Pub Date : 2025-01-22eCollection Date: 2025-01-01DOI: 10.1155/aort/8494043
Anitesh Bajaj, Rushmin Khazanchi, Rohan M Shah, Joshua P Weissman, Nishanth S Sadagopan, Arun K Gosain
Background: The present study analyzes the effects of preoperative serum albumin, hematocrit, and creatinine on postoperative outcomes in patients undergoing carpal tunnel decompression surgery. Methods: The American College of Surgeons National Quality Improvement Program (NSQIP) database was queried from 2011 to 2020. Albumin, hematocrit, and creatinine were collected for each patient, alongside covariates. Outcomes included 30-day medical complications, 30-day wound complications, return to the operating room, nonhome discharge, and extended postoperative length of stay. Bivariate t-tests and multivariate logistic regressions were conducted. For any outcome-laboratory value pairs with significance on regression, area under the receiver operating characteristic curves (AUC) were constructed. Results: A total of 1440 patients with albumin, 3138 patients with hematocrit, and 3159 patients with creatinine levels were identified. Increased serum albumin was associated with lower odds of medical complications (aOR: 0.479, p=0.035). An overall cohort cutoff of ≤ 3.5 g/dL (AUC: 0.79, p < 0.001) was predictive of medical complications. On multivariate logistic regression, increased hematocrit reduced the odds of medical complications (aOR: 0.889, p < 0.001). Predictive hematocrit cutoffs of ≤ 39.7% (AUC: 0.77, p < 0.001) and ≤ 36.6% (AUC: 0.74, p < 0.001) were identified for medical complications amongst male and female patients, respectively. Similarly, increased serum creatinine was associated with greater odds of medical complications (aOR: 1.684, p=0.006). Creatinine cutoffs of ≥ 1.2 mg/dL (AUC: 0.58, p=0.033) and ≥ 1.0 mg/dL (AUC: 0.59, p=0.039) were identified for medical complications amongst male and female patients, respectively. Conclusions: Multiple preoperative serum values were predictive of postoperative medical complications, and laboratory value thresholds were identified in this carpal tunnel decompression cohort to aid in risk stratification.
{"title":"Exploring the Impact of Preoperative Laboratory Values on Short-Term Outcomes in Complex Carpal Tunnel Decompression Surgery.","authors":"Anitesh Bajaj, Rushmin Khazanchi, Rohan M Shah, Joshua P Weissman, Nishanth S Sadagopan, Arun K Gosain","doi":"10.1155/aort/8494043","DOIUrl":"10.1155/aort/8494043","url":null,"abstract":"<p><p><b>Background:</b> The present study analyzes the effects of preoperative serum albumin, hematocrit, and creatinine on postoperative outcomes in patients undergoing carpal tunnel decompression surgery. <b>Methods:</b> The American College of Surgeons National Quality Improvement Program (NSQIP) database was queried from 2011 to 2020. Albumin, hematocrit, and creatinine were collected for each patient, alongside covariates. Outcomes included 30-day medical complications, 30-day wound complications, return to the operating room, nonhome discharge, and extended postoperative length of stay. Bivariate <i>t</i>-tests and multivariate logistic regressions were conducted. For any outcome-laboratory value pairs with significance on regression, area under the receiver operating characteristic curves (AUC) were constructed. <b>Results:</b> A total of 1440 patients with albumin, 3138 patients with hematocrit, and 3159 patients with creatinine levels were identified. Increased serum albumin was associated with lower odds of medical complications (aOR: 0.479, <i>p</i>=0.035). An overall cohort cutoff of ≤ 3.5 g/dL (AUC: 0.79, <i>p</i> < 0.001) was predictive of medical complications. On multivariate logistic regression, increased hematocrit reduced the odds of medical complications (aOR: 0.889, <i>p</i> < 0.001). Predictive hematocrit cutoffs of ≤ 39.7% (AUC: 0.77, <i>p</i> < 0.001) and ≤ 36.6% (AUC: 0.74, <i>p</i> < 0.001) were identified for medical complications amongst male and female patients, respectively. Similarly, increased serum creatinine was associated with greater odds of medical complications (aOR: 1.684, <i>p</i>=0.006). Creatinine cutoffs of ≥ 1.2 mg/dL (AUC: 0.58, <i>p</i>=0.033) and ≥ 1.0 mg/dL (AUC: 0.59, <i>p</i>=0.039) were identified for medical complications amongst male and female patients, respectively. <b>Conclusions:</b> Multiple preoperative serum values were predictive of postoperative medical complications, and laboratory value thresholds were identified in this carpal tunnel decompression cohort to aid in risk stratification.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2025 ","pages":"8494043"},"PeriodicalIF":1.2,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11779986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-20eCollection Date: 2025-01-01DOI: 10.1155/aort/2970626
Lorenzo Andreani, Edoardo Ipponi, Francesco Pecchia, Giorgio Balestrieri, Edoardo Tosi, Stefano Marchetti, Paolo Domenico Parchi
Background: Orthopedic trauma is a significant component of emergency department workloads worldwide. The relationship between weather conditions and injury rates is controversial in modern literature. Even less has been written to investigate bank holidays' influence on contusions, dislocations, fractures, and even polytrauma. Our study aimed to assess whether meteorological factors and national holidays could vary the workloads in the orthopedic ER of a European third-level trauma center. Materials and Methods: Our study consisted of a review of all the patients who underwent orthopedic evaluations in our institution's orthopedic emergency room between 2019 and 2023. Days were divided depending on weather (cloudy or sunny vs. rainy or stormy), day type (regular working days vs. national public holidays vs. Saturdays and Sundays), and presence or absence of COVID-19 restrictions. We also recorded the temperatures of each day. Cases were subdivided into three groups: cases without significant injuries (Group A), cases with isolated bone fractures, major tears or articular dislocations (Group B1), and polytrauma (Group B2). Results: Higher temperatures were associated with a significant increase in overall ER visits, isolated injuries, and polytrauma. Sunny or cloudy days had a significantly higher number of patients with all injury types compared to rainy or stormy days. Weekends saw a significant decrease in overall admissions and isolated injuries but a higher rate of polytrauma compared to weekdays. National holidays had a significantly lower number of admissions for all injury types compared to weekdays. Restrictions due to the pandemic significantly reduced overall ER visits. Conclusion: Temperatures, meteorological factors, and national holidays could vary the workloads in the orthopedic ER of a European third-level trauma center.
