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Exploring the Impact of Preoperative Laboratory Values on Short-Term Outcomes in Complex Carpal Tunnel Decompression Surgery.
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-22 eCollection Date: 2025-01-01 DOI: 10.1155/aort/8494043
Anitesh Bajaj, Rushmin Khazanchi, Rohan M Shah, Joshua P Weissman, Nishanth S Sadagopan, Arun K Gosain

Background: The present study analyzes the effects of preoperative serum albumin, hematocrit, and creatinine on postoperative outcomes in patients undergoing carpal tunnel decompression surgery. Methods: The American College of Surgeons National Quality Improvement Program (NSQIP) database was queried from 2011 to 2020. Albumin, hematocrit, and creatinine were collected for each patient, alongside covariates. Outcomes included 30-day medical complications, 30-day wound complications, return to the operating room, nonhome discharge, and extended postoperative length of stay. Bivariate t-tests and multivariate logistic regressions were conducted. For any outcome-laboratory value pairs with significance on regression, area under the receiver operating characteristic curves (AUC) were constructed. Results: A total of 1440 patients with albumin, 3138 patients with hematocrit, and 3159 patients with creatinine levels were identified. Increased serum albumin was associated with lower odds of medical complications (aOR: 0.479, p=0.035). An overall cohort cutoff of ≤ 3.5 g/dL (AUC: 0.79, p < 0.001) was predictive of medical complications. On multivariate logistic regression, increased hematocrit reduced the odds of medical complications (aOR: 0.889, p < 0.001). Predictive hematocrit cutoffs of ≤ 39.7% (AUC: 0.77, p < 0.001) and ≤ 36.6% (AUC: 0.74, p < 0.001) were identified for medical complications amongst male and female patients, respectively. Similarly, increased serum creatinine was associated with greater odds of medical complications (aOR: 1.684, p=0.006). Creatinine cutoffs of ≥ 1.2 mg/dL (AUC: 0.58, p=0.033) and ≥ 1.0 mg/dL (AUC: 0.59, p=0.039) were identified for medical complications amongst male and female patients, respectively. Conclusions: Multiple preoperative serum values were predictive of postoperative medical complications, and laboratory value thresholds were identified in this carpal tunnel decompression cohort to aid in risk stratification.

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引用次数: 0
Impact of Weather and Holidays on Orthopedic Emergency Room Crowding, Fractures, and Polytraumas in a Third-Level Referral Trauma Center in Europe.
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-20 eCollection Date: 2025-01-01 DOI: 10.1155/aort/2970626
Lorenzo Andreani, Edoardo Ipponi, Francesco Pecchia, Giorgio Balestrieri, Edoardo Tosi, Stefano Marchetti, Paolo Domenico Parchi

Background: Orthopedic trauma is a significant component of emergency department workloads worldwide. The relationship between weather conditions and injury rates is controversial in modern literature. Even less has been written to investigate bank holidays' influence on contusions, dislocations, fractures, and even polytrauma. Our study aimed to assess whether meteorological factors and national holidays could vary the workloads in the orthopedic ER of a European third-level trauma center. Materials and Methods: Our study consisted of a review of all the patients who underwent orthopedic evaluations in our institution's orthopedic emergency room between 2019 and 2023. Days were divided depending on weather (cloudy or sunny vs. rainy or stormy), day type (regular working days vs. national public holidays vs. Saturdays and Sundays), and presence or absence of COVID-19 restrictions. We also recorded the temperatures of each day. Cases were subdivided into three groups: cases without significant injuries (Group A), cases with isolated bone fractures, major tears or articular dislocations (Group B1), and polytrauma (Group B2). Results: Higher temperatures were associated with a significant increase in overall ER visits, isolated injuries, and polytrauma. Sunny or cloudy days had a significantly higher number of patients with all injury types compared to rainy or stormy days. Weekends saw a significant decrease in overall admissions and isolated injuries but a higher rate of polytrauma compared to weekdays. National holidays had a significantly lower number of admissions for all injury types compared to weekdays. Restrictions due to the pandemic significantly reduced overall ER visits. Conclusion: Temperatures, meteorological factors, and national holidays could vary the workloads in the orthopedic ER of a European third-level trauma center.

