 1 in 16, whereas HB 2 in 2 patients. The mean volume of the tumor in the initial MRI amounted to 16.81 cm<sup>3</sup> . Postoperatively, the facial nerve was assessed as HB 1 or 2 in 16, whereas HB 3 in 2 patients. Serviceable hearing was presented by only 4 persons. The Mean diameter of the tumor after subtotal surgery amounted to 3.16 cm<sup>3</sup> , 1.83 cm<sup>3</sup> after GKS, and 1.58 cm<sup>3</sup> at the last follow-up. The facial nerve function and hearing level remained the same as before GKS in all patients.<b>Conclusions:</b> STR followed by GKS can be a safe and effective method of treatment of large VS concerning the functional outcome of the facial nerve and the tumor volume growth control.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.5604/01.3001.0054.5438
Przemysław Ryćko, Marek Rogowski
<b>Introduction:</b> Speech audiometry is well established and frequently used test in audiology as well as in cochlear implant recipient's performance evaluation. Expanding indications for cochlear implantation forces use of more refined methods of both assessment and prognosis of outcome of aural rehabilitation. Variability of speech intelligibility tests and materials require standardized protocol facilitating outcome comparison.<b>Aim:</b> Aim of this review paper is analysis of usage of speech audiometry and other speech intelligibility tests and its results reporting in patients with cochlear implant in Poland and in the World.<b>Materials and methods:</b> Protocols of many different domestic and foreign health centers where compared, showing many methodological differences. Selection of literature for analysis was made according to PRISMA algorithm recommendations. Twenty research papers were chosen for review process.<b>Discussion:</b> In many papers we found lack of data regarding methodology of performed tests. Many authors indicate difficulties in comparing results, especially if publication lacks basic technical information. Despite that if right method is applied, results can be compared. In literature only one level of material presentation in test is prevalent. Speech audiometry is significant in exploring connections between multiple pre-op and post-op prognostic aspects of cochlear implantation.<b>Conclusions:</b> Because of variability in presentation and reporting of CI patients outcomes, consensus is needed in area of system facilitating comparison of research results. This may provide simple solution for accurate analysis and choosing right set of data. Schematic of presentation of audiological data in authors health center was proposed as example.
{"title":"Speech recognition and speech audiometry parameters in evaluation of aural rehabilitation progress in cochlear implant patients. Review paper.","authors":"Przemysław Ryćko, Marek Rogowski","doi":"10.5604/01.3001.0054.5438","DOIUrl":"https://doi.org/10.5604/01.3001.0054.5438","url":null,"abstract":"<p><p><b>Introduction:</b> Speech audiometry is well established and frequently used test in audiology as well as in cochlear implant recipient's performance evaluation. Expanding indications for cochlear implantation forces use of more refined methods of both assessment and prognosis of outcome of aural rehabilitation. Variability of speech intelligibility tests and materials require standardized protocol facilitating outcome comparison.<b>Aim:</b> Aim of this review paper is analysis of usage of speech audiometry and other speech intelligibility tests and its results reporting in patients with cochlear implant in Poland and in the World.<b>Materials and methods:</b> Protocols of many different domestic and foreign health centers where compared, showing many methodological differences. Selection of literature for analysis was made according to PRISMA algorithm recommendations. Twenty research papers were chosen for review process.<b>Discussion:</b> In many papers we found lack of data regarding methodology of performed tests. Many authors indicate difficulties in comparing results, especially if publication lacks basic technical information. Despite that if right method is applied, results can be compared. In literature only one level of material presentation in test is prevalent. Speech audiometry is significant in exploring connections between multiple pre-op and post-op prognostic aspects of cochlear implantation.<b>Conclusions:</b> Because of variability in presentation and reporting of CI patients outcomes, consensus is needed in area of system facilitating comparison of research results. This may provide simple solution for accurate analysis and choosing right set of data. Schematic of presentation of audiological data in authors health center was proposed as example.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.5604/01.3001.0054.3355
Marta Pietraszek, Grażyna Greczka, Anna Bartochowska, Wojciech Gawęcki
<b><br>Introduction:</b> The COMQ-12 questionnaire is a tool to assess the quality of life in patients with chronic otitis media in many countries. The questionnaire consists of 12 questions: seven relating to the severity of symptoms, two regarding the impact of the disease on lifestyle and work, two concerning the impact on the need for healthcare, and one is a general question. Each question is rated on a scale from 0 to 5.</br> <b><br>Aim:</b> To present the validation process and the final version of the Polish version of the COMQ-12 questionnaire.</br> <b><br>Material and methods:</b> The Polish version of the COMQ-12 questionnaire was prepared based on an independent translation of the English version by three physicians (two otolaryngology specialists and one physician in the process of specialization in otolaryngology). The questionnaire was validated in a study including 60 participants: 30 patients with chronic otitis media and 30 volunteers without a history of middle ear diseases or hearing disorders. Each participant was asked to complete the COMQ-12 questionnaire twice at an interval of 4 weeks apart. The internal consistency, reliability, and construct validity of the questionnaire were analyzed using Cronbach's alpha and McDonald's omega coefficients, Spearman's rho correlation coefficient, and the Mann-Whitney test, respectively.