{"title":"Impact of Weather and Holidays on Orthopedic Emergency Room Crowding, Fractures, and Polytraumas in a Third-Level Referral Trauma Center in Europe.","authors":"Lorenzo Andreani, Edoardo Ipponi, Francesco Pecchia, Giorgio Balestrieri, Edoardo Tosi, Stefano Marchetti, Paolo Domenico Parchi","doi":"10.1155/aort/2970626","DOIUrl":"10.1155/aort/2970626","url":null,"abstract":"<p><p><b>Background:</b> Orthopedic trauma is a significant component of emergency department workloads worldwide. The relationship between weather conditions and injury rates is controversial in modern literature. Even less has been written to investigate bank holidays' influence on contusions, dislocations, fractures, and even polytrauma. Our study aimed to assess whether meteorological factors and national holidays could vary the workloads in the orthopedic ER of a European third-level trauma center. <b>Materials and Methods:</b> Our study consisted of a review of all the patients who underwent orthopedic evaluations in our institution's orthopedic emergency room between 2019 and 2023. Days were divided depending on weather (cloudy or sunny vs. rainy or stormy), day type (regular working days vs. national public holidays vs. Saturdays and Sundays), and presence or absence of COVID-19 restrictions. We also recorded the temperatures of each day. Cases were subdivided into three groups: cases without significant injuries (Group A), cases with isolated bone fractures, major tears or articular dislocations (Group B1), and polytrauma (Group B2). <b>Results:</b> Higher temperatures were associated with a significant increase in overall ER visits, isolated injuries, and polytrauma. Sunny or cloudy days had a significantly higher number of patients with all injury types compared to rainy or stormy days. Weekends saw a significant decrease in overall admissions and isolated injuries but a higher rate of polytrauma compared to weekdays. National holidays had a significantly lower number of admissions for all injury types compared to weekdays. Restrictions due to the pandemic significantly reduced overall ER visits. <b>Conclusion:</b> Temperatures, meteorological factors, and national holidays could vary the workloads in the orthopedic ER of a European third-level trauma center.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2025 ","pages":"2970626"},"PeriodicalIF":1.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11772064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-06eCollection Date: 2025-01-01DOI: 10.1155/aort/5534704
Jonathan D Schwartzman, M Kareem Shaath, Matthew S Kerr, Cody C Green, George J Haidukewych
<p><p><b>Background:</b> Advances in artificial intelligence (AI), machine learning, and publicly accessible language model tools such as ChatGPT-3.5 continue to shape the landscape of modern medicine and patient education. ChatGPT's open access (OA), instant, human-sounding interface capable of carrying discussion on myriad topics makes it a potentially useful resource for patients seeking medical advice. As it pertains to orthopedic surgery, ChatGPT may become a source to answer common preoperative questions regarding total knee arthroplasty (TKA) and total hip arthroplasty (THA). Since ChatGPT can utilize the peer-reviewed literature to source its responses, this study seeks to characterize the validity of its responses to common TKA and THA questions and characterize the peer-reviewed literature that it uses to formulate its responses. <b>Methods:</b> Preoperative TKA and THA questions were formulated by fellowship-trained adult reconstruction surgeons based on common questions posed by patients in the clinical setting. Questions were inputted into ChatGPT with the initial request of using solely the peer-reviewed literature to generate its responses. The validity of each response was rated on a Likert scale by the fellowship-trained surgeons, and the sources utilized were characterized in terms of accuracy of comparison to existing publications, publication date, study design, level of evidence, journal of publication, journal impact factor based on the clarivate analytics factor tool, journal OA status, and whether the journal is based in the United States. <b>Results:</b> A total of 109 sources were cited by ChatGPT in its answers to 17 questions regarding TKA procedures and 16 THA procedures. Thirty-nine sources (36%) were deemed accurate or able to be directly traced to an existing publication. Of these, seven (18%) were identified as duplicates, yielding a total of 32 unique sources that were identified as accurate and further characterized. The most common characteristics of these sources included dates of publication between 2011 and 2015 (10), publication in The Journal of Bone and Joint Surgery (13), journal impact factors between 5.1 and 10.0 (17), internationally based journals (17), and journals that are not OA (28). The most common study designs were retrospective cohort studies and case series (seven each). The level of evidence was broadly distributed between Levels I, III, and IV (seven each). The averages for the Likert scales for medical accuracy and completeness were 4.4/6 and 1.92/3, respectively. <b>Conclusions:</b> Investigation into ChatGPT's response quality and use of peer-reviewed sources when prompted with archetypal pre-TKA and pre-THA questions found ChatGPT to provide mostly reliable responses based on fellowship-trained orthopedic surgeon review of 4.4/6 for accuracy and 1.92/3 for completeness despite a 64.22% rate of citing inaccurate references. This study suggests that until ChatGPT is proven to be a reliab
