Injection of a Bone Substitute in the Treatment of Unicameral Bone Cysts.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-01-01 DOI:10.1155/2023/3270372
B Sivakumar, V V G An, A Dobbe, D Drynan, D Little
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引用次数: 1

Abstract

Background: Simple bone cysts are benign bony lesions. Treatment strategies are varied for this particular pathology. It remains controversial as to what the ideal treatment strategy is. Recently, bony substitute injections have emerged as a potential option for treatment. This paper aimed to describe our institution's experience in using bony substitute injections to treat unicameral bone cysts.

Methods: A retrospective review of consecutive patients over an 84-month period at a tertiary paediatric hospital was performed. Information regarding patients' presentation, diagnosis, and management was recorded and summarised.

Results: A total of 15 patients were included in our study, with a mean follow-up of 118 weeks. 86.7% of patients demonstrated clinical resolution (absence of pain at the latest follow-up) and 80% of patients demonstrated radiographic resolution. Only one patient sustained a subtrochanteric fracture post-index operation, whilst two others demonstrated redevelopment of cystic architecture on follow-up.

Conclusion: This study demonstrates that bone substitute injection is potentially a minimally invasive and seemingly successful technique in the treatment of unicameral bone cysts and other simple bone lesions. Further randomised and comparative studies are required to confirm and validate our findings.

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注射骨替代物治疗单侧骨囊肿。
背景:单纯性骨囊肿是一种良性的骨性病变。对于这种特殊的病理,治疗策略是多种多样的。理想的治疗策略是什么仍然存在争议。最近,骨替代注射已成为治疗的潜在选择。本文旨在介绍我院应用骨替代物注射治疗单院系骨囊肿的经验。方法:对一家三级儿科医院84个月的连续患者进行回顾性分析。记录和总结有关患者的表现、诊断和管理的信息。结果:本研究共纳入15例患者,平均随访118周。86.7%的患者表现出临床缓解(最新随访时无疼痛),80%的患者表现出影像学缓解。只有一名患者在指数手术后出现转子下骨折,而另外两名患者在随访中表现出囊性结构的再开发。结论:本研究表明骨替代物注射是治疗单侧骨囊肿和其他单纯性骨病变的一种潜在的微创且看似成功的技术。需要进一步的随机对照研究来证实和验证我们的发现。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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