</br> <b><br>Results:</b> High internal consistency, reliability, and construct validity of the Polish version of the COMQ-12 questionnaire were shown in the course of statistical analysis. The overall internal consistency was 0.95 and 0.97 as assessed by Cronbach's alpha and McDonald's omega coefficients, respectively. Spearman's rho correlation coefficient was above 0.89 for each question. Statistically significant differences in the COMQ-12 total scores were obtained between patients with chronic otitis media and the control group.</br> <b><br>Conclusions:</b> The Polish version of the COMQ-12 questionnaire can be a valuable clinical tool for the assessment of the quality of life in patients suffering from chronic otitis media.</br>.
{"title":"Polish version of the COMQ-12 questionnaire, a new validated tool for the assessment of the quality of life in patients with chronic otitis media.","authors":"Marta Pietraszek, Grażyna Greczka, Anna Bartochowska, Wojciech Gawęcki","doi":"10.5604/01.3001.0054.3355","DOIUrl":"https://doi.org/10.5604/01.3001.0054.3355","url":null,"abstract":"<p><p><b><br>Introduction:</b> The COMQ-12 questionnaire is a tool to assess the quality of life in patients with chronic otitis media in many countries. The questionnaire consists of 12 questions: seven relating to the severity of symptoms, two regarding the impact of the disease on lifestyle and work, two concerning the impact on the need for healthcare, and one is a general question. Each question is rated on a scale from 0 to 5.</br> <b><br>Aim:</b> To present the validation process and the final version of the Polish version of the COMQ-12 questionnaire.</br> <b><br>Material and methods:</b> The Polish version of the COMQ-12 questionnaire was prepared based on an independent translation of the English version by three physicians (two otolaryngology specialists and one physician in the process of specialization in otolaryngology). The questionnaire was validated in a study including 60 participants: 30 patients with chronic otitis media and 30 volunteers without a history of middle ear diseases or hearing disorders. Each participant was asked to complete the COMQ-12 questionnaire twice at an interval of 4 weeks apart. The internal consistency, reliability, and construct validity of the questionnaire were analyzed using Cronbach's alpha and McDonald's omega coefficients, Spearman's rho correlation coefficient, and the Mann-Whitney test, respectively.</br> <b><br>Results:</b> High internal consistency, reliability, and construct validity of the Polish version of the COMQ-12 questionnaire were shown in the course of statistical analysis. The overall internal consistency was 0.95 and 0.97 as assessed by Cronbach's alpha and McDonald's omega coefficients, respectively. Spearman's rho correlation coefficient was above 0.89 for each question. Statistically significant differences in the COMQ-12 total scores were obtained between patients with chronic otitis media and the control group.</br> <b><br>Conclusions:</b> The Polish version of the COMQ-12 questionnaire can be a valuable clinical tool for the assessment of the quality of life in patients suffering from chronic otitis media.</br>.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.5604/01.3001.0054.2567
Agata Szleper, Magdalena Lachowska, Tomasz Wojciechowski, Kazimierz Niemczyk
<b><br>Introduction:</b> Congenital inner ear malformations resulting from embryogenesis may be visualized in radiological scans. Many attempts have been made to describe and classify the defects of the inner ear based on anatomical and radiological findings.</br> <b><br>Aim:</b> The aim was to propose and discuss computed tomography multi-planar and 3D image assessment protocols for detailed analysis of inner ear malformations in patients undergoing cochlear implantation counseling.</br> <b><br>Material and methods:</b> A retrospective analysis of 22 malformed inner ears. CT scans were analyzed using the Multi-Planar Reconstruction (MPR) option and 3D reconstruction.</br> <b><br>Results:</b> The protocol of image interpretation was developed to allow reproducibility for evaluating each set of images. The following malformations were identified: common cavity, cochlear hypoplasia type II, III, and IV, incomplete partition type II and III, and various combinations of vestibule labyrinth malformations. All anomalies have been presented and highlighted in figures with appropriate descriptions for easier identification. Figures of normal inner ears were also included for comparison. 3D reconstructions for each malformation were presented, adding clinical value to the detailed analysis.</br> <b><br>Conclusions:</b> Properly analyzing CT scans in cochlear implantation counseling is a necessary and beneficial tool for appropriate candidate selection and preparation for surgery. As proposed in this study, the unified scans evaluation scheme simplifies the identification of malformations and reduces the risk of omitting particular anomalies. Multi-planar assessment of scans provides most of the necessary details. The 3D reconstruction technique is valuable in addition to diagnostics influencing the decision-making process. It can minimize the risk of misdiagnosis. Disclosure of the inner ear defect and its precise imaging provides detailed anatomical knowledge of each ear, enabling the selection of the appropriate cochlear implant electrode and the optimal surgical technique.</br>.