背景:人工智能(AI)、机器学习和可公开访问的语言模型工具(如ChatGPT-3.5)的进步继续塑造现代医学和患者教育的格局。ChatGPT的开放访问(OA)、即时、人性化的界面能够就无数主题进行讨论,这使其成为寻求医疗建议的患者的潜在有用资源。由于它与骨科手术有关,ChatGPT可能成为解答全膝关节置换术(TKA)和全髋关节置换术(THA)术前常见问题的来源。由于ChatGPT可以利用同行评议的文献来获取其回答,因此本研究试图表征其对常见TKA和THA问题的回答的有效性,并表征其用于制定其回答的同行评议文献。方法:术前TKA和THA的问题是由研究员培训的成人重建外科医生根据患者在临床环境中提出的常见问题制定的。问题被输入到ChatGPT中,最初的要求是仅使用同行评审的文献来生成答案。每个回答的有效性由接受过奖学金培训的外科医生用李克特量表进行评分,并根据与现有出版物比较的准确性、出版日期、研究设计、证据水平、出版期刊、基于clarivate分析因子工具的期刊影响因子、期刊OA状态以及该期刊是否在美国进行特征描述。结果:ChatGPT在回答TKA程序的17个问题和THA程序的16个问题时共引用了109个来源。39个来源(36%)被认为是准确的或能够直接追溯到现有出版物。其中,7个(18%)被鉴定为重复,总共产生32个被鉴定为准确并进一步表征的独特来源。这些来源最常见的特征包括发表日期在2011年至2015年之间(10),发表于The Journal of Bone and Joint Surgery(13),期刊影响因子在5.1至10.0之间(17),国际期刊(17)和非OA期刊(28)。最常见的研究设计是回顾性队列研究和病例系列研究(各7例)。证据水平大致分布在I级、III级和IV级之间(各7个)。Likert量表的医疗准确性和完整性的平均值分别为4.4/6和1.92/3。结论:对ChatGPT的回答质量和使用同行评议的资料进行的调查发现,尽管引用不准确参考文献的比例为64.22%,但ChatGPT提供的回答大部分是可靠的,其准确性为4.4/6,完整性为1.92/3。本研究提示,在ChatGPT被证明是有效信息和参考的可靠来源之前,患者在将tka前和THA问题导向该媒介时必须非常谨慎。
{"title":"ChatGPT is an Unreliable Source of Peer-Reviewed Information for Common Total Knee and Hip Arthroplasty Patient Questions.","authors":"Jonathan D Schwartzman, M Kareem Shaath, Matthew S Kerr, Cody C Green, George J Haidukewych","doi":"10.1155/aort/5534704","DOIUrl":"10.1155/aort/5534704","url":null,"abstract":"<p><p><b>Background:</b> Advances in artificial intelligence (AI), machine learning, and publicly accessible language model tools such as ChatGPT-3.5 continue to shape the landscape of modern medicine and patient education. ChatGPT's open access (OA), instant, human-sounding interface capable of carrying discussion on myriad topics makes it a potentially useful resource for patients seeking medical advice. As it pertains to orthopedic surgery, ChatGPT may become a source to answer common preoperative questions regarding total knee arthroplasty (TKA) and total hip arthroplasty (THA). Since ChatGPT can utilize the peer-reviewed literature to source its responses, this study seeks to characterize the validity of its responses to common TKA and THA questions and characterize the peer-reviewed literature that it uses to formulate its responses. <b>Methods:</b> Preoperative TKA and THA questions were formulated by fellowship-trained adult reconstruction surgeons based on common questions posed by patients in the clinical setting. Questions were inputted into ChatGPT with the initial request of using solely the peer-reviewed literature to generate its responses. The validity of each response was rated on a Likert scale by the fellowship-trained surgeons, and the sources utilized were characterized in terms of accuracy of comparison to existing publications, publication date, study design, level of evidence, journal of publication, journal impact factor based on the clarivate analytics factor tool, journal OA status, and whether the journal is based in the United States. <b>Results:</b> A total of 109 sources were cited by ChatGPT in its answers to 17 questions regarding TKA procedures and 16 THA procedures. Thirty-nine sources (36%) were deemed accurate or able to be directly traced to an existing publication. Of these, seven (18%) were identified as duplicates, yielding a total of 32 unique sources that were identified as accurate and further characterized. The most common characteristics of these sources included dates of publication between 2011 and 2015 (10), publication in The Journal of Bone and Joint Surgery (13), journal impact factors between 5.1 and 10.0 (17), internationally based journals (17), and journals that are not OA (28). The most common study designs were retrospective cohort studies and case series (seven each). The level of evidence was broadly distributed between Levels I, III, and IV (seven each). The averages for the Likert scales for medical accuracy and completeness were 4.4/6 and 1.92/3, respectively. <b>Conclusions:</b> Investigation into ChatGPT's response quality and use of peer-reviewed sources when prompted with archetypal pre-TKA and pre-THA questions found ChatGPT to provide mostly reliable responses based on fellowship-trained orthopedic surgeon review of 4.4/6 for accuracy and 1.92/3 for completeness despite a 64.22% rate of citing inaccurate references. This study suggests that until ChatGPT is proven to be a reliab","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2025 ","pages":"5534704"},"PeriodicalIF":1.2,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-24eCollection Date: 2024-01-01DOI: 10.1155/aort/5663025
Mohamed I Abulsoud, Mohammed Elmarghany, Ahmed R Zakaria, Ehab A Alshal, Mohamed Moawad, Ehab A Elzahed, Mohamed F Elhalawany, Bahaa A Kornah
Objective: The purpose of this study is to investigate the outcomes of the use of a 2.7 mm semitubular hook plate for internal fixation of unstable metaphyseal ulnar fractures. Methods: Between January 2015 and July 2019, 30 consecutive patients with a recent unstable distal ulnar fracture were included in this prospective case series. All patients were subjected to follow-up with the time of union, range of motion, pain using a Visual Analog Scale (VAS), and radiological and functional outcome using the quick Disabilities of the Arm, Shoulder, and Hand (DASH) score and Mayo wrist score after 12 months. Results: The mean age of the patients was 45.3 ± 10 years. There were 18 males (60%) and 12 females (40%), and there were 16 patients associated with distal radius fractures (53.33%). According to the AO classification of distal ulnar fractures, 3 fractures were type A2.1 (10%), 9 were type A2.2 (30%), 8 fractures were type A2.3 (26.67%), and 10 fractures were type A3 (33.33%). All fractures have been united with a mean duration of 9 ± 1.4 weeks, the mean supination was 81.4° ± 3.5°, the mean pronation was 81.3° ± 4.5°, the mean flexion was = 71.7° ± 3.6°, and the mean extension was = 81.7° ± 3.4°. The mean VAS was 1.1 ± 1 points, the mean DASH score was 9.3 ± 5.6 points, and the mean Mayo wrist score was 88.5 ± 7.2 points; 17 patients were excellent (56.67%) and 10 patients were good (33.33%) while 3 patients had satisfactory outcome (10%). Conclusion: Using the 2.7 mm semitubular hook plate is a successful choice for internal fixation of unstable distal ulnar fractures isolated or associated with distal radius fractures with a favorable union time, functional outcome, and range of motion with minimal complications.
