Neurologic and Thrombotic Complications in the Setting of Chronic Nitrous Oxide Abuse.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL Case Reports in Medicine Pub Date : 2023-01-01 DOI:10.1155/2023/5058771
Erin Meier, Monica Malviya, Sukhdeep Kaur, Jacklynn Ibrahim, Andrew Corrigan, Andrew Moawad, Sathya Alekhya Bukkuri, Joshua Trebach, Mark K Su, Manju Pillai
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Abstract

Nitrous oxide is a commonly used inhaled anesthetic for medical procedures, as well as a drug of abuse throughout the world. Excessive nitrous oxide inhalation has been shown to cause a functional vitamin B12 deficiency and hyperhomocysteinemia, which can lead to peripheral neuropathy and hypercoagulability, respectively. While the development of neurologic toxicity from chronic nitrous oxide abuse (i.e., encephalopathy, myelopathy, and neuropathy) has been previously described, the thrombotic potential of chronic nitrous oxide abuse is less known. The authors report two cases of nitrous oxide abuse leading to both neurologic and thrombotic complications.

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慢性一氧化二氮滥用的神经系统和血栓并发症。
一氧化二氮是医疗过程中常用的吸入麻醉剂,也是世界各地滥用的药物。过量吸入一氧化二氮已被证明会导致功能性维生素B12缺乏症和高同型半胱氨酸血症,这两种疾病分别会导致周围神经病变和高凝血症。虽然慢性一氧化二氮滥用的神经毒性(即脑病、脊髓病和神经病)的发展已经被描述过,但慢性一氧化二氮滥用的血栓形成潜力却鲜为人知。作者报告了两例一氧化氮滥用导致神经系统和血栓并发症。
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来源期刊
Case Reports in Medicine
Case Reports in Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
1.70
自引率
0.00%
发文量
53
审稿时长
13 weeks
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