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引用次数: 0
ChatGPT is an Unreliable Source of Peer-Reviewed Information for Common Total Knee and Hip Arthroplasty Patient Questions. ChatGPT是一个不可靠的同行评议的信息来源,常见的全膝关节和髋关节置换术患者的问题。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.1155/aort/5534704
Jonathan D Schwartzman, M Kareem Shaath, Matthew S Kerr, Cody C Green, George J Haidukewych
<p><p><b>Background:</b> Advances in artificial intelligence (AI), machine learning, and publicly accessible language model tools such as ChatGPT-3.5 continue to shape the landscape of modern medicine and patient education. ChatGPT's open access (OA), instant, human-sounding interface capable of carrying discussion on myriad topics makes it a potentially useful resource for patients seeking medical advice. As it pertains to orthopedic surgery, ChatGPT may become a source to answer common preoperative questions regarding total knee arthroplasty (TKA) and total hip arthroplasty (THA). Since ChatGPT can utilize the peer-reviewed literature to source its responses, this study seeks to characterize the validity of its responses to common TKA and THA questions and characterize the peer-reviewed literature that it uses to formulate its responses. <b>Methods:</b> Preoperative TKA and THA questions were formulated by fellowship-trained adult reconstruction surgeons based on common questions posed by patients in the clinical setting. Questions were inputted into ChatGPT with the initial request of using solely the peer-reviewed literature to generate its responses. The validity of each response was rated on a Likert scale by the fellowship-trained surgeons, and the sources utilized were characterized in terms of accuracy of comparison to existing publications, publication date, study design, level of evidence, journal of publication, journal impact factor based on the clarivate analytics factor tool, journal OA status, and whether the journal is based in the United States. <b>Results:</b> A total of 109 sources were cited by ChatGPT in its answers to 17 questions regarding TKA procedures and 16 THA procedures. Thirty-nine sources (36%) were deemed accurate or able to be directly traced to an existing publication. Of these, seven (18%) were identified as duplicates, yielding a total of 32 unique sources that were identified as accurate and further characterized. The most common characteristics of these sources included dates of publication between 2011 and 2015 (10), publication in The Journal of Bone and Joint Surgery (13), journal impact factors between 5.1 and 10.0 (17), internationally based journals (17), and journals that are not OA (28). The most common study designs were retrospective cohort studies and case series (seven each). The level of evidence was broadly distributed between Levels I, III, and IV (seven each). The averages for the Likert scales for medical accuracy and completeness were 4.4/6 and 1.92/3, respectively. <b>Conclusions:</b> Investigation into ChatGPT's response quality and use of peer-reviewed sources when prompted with archetypal pre-TKA and pre-THA questions found ChatGPT to provide mostly reliable responses based on fellowship-trained orthopedic surgeon review of 4.4/6 for accuracy and 1.92/3 for completeness despite a 64.22% rate of citing inaccurate references. This study suggests that until ChatGPT is proven to be a reliab
背景:人工智能(AI)、机器学习和可公开访问的语言模型工具(如ChatGPT-3.5)的进步继续塑造现代医学和患者教育的格局。ChatGPT的开放访问(OA)、即时、人性化的界面能够就无数主题进行讨论,这使其成为寻求医疗建议的患者的潜在有用资源。由于它与骨科手术有关,ChatGPT可能成为解答全膝关节置换术(TKA)和全髋关节置换术(THA)术前常见问题的来源。由于ChatGPT可以利用同行评议的文献来获取其回答,因此本研究试图表征其对常见TKA和THA问题的回答的有效性,并表征其用于制定其回答的同行评议文献。方法:术前TKA和THA的问题是由研究员培训的成人重建外科医生根据患者在临床环境中提出的常见问题制定的。问题被输入到ChatGPT中,最初的要求是仅使用同行评审的文献来生成答案。每个回答的有效性由接受过奖学金培训的外科医生用李克特量表进行评分,并根据与现有出版物比较的准确性、出版日期、研究设计、证据水平、出版期刊、基于clarivate分析因子工具的期刊影响因子、期刊OA状态以及该期刊是否在美国进行特征描述。结果:ChatGPT在回答TKA程序的17个问题和THA程序的16个问题时共引用了109个来源。39个来源(36%)被认为是准确的或能够直接追溯到现有出版物。其中,7个(18%)被鉴定为重复,总共产生32个被鉴定为准确并进一步表征的独特来源。这些来源最常见的特征包括发表日期在2011年至2015年之间(10),发表于The Journal of Bone and Joint Surgery(13),期刊影响因子在5.1至10.0之间(17),国际期刊(17)和非OA期刊(28)。最常见的研究设计是回顾性队列研究和病例系列研究(各7例)。证据水平大致分布在I级、III级和IV级之间(各7个)。Likert量表的医疗准确性和完整性的平均值分别为4.4/6和1.92/3。结论:对ChatGPT的回答质量和使用同行评议的资料进行的调查发现,尽管引用不准确参考文献的比例为64.22%,但ChatGPT提供的回答大部分是可靠的,其准确性为4.4/6,完整性为1.92/3。本研究提示,在ChatGPT被证明是有效信息和参考的可靠来源之前,患者在将tka前和THA问题导向该媒介时必须非常谨慎。
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引用次数: 0
Internal Fixation for Unstable Distal Ulnar Fractures by 2.7 mm Semitubular Hook Plate. 2.7 mm半管钩钢板内固定不稳定尺远端骨折。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-12-24 eCollection Date: 2024-01-01 DOI: 10.1155/aort/5663025
Mohamed I Abulsoud, Mohammed Elmarghany, Ahmed R Zakaria, Ehab A Alshal, Mohamed Moawad, Ehab A Elzahed, Mohamed F Elhalawany, Bahaa A Kornah