{"title":"Internal Fixation for Unstable Distal Ulnar Fractures by 2.7 mm Semitubular Hook Plate.","authors":"Mohamed I Abulsoud, Mohammed Elmarghany, Ahmed R Zakaria, Ehab A Alshal, Mohamed Moawad, Ehab A Elzahed, Mohamed F Elhalawany, Bahaa A Kornah","doi":"10.1155/aort/5663025","DOIUrl":"10.1155/aort/5663025","url":null,"abstract":"<p><p><b>Objective:</b> The purpose of this study is to investigate the outcomes of the use of a 2.7 mm semitubular hook plate for internal fixation of unstable metaphyseal ulnar fractures. <b>Methods:</b> Between January 2015 and July 2019, 30 consecutive patients with a recent unstable distal ulnar fracture were included in this prospective case series. All patients were subjected to follow-up with the time of union, range of motion, pain using a Visual Analog Scale (VAS), and radiological and functional outcome using the quick Disabilities of the Arm, Shoulder, and Hand (DASH) score and Mayo wrist score after 12 months. <b>Results:</b> The mean age of the patients was 45.3 ± 10 years. There were 18 males (60%) and 12 females (40%), and there were 16 patients associated with distal radius fractures (53.33%). According to the AO classification of distal ulnar fractures, 3 fractures were type A2.1 (10%), 9 were type A2.2 (30%), 8 fractures were type A2.3 (26.67%), and 10 fractures were type A3 (33.33%). All fractures have been united with a mean duration of 9 ± 1.4 weeks, the mean supination was 81.4° ± 3.5°, the mean pronation was 81.3° ± 4.5°, the mean flexion was = 71.7° ± 3.6°, and the mean extension was = 81.7° ± 3.4°. The mean VAS was 1.1 ± 1 points, the mean DASH score was 9.3 ± 5.6 points, and the mean Mayo wrist score was 88.5 ± 7.2 points; 17 patients were excellent (56.67%) and 10 patients were good (33.33%) while 3 patients had satisfactory outcome (10%). <b>Conclusion:</b> Using the 2.7 mm semitubular hook plate is a successful choice for internal fixation of unstable distal ulnar fractures isolated or associated with distal radius fractures with a favorable union time, functional outcome, and range of motion with minimal complications.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"5663025"},"PeriodicalIF":1.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11688142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-19eCollection Date: 2024-01-01DOI: 10.1155/2024/6551525
Silviu Valentin Vlad, Timea Claudia Ghitea, Felicia Manole, Alexandru-Stefan Nutiu, Alex Octavian Lupsa, Nicu Adrian Ghiurau, Florin Nicolae Blaga
Platelet-rich plasma (PRP) is gaining popularity across various medical fields, including orthopedics, for its potential in tissue regeneration and wound healing. As intra-articular treatments evolve, PRP has emerged as a promising option for managing knee osteoarthritis, meniscus, and ligament injuries. This review aims to provide an update on the current applications of PRP in treating knee osteoarthritis and its clinical implications in orthopedic and sports medicine. We reviewed 180 eligible studies, and our findings suggest that PRP injections significantly improve knee joint function compared to alternative treatments. The use of PRP across various medical fields has been growing in popularity recently. PRP is a biological product derived from the plasma portion of a patient's own blood, containing a higher concentration of platelets than normal. Its potential for tissue regeneration and wound healing has drawn significant attention from orthopedic surgeons, especially as intra-articular treatment options continue to evolve. The benefits of PRP in treating various osteoarticular conditions have sparked considerable interest within the orthopedic community, particularly for managing knee osteoarthritis, meniscus tears, and ligament injuries. This review aims to provide an updated overview of the current applications of PRP in the treatment of knee osteoarthritis and to offer clinical insights into its use in orthopedic and sports medicine practices. We reviewed 180 relevant titles and abstracts that met the inclusion criteria. Compared to other treatment options, PRP injections significantly enhance knee joint function.