<b><br>引言:</b> 胚胎发育导致的先天性内耳畸形可在放射学扫描中看到。人们曾多次尝试根据解剖学和放射学结果对内耳缺陷进行描述和分类。</br><b><br><br>目的:</b></b></b><br><br><br>材料和方法:</b></b>对 22 例畸形内耳进行回顾性分析。使用多平面重建(MPR)选项和三维重建对 CT 扫描进行分析。确定了以下畸形:共同腔、耳蜗发育不良 II、III 和 IV 型、不完全分隔 II 和 III 型以及前庭迷宫畸形的各种组合。所有畸形都在图中进行了展示和强调,并配有相应的描述,以便于识别。正常内耳的图片也包括在内,以便进行比较。对每种畸形都进行了三维重建,为详细分析增加了临床价值。</br> <b><br>结论:</b> 在人工耳蜗植入咨询中正确分析 CT 扫描是选择合适人选和准备手术的必要且有益的工具。本研究提出的统一扫描评估方案简化了畸形的识别,降低了遗漏特定异常的风险。扫描的多平面评估提供了大部分必要的细节。三维重建技术除了影响决策过程的诊断外,还具有其他价值。它可以最大限度地降低误诊风险。揭示内耳缺陷及其精确成像可提供每只耳朵的详细解剖知识,从而选择合适的人工耳蜗电极和最佳手术技术。
{"title":"Computed tomography multi-planar and 3D image assessment protocol for detailed analysis of inner ear malformations in patients undergoing cochlear implantation counseling.","authors":"Agata Szleper, Magdalena Lachowska, Tomasz Wojciechowski, Kazimierz Niemczyk","doi":"10.5604/01.3001.0054.2567","DOIUrl":"https://doi.org/10.5604/01.3001.0054.2567","url":null,"abstract":"<p><p><b><br>Introduction:</b> Congenital inner ear malformations resulting from embryogenesis may be visualized in radiological scans. Many attempts have been made to describe and classify the defects of the inner ear based on anatomical and radiological findings.</br> <b><br>Aim:</b> The aim was to propose and discuss computed tomography multi-planar and 3D image assessment protocols for detailed analysis of inner ear malformations in patients undergoing cochlear implantation counseling.</br> <b><br>Material and methods:</b> A retrospective analysis of 22 malformed inner ears. CT scans were analyzed using the Multi-Planar Reconstruction (MPR) option and 3D reconstruction.</br> <b><br>Results:</b> The protocol of image interpretation was developed to allow reproducibility for evaluating each set of images. The following malformations were identified: common cavity, cochlear hypoplasia type II, III, and IV, incomplete partition type II and III, and various combinations of vestibule labyrinth malformations. All anomalies have been presented and highlighted in figures with appropriate descriptions for easier identification. Figures of normal inner ears were also included for comparison. 3D reconstructions for each malformation were presented, adding clinical value to the detailed analysis.</br> <b><br>Conclusions:</b> Properly analyzing CT scans in cochlear implantation counseling is a necessary and beneficial tool for appropriate candidate selection and preparation for surgery. As proposed in this study, the unified scans evaluation scheme simplifies the identification of malformations and reduces the risk of omitting particular anomalies. Multi-planar assessment of scans provides most of the necessary details. The 3D reconstruction technique is valuable in addition to diagnostics influencing the decision-making process. It can minimize the risk of misdiagnosis. Disclosure of the inner ear defect and its precise imaging provides detailed anatomical knowledge of each ear, enabling the selection of the appropriate cochlear implant electrode and the optimal surgical technique.</br>.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-09DOI: 10.5604/01.3001.0053.6158
Martina Kovalová, Nikol Gottfriedová, Eva Mrázková, Vladimír Janout, Jana Janoutová