Objective: The purpose of this study is to investigate the outcomes of the use of a 2.7 mm semitubular hook plate for internal fixation of unstable metaphyseal ulnar fractures. Methods: Between January 2015 and July 2019, 30 consecutive patients with a recent unstable distal ulnar fracture were included in this prospective case series. All patients were subjected to follow-up with the time of union, range of motion, pain using a Visual Analog Scale (VAS), and radiological and functional outcome using the quick Disabilities of the Arm, Shoulder, and Hand (DASH) score and Mayo wrist score after 12 months. Results: The mean age of the patients was 45.3 ± 10 years. There were 18 males (60%) and 12 females (40%), and there were 16 patients associated with distal radius fractures (53.33%). According to the AO classification of distal ulnar fractures, 3 fractures were type A2.1 (10%), 9 were type A2.2 (30%), 8 fractures were type A2.3 (26.67%), and 10 fractures were type A3 (33.33%). All fractures have been united with a mean duration of 9 ± 1.4 weeks, the mean supination was 81.4° ± 3.5°, the mean pronation was 81.3° ± 4.5°, the mean flexion was = 71.7° ± 3.6°, and the mean extension was = 81.7° ± 3.4°. The mean VAS was 1.1 ± 1 points, the mean DASH score was 9.3 ± 5.6 points, and the mean Mayo wrist score was 88.5 ± 7.2 points; 17 patients were excellent (56.67%) and 10 patients were good (33.33%) while 3 patients had satisfactory outcome (10%). Conclusion: Using the 2.7 mm semitubular hook plate is a successful choice for internal fixation of unstable distal ulnar fractures isolated or associated with distal radius fractures with a favorable union time, functional outcome, and range of motion with minimal complications.

目的:本研究的目的是探讨2.7 mm半管钩钢板内固定不稳定干骺端尺侧骨折的效果。方法:2015年1月至2019年7月,连续30例近期不稳定尺远端骨折患者纳入前瞻性病例系列。所有患者均接受随访,随访时间包括愈合时间、活动范围、视觉模拟评分(VAS)疼痛,12个月后使用手臂、肩膀和手的快速残疾(DASH)评分和Mayo手腕评分进行放射学和功能预后。结果:患者平均年龄45.3±10岁。其中男性18例(60%),女性12例(40%),合并桡骨远端骨折16例(53.33%)。尺远端骨折AO分型中,A2.1型3例(10%),A2.2型9例(30%),A2.3型8例(26.67%),A3型10例(33.33%)。所有骨折均愈合,平均持续时间为9±1.4周,平均旋后81.4°±3.5°,平均旋前81.3°±4.5°,平均屈后71.7°±3.6°,平均伸后81.7°±3.4°。VAS平均1.1±1分,DASH平均9.3±5.6分,Mayo手腕平均88.5±7.2分;优17例(56.67%),良10例(33.33%),满意3例(10%)。结论:使用2.7 mm半管钩钢板内固定不稳定尺远端骨折或桡骨远端骨折是一种成功的选择,具有良好的愈合时间、功能预后、活动范围和最小的并发症。
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引用次数: 0
Addressing Knee Osteoarthritis Pathology Through Platelet-Rich Plasma Treatment: A Comprehensive Review. 通过富血小板血浆治疗解决膝关节骨性关节炎病理问题:全面回顾。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-11-19 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6551525
Silviu Valentin Vlad, Timea Claudia Ghitea, Felicia Manole, Alexandru-Stefan Nutiu, Alex Octavian Lupsa, Nicu Adrian Ghiurau, Florin Nicolae Blaga