{"title":"Addressing Knee Osteoarthritis Pathology Through Platelet-Rich Plasma Treatment: A Comprehensive Review.","authors":"Silviu Valentin Vlad, Timea Claudia Ghitea, Felicia Manole, Alexandru-Stefan Nutiu, Alex Octavian Lupsa, Nicu Adrian Ghiurau, Florin Nicolae Blaga","doi":"10.1155/2024/6551525","DOIUrl":"10.1155/2024/6551525","url":null,"abstract":"<p><p>Platelet-rich plasma (PRP) is gaining popularity across various medical fields, including orthopedics, for its potential in tissue regeneration and wound healing. As intra-articular treatments evolve, PRP has emerged as a promising option for managing knee osteoarthritis, meniscus, and ligament injuries. This review aims to provide an update on the current applications of PRP in treating knee osteoarthritis and its clinical implications in orthopedic and sports medicine. We reviewed 180 eligible studies, and our findings suggest that PRP injections significantly improve knee joint function compared to alternative treatments. The use of PRP across various medical fields has been growing in popularity recently. PRP is a biological product derived from the plasma portion of a patient's own blood, containing a higher concentration of platelets than normal. Its potential for tissue regeneration and wound healing has drawn significant attention from orthopedic surgeons, especially as intra-articular treatment options continue to evolve. The benefits of PRP in treating various osteoarticular conditions have sparked considerable interest within the orthopedic community, particularly for managing knee osteoarthritis, meniscus tears, and ligament injuries. This review aims to provide an updated overview of the current applications of PRP in the treatment of knee osteoarthritis and to offer clinical insights into its use in orthopedic and sports medicine practices. We reviewed 180 relevant titles and abstracts that met the inclusion criteria. Compared to other treatment options, PRP injections significantly enhance knee joint function.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"6551525"},"PeriodicalIF":1.2,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11599444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-26eCollection Date: 2024-01-01DOI: 10.1155/2024/2371242
Panagiotis Karampinas, John Vlamis, Athanasios Galanis, Michail Vavourakis, Evangelos Sakellariou, Iordanis Varsamos, Ioannis Spyrou, Spiros Pneumaticos
Background: The development of less invasive all-inside techniques regarding anterior cruciate ligament (ACL) reconstruction surgery has been associated with various advantages, including fewer complications and reduced postoperative pain. Silva et al. described a quadruple semitendinosus graft construct and suspensory button fixation for ACL reconstruction as an alternative technique. At the end of this technique, the tibial tunnel is filled with a bone autograft plug. This paper aims to examine the incorporation of the autograft and thus evaluate whether the "Silva technique" provides the same benefits as all-inside techniques. Methods: A prospective study assessed 31 patients undergoing ACL reconstruction surgery using the "Silva technique." The cases involved in the study were skeletally mature patients with no previous history of ACL surgery or multiligamentous instability. All patients followed the same rehabilitation program and were examined at three standardized follow-up visits: 4 months, 8 months, and 1 year postoperatively. Tegner-Lysholm knee score (TLKS), visual analog score (VAS) for pain, and the IKDC subjective knee score were completed at every visit. A knee MRI scan was performed at every scheduled visit to assess bone graft incorporation and remodeling. Results: TLKS scores revealed a considerable improvement compared to preoperative figures, from 57.2 points preoperatively to an average of 99.4 at the 12-month follow-up (p < 0.0001). VAS scores were substantially ameliorated after the operation and until the second follow-up visit, from 5 before surgery to zero 8 months after the operation, with no noteworthy alterations afterward (p < 0.0001). IKDC subjective knee score outcomes were found to have increased at the last follow-up, from 59.3 prior to surgery to 99.8 12 months postoperatively (p < 0.0001). Regarding the MRI features of the bone autograft, the tibial tunnel was entirely filled by bone formation at the last MRI scan, suggesting complete integration of the autograft in all patients. Conclusions: Bone autograft employed to seal the tibial tunnel was completely incorporated in all cases 1 year postoperatively. The "Silva technique" appears to feature all the avails of all-inside techniques, whilst it seems to be simpler and easier than them after the surgeon is familiarized with its particular aspects. It is a robust option in orthopedic surgeons' arsenal. However, further large-scale pertinent research is requisite to confirm the findings of this study.