<br><b>Introduction:</b> The early detection and diagnosis of dementia are of key importance in treatment, slowing disease progression, or suppressing symptoms. The possible role of changes in the sense of smell is considered with regard to potential markers for early detection of Alzheimer's disease (AD).</br> <br><b>Materials and methods:</b> A literature search was conducted using the electronic databases PubMed, Scopus, and Web of Science between May 30, 2022 and August 2, 2022. The term "dementia" was searched with keyword combinations related to olfaction.</br> <br><b>Results:</b> A total of 1,288 records were identified through the database search. Of these articles, 49 were ultimately included in the analysis. The results showed the potential role of changes in the sense of smell as potential biomarkers for early detection of AD. Multiple studies have shown that olfactory impairment may be observed in patients with AD, PD, MCI, or other types of dementia. Even though smell tests are able to detect olfactory loss caused by neurodegenerative diseases, they cannot reliably distinguish between certain diseases.</br> <br><b>Conclusions:</b> In individuals with cognitive impairment or neurodegenerative diseases, olfactory assessment has repeatedly been reported to be used for early diagnosis, but not for differential diagnosis.</br>.
</br><b>引言:</b>早期发现和诊断痴呆症对于治疗、减缓疾病进展或抑制症状至关重要。本研究考虑了嗅觉变化在早期检测阿尔茨海默病(AD)的潜在标志物方面可能发挥的作用</br><br><b>材料与方法:</b>在2022年5月30日至2022年8月2日期间,使用电子数据库PubMed、Scopus和Web of Science进行了文献检索。以 "痴呆症 "为关键词,搜索与嗅觉相关的关键词组合。其中 49 篇文章最终被纳入分析。研究结果表明,嗅觉的变化是早期检测注意力缺失症的潜在生物标志物。多项研究表明,AD、PD、MCI 或其他类型的痴呆症患者可能会出现嗅觉障碍。尽管嗅觉测试能够检测出神经退行性疾病导致的嗅觉缺失,但它们并不能可靠地区分某些疾病</br><br><b><b>结论:</b>对于患有认知障碍或神经退行性疾病的人,嗅觉评估多次被报道可用于早期诊断,但不能用于鉴别诊断</br></br>。
{"title":"Cognitive impairment, neurodegenerative disorders, and olfactory impairment: A literature review.","authors":"Martina Kovalová, Nikol Gottfriedová, Eva Mrázková, Vladimír Janout, Jana Janoutová","doi":"10.5604/01.3001.0053.6158","DOIUrl":"https://doi.org/10.5604/01.3001.0053.6158","url":null,"abstract":"<p><p><br><b>Introduction:</b> The early detection and diagnosis of dementia are of key importance in treatment, slowing disease progression, or suppressing symptoms. The possible role of changes in the sense of smell is considered with regard to potential markers for early detection of Alzheimer's disease (AD).</br> <br><b>Materials and methods:</b> A literature search was conducted using the electronic databases PubMed, Scopus, and Web of Science between May 30, 2022 and August 2, 2022. The term \"dementia\" was searched with keyword combinations related to olfaction.</br> <br><b>Results:</b> A total of 1,288 records were identified through the database search. Of these articles, 49 were ultimately included in the analysis. The results showed the potential role of changes in the sense of smell as potential biomarkers for early detection of AD. Multiple studies have shown that olfactory impairment may be observed in patients with AD, PD, MCI, or other types of dementia. Even though smell tests are able to detect olfactory loss caused by neurodegenerative diseases, they cannot reliably distinguish between certain diseases.</br> <br><b>Conclusions:</b> In individuals with cognitive impairment or neurodegenerative diseases, olfactory assessment has repeatedly been reported to be used for early diagnosis, but not for differential diagnosis.</br>.</p>","PeriodicalId":42608,"journal":{"name":"Polish Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}