Platelet-rich plasma (PRP) is gaining popularity across various medical fields, including orthopedics, for its potential in tissue regeneration and wound healing. As intra-articular treatments evolve, PRP has emerged as a promising option for managing knee osteoarthritis, meniscus, and ligament injuries. This review aims to provide an update on the current applications of PRP in treating knee osteoarthritis and its clinical implications in orthopedic and sports medicine. We reviewed 180 eligible studies, and our findings suggest that PRP injections significantly improve knee joint function compared to alternative treatments. The use of PRP across various medical fields has been growing in popularity recently. PRP is a biological product derived from the plasma portion of a patient's own blood, containing a higher concentration of platelets than normal. Its potential for tissue regeneration and wound healing has drawn significant attention from orthopedic surgeons, especially as intra-articular treatment options continue to evolve. The benefits of PRP in treating various osteoarticular conditions have sparked considerable interest within the orthopedic community, particularly for managing knee osteoarthritis, meniscus tears, and ligament injuries. This review aims to provide an updated overview of the current applications of PRP in the treatment of knee osteoarthritis and to offer clinical insights into its use in orthopedic and sports medicine practices. We reviewed 180 relevant titles and abstracts that met the inclusion criteria. Compared to other treatment options, PRP injections significantly enhance knee joint function.

富血小板血浆(PRP)因其在组织再生和伤口愈合方面的潜力,在包括骨科在内的各个医疗领域越来越受欢迎。随着关节内治疗方法的发展,PRP 已成为治疗膝关节骨关节炎、半月板和韧带损伤的一种有前途的选择。本综述旨在介绍 PRP 目前在治疗膝关节骨性关节炎方面的最新应用及其对骨科和运动医学的临床意义。我们回顾了 180 项符合条件的研究,结果表明,与其他治疗方法相比,PRP 注射能显著改善膝关节功能。近来,PRP 在各个医疗领域的应用日益普及。PRP 是一种生物制品,提取自患者自身血液中的血浆部分,其中血小板的浓度高于正常水平。它在组织再生和伤口愈合方面的潜力引起了整形外科医生的极大关注,特别是随着关节内治疗方法的不断发展。PRP 在治疗各种骨关节疾病方面的优势引发了骨科界的极大兴趣,尤其是在治疗膝关节骨关节炎、半月板撕裂和韧带损伤方面。本综述旨在概述目前 PRP 在膝关节骨关节炎治疗中的应用,并就其在骨科和运动医学实践中的应用提供临床见解。我们审查了 180 篇符合纳入标准的相关标题和摘要。与其他治疗方案相比,PRP注射能显著增强膝关节功能。
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引用次数: 0
Is Anterior Cruciate Ligament Reconstruction "Silva Technique" Equal to All-Inside Techniques? A Prospective Single-Center Study: An Alternative ACL All-Inside Reconstruction Technique Using a Tibial Tunnel and Bone Graft. 前交叉韧带重建 "Silva 技术 "是否等同于全内侧技术?一项前瞻性单中心研究:使用胫骨隧道和骨移植的另一种前交叉韧带全内重建技术。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-10-26 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2371242
Panagiotis Karampinas, John Vlamis, Athanasios Galanis, Michail Vavourakis, Evangelos Sakellariou, Iordanis Varsamos, Ioannis Spyrou, Spiros Pneumaticos