背景:前交叉韧带(ACL)重建手术采用创伤较小的全内侧技术,具有减少并发症和减轻术后疼痛等多种优势。Silva 等人描述了一种用于前交叉韧带重建的四重半腱肌移植物构建和悬吊扣固定替代技术。在该技术的最后,胫骨隧道被自体骨移植塞填满。本文旨在研究自体移植物的植入情况,从而评估 "席尔瓦技术 "是否与全内侧技术具有相同的优势。研究方法一项前瞻性研究评估了31名使用 "席尔瓦技术 "进行前交叉韧带重建手术的患者。参与研究的病例均为骨骼发育成熟的患者,既往无前交叉韧带手术史或多韧带不稳定史。所有患者都接受了相同的康复计划,并在三次标准化随访中接受了检查:术后 4 个月、8 个月和 1 年。每次随访都要完成 Tegner-Lysholm 膝关节评分(TLKS)、疼痛视觉模拟评分(VAS)和 IKDC 膝关节主观评分。每次预约就诊时都进行膝关节核磁共振扫描,以评估植骨融合和重塑情况。结果TLKS 评分与术前相比有了显著改善,从术前的 57.2 分提高到 12 个月随访时的平均 99.4 分(P P P P 结论):在所有病例中,术后 1 年用于封闭胫骨隧道的骨自体移植物都完全融入了胫骨隧道。Silva技术 "似乎具有全内技术的所有优点,但在外科医生熟悉其特殊方面后,它似乎比全内技术更简单、更容易。在骨科医生的武器库中,这是一个强有力的选择。不过,要证实这项研究的结果,还需要进一步开展大规模的相关研究。
{"title":"Is Anterior Cruciate Ligament Reconstruction \"Silva Technique\" Equal to All-Inside Techniques? A Prospective Single-Center Study: An Alternative ACL All-Inside Reconstruction Technique Using a Tibial Tunnel and Bone Graft.","authors":"Panagiotis Karampinas, John Vlamis, Athanasios Galanis, Michail Vavourakis, Evangelos Sakellariou, Iordanis Varsamos, Ioannis Spyrou, Spiros Pneumaticos","doi":"10.1155/2024/2371242","DOIUrl":"10.1155/2024/2371242","url":null,"abstract":"<p><p><b>Background:</b> The development of less invasive all-inside techniques regarding anterior cruciate ligament (ACL) reconstruction surgery has been associated with various advantages, including fewer complications and reduced postoperative pain. Silva et al. described a quadruple semitendinosus graft construct and suspensory button fixation for ACL reconstruction as an alternative technique. At the end of this technique, the tibial tunnel is filled with a bone autograft plug. This paper aims to examine the incorporation of the autograft and thus evaluate whether the \"Silva technique\" provides the same benefits as all-inside techniques. <b>Methods:</b> A prospective study assessed 31 patients undergoing ACL reconstruction surgery using the \"Silva technique.\" The cases involved in the study were skeletally mature patients with no previous history of ACL surgery or multiligamentous instability. All patients followed the same rehabilitation program and were examined at three standardized follow-up visits: 4 months, 8 months, and 1 year postoperatively. Tegner-Lysholm knee score (TLKS), visual analog score (VAS) for pain, and the IKDC subjective knee score were completed at every visit. A knee MRI scan was performed at every scheduled visit to assess bone graft incorporation and remodeling. <b>Results:</b> TLKS scores revealed a considerable improvement compared to preoperative figures, from 57.2 points preoperatively to an average of 99.4 at the 12-month follow-up (<i>p</i> < 0.0001). VAS scores were substantially ameliorated after the operation and until the second follow-up visit, from 5 before surgery to zero 8 months after the operation, with no noteworthy alterations afterward (<i>p</i> < 0.0001). IKDC subjective knee score outcomes were found to have increased at the last follow-up, from 59.3 prior to surgery to 99.8 12 months postoperatively (<i>p</i> < 0.0001). Regarding the MRI features of the bone autograft, the tibial tunnel was entirely filled by bone formation at the last MRI scan, suggesting complete integration of the autograft in all patients. <b>Conclusions:</b> Bone autograft employed to seal the tibial tunnel was completely incorporated in all cases 1 year postoperatively. The \"Silva technique\" appears to feature all the avails of all-inside techniques, whilst it seems to be simpler and easier than them after the surgeon is familiarized with its particular aspects. It is a robust option in orthopedic surgeons' arsenal. However, further large-scale pertinent research is requisite to confirm the findings of this study.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"2371242"},"PeriodicalIF":1.2,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-25eCollection Date: 2024-01-01DOI: 10.1155/2024/6158822
Sebastian Winther, Naima Elsayed, Karen Dyreborg, Elinborg Mortensen, Michael M Petersen, Jens Stürup, Nikolaj S Winther
Background and Purpose: Revision total hip arthroplasty (rTHA) is a challenging procedure especially in the presence of severe bone loss where implant fixation is compromised. The aim of this study was to evaluate implant survival, clinical outcome, and midterm results in a group of complex patients after femoral revision using an uncemented modular implant design. Patients and Methods: We performed a retrospective study including 100 patients (101 hips) treated with revision THA using an uncemented modular implant design. We identified 51 hips as Paprosky types I-II and 50 hips as Paprosky III-IV bone defects. We reviewed operative reports and radiographs. Patients underwent a clinical examination to assess the Harris Hip Score (HHS) and completed patient-reported outcome measures (PROM), including the Oxford Hip Score (OHS) and the EQ-5D Visual Analog Scale (VAS). Minimum follow-up was 2 years (average, 5.8 years; range, 2.0-9.4 years). Results: Among the cases, 46 hips were revised for infection in a 2-stage procedure and 44 hips for aseptic loosening. 11 hips had periprosthetic fractures of Vancouver type B2 or B3. A total of 5 hips required revision with removal of the femoral implant and 11 patients experienced complications resulting in fracture (n = 1), dislocation (n = 10), and soft tissue revision (n = 1). The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%). All hips had radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Additionally, 80% showed radiographic evidence of restoration of proximal femoral bone. Mean HHS was 78. Conclusion: In complex cases of revision THA, using a modular revision femoral system yielded promising results. The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%), with all hips demonstrating radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Notably 80% showed radiographic evidence of restoration of proximal femoral bone.