Background: The development of less invasive all-inside techniques regarding anterior cruciate ligament (ACL) reconstruction surgery has been associated with various advantages, including fewer complications and reduced postoperative pain. Silva et al. described a quadruple semitendinosus graft construct and suspensory button fixation for ACL reconstruction as an alternative technique. At the end of this technique, the tibial tunnel is filled with a bone autograft plug. This paper aims to examine the incorporation of the autograft and thus evaluate whether the "Silva technique" provides the same benefits as all-inside techniques. Methods: A prospective study assessed 31 patients undergoing ACL reconstruction surgery using the "Silva technique." The cases involved in the study were skeletally mature patients with no previous history of ACL surgery or multiligamentous instability. All patients followed the same rehabilitation program and were examined at three standardized follow-up visits: 4 months, 8 months, and 1 year postoperatively. Tegner-Lysholm knee score (TLKS), visual analog score (VAS) for pain, and the IKDC subjective knee score were completed at every visit. A knee MRI scan was performed at every scheduled visit to assess bone graft incorporation and remodeling. Results: TLKS scores revealed a considerable improvement compared to preoperative figures, from 57.2 points preoperatively to an average of 99.4 at the 12-month follow-up (p < 0.0001). VAS scores were substantially ameliorated after the operation and until the second follow-up visit, from 5 before surgery to zero 8 months after the operation, with no noteworthy alterations afterward (p < 0.0001). IKDC subjective knee score outcomes were found to have increased at the last follow-up, from 59.3 prior to surgery to 99.8 12 months postoperatively (p < 0.0001). Regarding the MRI features of the bone autograft, the tibial tunnel was entirely filled by bone formation at the last MRI scan, suggesting complete integration of the autograft in all patients. Conclusions: Bone autograft employed to seal the tibial tunnel was completely incorporated in all cases 1 year postoperatively. The "Silva technique" appears to feature all the avails of all-inside techniques, whilst it seems to be simpler and easier than them after the surgeon is familiarized with its particular aspects. It is a robust option in orthopedic surgeons' arsenal. However, further large-scale pertinent research is requisite to confirm the findings of this study.

背景:前交叉韧带(ACL)重建手术采用创伤较小的全内侧技术,具有减少并发症和减轻术后疼痛等多种优势。Silva 等人描述了一种用于前交叉韧带重建的四重半腱肌移植物构建和悬吊扣固定替代技术。在该技术的最后,胫骨隧道被自体骨移植塞填满。本文旨在研究自体移植物的植入情况,从而评估 "席尔瓦技术 "是否与全内侧技术具有相同的优势。研究方法一项前瞻性研究评估了31名使用 "席尔瓦技术 "进行前交叉韧带重建手术的患者。参与研究的病例均为骨骼发育成熟的患者,既往无前交叉韧带手术史或多韧带不稳定史。所有患者都接受了相同的康复计划,并在三次标准化随访中接受了检查:术后 4 个月、8 个月和 1 年。每次随访都要完成 Tegner-Lysholm 膝关节评分(TLKS)、疼痛视觉模拟评分(VAS)和 IKDC 膝关节主观评分。每次预约就诊时都进行膝关节核磁共振扫描,以评估植骨融合和重塑情况。结果TLKS 评分与术前相比有了显著改善,从术前的 57.2 分提高到 12 个月随访时的平均 99.4 分(P P P P 结论):在所有病例中,术后 1 年用于封闭胫骨隧道的骨自体移植物都完全融入了胫骨隧道。Silva技术 "似乎具有全内技术的所有优点,但在外科医生熟悉其特殊方面后,它似乎比全内技术更简单、更容易。在骨科医生的武器库中,这是一个强有力的选择。不过,要证实这项研究的结果,还需要进一步开展大规模的相关研究。
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引用次数: 0
Implant Survival of an Uncemented Modular Femoral Implant in Patients With Severe Femoral Bone Loss and 2-Stage Hip Revision. 非骨水泥模块化股骨假体在股骨头严重缺失和两期髋关节翻修患者中的植入存活率。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI: 10.1155/2024/6158822
Sebastian Winther, Naima Elsayed, Karen Dyreborg, Elinborg Mortensen, Michael M Petersen, Jens Stürup, Nikolaj S Winther

Background and Purpose: Revision total hip arthroplasty (rTHA) is a challenging procedure especially in the presence of severe bone loss where implant fixation is compromised. The aim of this study was to evaluate implant survival, clinical outcome, and midterm results in a group of complex patients after femoral revision using an uncemented modular implant design. Patients and Methods: We performed a retrospective study including 100 patients (101 hips) treated with revision THA using an uncemented modular implant design. We identified 51 hips as Paprosky types I-II and 50 hips as Paprosky III-IV bone defects. We reviewed operative reports and radiographs. Patients underwent a clinical examination to assess the Harris Hip Score (HHS) and completed patient-reported outcome measures (PROM), including the Oxford Hip Score (OHS) and the EQ-5D Visual Analog Scale (VAS). Minimum follow-up was 2 years (average, 5.8 years; range, 2.0-9.4 years). Results: Among the cases, 46 hips were revised for infection in a 2-stage procedure and 44 hips for aseptic loosening. 11 hips had periprosthetic fractures of Vancouver type B2 or B3. A total of 5 hips required revision with removal of the femoral implant and 11 patients experienced complications resulting in fracture (n = 1), dislocation (n = 10), and soft tissue revision (n = 1). The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%). All hips had radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Additionally, 80% showed radiographic evidence of restoration of proximal femoral bone. Mean HHS was 78. Conclusion: In complex cases of revision THA, using a modular revision femoral system yielded promising results. The 5-year implant survival estimated by Kaplan-Meier survival analysis was 95% (95%-CI: 91%-99%), with all hips demonstrating radiographic evidence of osseointegration and no one with subsidence greater than 5 mm. Notably 80% showed radiographic evidence of restoration of proximal femoral bone.