{"title":"Implant Survival of an Uncemented Modular Femoral Implant in Patients With Severe Femoral Bone Loss and 2-Stage Hip Revision.","authors":"Sebastian Winther, Naima Elsayed, Karen Dyreborg, Elinborg Mortensen, Michael M Petersen, Jens Stürup, Nikolaj S Winther","doi":"10.1155/2024/6158822","DOIUrl":"10.1155/2024/6158822","url":null,"abstract":"<p><p><b>Background and Purpose:</b> Revision total hip arthroplasty (rTHA) is a challenging procedure especially in the presence of severe bone loss where implant fixation is compromised. The aim of this study was to evaluate implant survival, clinical outcome, and midterm results in a group of complex patients after femoral revision using an uncemented modular implant design. <b>Patients and Methods:</b> We performed a retrospective study including 100 patients (101 hips) treated with revision THA using an uncemented modular implant design. We identified 51 hips as Paprosky types I-II and 50 hips as Paprosky III-IV bone defects. We reviewed operative reports and radiographs. Patients underwent a clinical examination to assess the Harris Hip Score (HHS) and completed patient-reported outcome measures (PROM), including the Oxford Hip Score (OHS) and the EQ-5D Visual Analog Scale (VAS). Minimum follow-up was 2 years (average, 5.8 years; range, 2.0-9.4 years). <b>Results:</b> Among the cases, 46 hips were revised for infection in a 2-stage procedure and 44 hips for aseptic loosening. 11 hips had periprosthetic fractures of Vancouver type B2 or B3. A total of 5 hips required revision with removal of the femoral implant and 11 patients experienced complications resulting in fracture (<i>n</i> = 1), dislocation (<i>n</i> = 10), and soft tissue revision (<i>n</i> = 1). The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%). All hips had radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Additionally, 80% showed radiographic evidence of restoration of proximal femoral bone. Mean HHS was 78. <b>Conclusion:</b> In complex cases of revision THA, using a modular revision femoral system yielded promising results. The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%), with all hips demonstrating radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Notably 80% showed radiographic evidence of restoration of proximal femoral bone.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"6158822"},"PeriodicalIF":1.2,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142566677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-12eCollection Date: 2024-01-01DOI: 10.1155/2024/7933520
Alexandra Ciuciu, Christopher Mulholland, Michael A Bozzi, Chris C Frymoyer, Leonardo Cavinatto, David Yaron, Marc I Harwood, Jeremy D Close, Christopher J Mehallo, Ryan E Tomlinson
Previous studies have shown that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased stress fracture risk. This phenomenon has been studied predominantly in high-activity individuals, so data regarding the general population are limited despite the substantial economic and resource burden of stress fracture injuries within the general US population. Furthermore, our preclinical studies demonstrate that regular use of NSAIDs also diminishes the intrinsic ability of bone to resist fracture. To determine the association of regular NSAID use with stress fractures in the general population, we surveyed subjects presenting with either stress fracture or uncomplicated ankle sprain to assess their use of NSAIDs over the three months before their injury. We hypothesized that subjects with stress fractures would have increased regular NSAID usage as compared to controls. Subjects diagnosed with a stress fracture (n = 56) and subjects with uncomplicated ankle sprains (n = 51; control) were surveyed about their NSAID use at the time of their diagnosis and in the previous three months using a questionnaire based on the National Health and Nutrition Examination Survey (NHANES). Subjects were surveyed in person on the day of their injury diagnosis or by phone within 30 days of their diagnosis. Fisher's exact test was used to determine significant differences in NSAID usage between stress fracture and control subjects. Subjects diagnosed with stress fractures had a statistically significant increase in both current use (p=0.03) and regular use (p=0.04) of ibuprofen/naproxen/celecoxib as compared to control subjects. There were no significant differences in the use of aspirin, acetaminophen, or prescription medications containing acetaminophen between groups. Consistent with previous clinical reports, we observed a strong correlation between regular ibuprofen/naproxen/celecoxib use and stress fracture incidence in the general population. These results indicate that patients at high risk of stress fracture should avoid regular use of ibuprofen, naproxen, or celecoxib.
{"title":"Regular Nonsteroidal Anti-Inflammatory Drug Use Increases Stress Fracture Risk in the General Population: A Retrospective Case-Control Study.","authors":"Alexandra Ciuciu, Christopher Mulholland, Michael A Bozzi, Chris C Frymoyer, Leonardo Cavinatto, David Yaron, Marc I Harwood, Jeremy D Close, Christopher J Mehallo, Ryan E Tomlinson","doi":"10.1155/2024/7933520","DOIUrl":"10.1155/2024/7933520","url":null,"abstract":"<p><p>Previous studies have shown that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased stress fracture risk. This phenomenon has been studied predominantly in high-activity individuals, so data regarding the general population are limited despite the substantial economic and resource burden of stress fracture injuries within the general US population. Furthermore, our preclinical studies demonstrate that regular use of NSAIDs also diminishes the intrinsic ability of bone to resist fracture. To determine the association of regular NSAID use with stress fractures in the general population, we surveyed subjects presenting with either stress fracture or uncomplicated ankle sprain to assess their use of NSAIDs over the three months before their injury. We hypothesized that subjects with stress fractures would have increased regular NSAID usage as compared to controls. Subjects diagnosed with a stress fracture (<i>n</i> = 56) and subjects with uncomplicated ankle sprains (<i>n</i> = 51; control) were surveyed about their NSAID use at the time of their diagnosis and in the previous three months using a questionnaire based on the National Health and Nutrition Examination Survey (NHANES). Subjects were surveyed in person on the day of their injury diagnosis or by phone within 30 days of their diagnosis. Fisher's exact test was used to determine significant differences in NSAID usage between stress fracture and control subjects. Subjects diagnosed with stress fractures had a statistically significant increase in both current use (<i>p</i>=0.03) and regular use (<i>p</i>=0.04) of ibuprofen/naproxen/celecoxib as compared to control subjects. There were no significant differences in the use of aspirin, acetaminophen, or prescription medications containing acetaminophen between groups. Consistent with previous clinical reports, we observed a strong correlation between regular ibuprofen/naproxen/celecoxib use and stress fracture incidence in the general population. These results indicate that patients at high risk of stress fracture should avoid regular use of ibuprofen, naproxen, or celecoxib.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"7933520"},"PeriodicalIF":1.2,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11490349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this review paper, we present the common etiology, presentation, diagnosis, and management of the following three common bunion formations: dorsal bunion, tailor's bunion, and hallux valgus (HV). Bunions are common pathologies that present to a variety of clinics, so it is important for providers to have a base understanding of these in order to provide the best care to patients. Many of these bunion formations have a variety of causes which allow providers to manage them before surgical intervention is required. The aim of this review paper is to bring attention and expanded insight on these common bunion presentations in order to minimize morbidity early on. The information provided in this review will allow both primary care and subspecialty physicians with the knowledge to accurately diagnose and optimally manage these bony deformities of the lower extremity.
{"title":"From Etiology to Intervention: A Holistic Review of Bunion Pathophysiology and Care.","authors":"Danielle Barnes, Paige Matijasich, Aidan Maxwell, David Yatsonsky, Audrey Ballard, Nabil Ebraheim, Osama Elattar","doi":"10.1155/2024/9910410","DOIUrl":"10.1155/2024/9910410","url":null,"abstract":"<p><p>In this review paper, we present the common etiology, presentation, diagnosis, and management of the following three common bunion formations: dorsal bunion, tailor's bunion, and hallux valgus (HV). Bunions are common pathologies that present to a variety of clinics, so it is important for providers to have a base understanding of these in order to provide the best care to patients. Many of these bunion formations have a variety of causes which allow providers to manage them before surgical intervention is required. The aim of this review paper is to bring attention and expanded insight on these common bunion presentations in order to minimize morbidity early on. The information provided in this review will allow both primary care and subspecialty physicians with the knowledge to accurately diagnose and optimally manage these bony deformities of the lower extremity.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"9910410"},"PeriodicalIF":1.2,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11489004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-30eCollection Date: 2024-01-01DOI: 10.1155/2024/7708192
Rohun Gupta, Isabel Herzog, Lauren Phung, Jacquelyn Roth, Joseph Weisberger, Margaret Luthringer, Edward S Lee, Ashley Ignatiuk
Introduction: Brachial plexus injuries (BPI) from gunshot injuries are uncommon but usually severe and can cause chronic pain, loss of function, and permanent nerve damage. Multiple surgical techniques including neurolysis, end-to-end suture repair, and graft repair have been described for the treatment of these injuries. However, surgical indication, timing, and technique for these injuries remain controversial. This systematic review aims to investigate the treatment modalities for patients with BPI due to gunshot-related injuries.
Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) methodology was employed for this review. PubMed, Cochrane Reviews, Embase, and CINAHL databases were included. The following keywords constituted our search criteria: gun-shot-wounds, brachial plexus, traum∗, and management.
Results: A total of 90 studies were imported for screening, from which 9 papers met our final inclusion/exclusion criteria. The most common studies utilized in this review were retrospective chart reviews followed by case series. In total, there were 628 patients that suffered from gunshot wounds to the brachial plexus. Most patients underwent some form of delayed nerve repair consisting of neurolysis, end-to-end epineural repair, or graft repair with a sural or antebrachial cutaneous nerve graft. Several patients suffered from complications, with neuroma being the most common long-term complication that required reoperation.
Conclusion: The optimal timing for surgeries involving BPIs should be determined after examining the level of nerve damage, associated injuries, operative risks, and electrophysiological workup for indications of spontaneous regeneration. Early surgical interventions were indicated for patients presenting with associated vascular or thoracic injuries, compressive masses, and nerve transection by sharp instruments in most selected papers.
{"title":"Treatment of Brachial Plexus Injuries following Gunshot Injuries: A Systematic Review.","authors":"Rohun Gupta, Isabel Herzog, Lauren Phung, Jacquelyn Roth, Joseph Weisberger, Margaret Luthringer, Edward S Lee, Ashley Ignatiuk","doi":"10.1155/2024/7708192","DOIUrl":"10.1155/2024/7708192","url":null,"abstract":"<p><strong>Introduction: </strong>Brachial plexus injuries (BPI) from gunshot injuries are uncommon but usually severe and can cause chronic pain, loss of function, and permanent nerve damage. Multiple surgical techniques including neurolysis, end-to-end suture repair, and graft repair have been described for the treatment of these injuries. However, surgical indication, timing, and technique for these injuries remain controversial. This systematic review aims to investigate the treatment modalities for patients with BPI due to gunshot-related injuries.</p><p><strong>Methods: </strong>The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) methodology was employed for this review. PubMed, Cochrane Reviews, Embase, and CINAHL databases were included. The following keywords constituted our search criteria: gun-shot-wounds, brachial plexus, traum<sup>∗</sup>, and management.</p><p><strong>Results: </strong>A total of 90 studies were imported for screening, from which 9 papers met our final inclusion/exclusion criteria. The most common studies utilized in this review were retrospective chart reviews followed by case series. In total, there were 628 patients that suffered from gunshot wounds to the brachial plexus. Most patients underwent some form of delayed nerve repair consisting of neurolysis, end-to-end epineural repair, or graft repair with a sural or antebrachial cutaneous nerve graft. Several patients suffered from complications, with neuroma being the most common long-term complication that required reoperation.</p><p><strong>Conclusion: </strong>The optimal timing for surgeries involving BPIs should be determined after examining the level of nerve damage, associated injuries, operative risks, and electrophysiological workup for indications of spontaneous regeneration. Early surgical interventions were indicated for patients presenting with associated vascular or thoracic injuries, compressive masses, and nerve transection by sharp instruments in most selected papers.</p>","PeriodicalId":7358,"journal":{"name":"Advances in Orthopedics","volume":"2024 ","pages":"7708192"},"PeriodicalIF":1.2,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142152979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}