背景和目的:翻修全髋关节置换术(rTHA)是一项具有挑战性的手术,尤其是在骨质严重流失、植入物固定受到影响的情况下。本研究旨在评估一组使用非骨水泥模块化植入物设计的股骨翻修术后复杂患者的植入物存活率、临床效果和中期结果。患者和方法:我们进行了一项回顾性研究,包括使用非骨水泥模块化植入物设计进行翻修性 THA 治疗的 100 名患者(101 个髋关节)。我们将 51 个髋关节鉴定为 Paprosky I-II 型骨缺损,50 个髋关节鉴定为 Paprosky III-IV 型骨缺损。我们审查了手术报告和X光片。患者接受了临床检查以评估哈里斯髋关节评分(HHS),并完成了患者报告结果测量(PROM),包括牛津髋关节评分(OHS)和EQ-5D视觉模拟量表(VAS)。最少随访 2 年(平均 5.8 年;范围 2.0-9.4 年)。结果:在这些病例中,46个髋关节因感染进行了两阶段手术,44个髋关节因无菌性松动进行了翻修。11个髋关节发生了温哥华B2或B3型假体周围骨折。共有5个髋关节需要通过移除股骨假体进行翻修,11名患者出现并发症,导致骨折(1例)、脱位(10例)和软组织翻修(1例)。根据 Kaplan-Meier 生存分析估计,植入物的 5 年存活率为 95%(95%-CI:91%-99%)。所有髋关节都有骨结合的影像学证据,没有一个髋关节下沉超过 5 毫米。此外,80%的患者有股骨近端骨质恢复的影像学证据。平均 HHS 为 78。结论:在复杂的翻修THA病例中,使用模块化翻修股骨系统取得了很好的效果。通过Kaplan-Meier存活率分析估计,植入物的5年存活率为95%(95%-CI:91%-99%),所有髋关节都有骨整合的影像学证据,没有一个髋关节下沉超过5毫米。值得注意的是,80%的人都有股骨近端骨质恢复的影像学证据。
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引用次数: 0
Regular Nonsteroidal Anti-Inflammatory Drug Use Increases Stress Fracture Risk in the General Population: A Retrospective Case-Control Study. 经常服用非甾体抗炎药会增加普通人群应力性骨折的风险:一项回顾性病例对照研究。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-10-12 eCollection Date: 2024-01-01 DOI: 10.1155/2024/7933520
Alexandra Ciuciu, Christopher Mulholland, Michael A Bozzi, Chris C Frymoyer, Leonardo Cavinatto, David Yaron, Marc I Harwood, Jeremy D Close, Christopher J Mehallo, Ryan E Tomlinson

Previous studies have shown that the use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased stress fracture risk. This phenomenon has been studied predominantly in high-activity individuals, so data regarding the general population are limited despite the substantial economic and resource burden of stress fracture injuries within the general US population. Furthermore, our preclinical studies demonstrate that regular use of NSAIDs also diminishes the intrinsic ability of bone to resist fracture. To determine the association of regular NSAID use with stress fractures in the general population, we surveyed subjects presenting with either stress fracture or uncomplicated ankle sprain to assess their use of NSAIDs over the three months before their injury. We hypothesized that subjects with stress fractures would have increased regular NSAID usage as compared to controls. Subjects diagnosed with a stress fracture (n = 56) and subjects with uncomplicated ankle sprains (n = 51; control) were surveyed about their NSAID use at the time of their diagnosis and in the previous three months using a questionnaire based on the National Health and Nutrition Examination Survey (NHANES). Subjects were surveyed in person on the day of their injury diagnosis or by phone within 30 days of their diagnosis. Fisher's exact test was used to determine significant differences in NSAID usage between stress fracture and control subjects. Subjects diagnosed with stress fractures had a statistically significant increase in both current use (p=0.03) and regular use (p=0.04) of ibuprofen/naproxen/celecoxib as compared to control subjects. There were no significant differences in the use of aspirin, acetaminophen, or prescription medications containing acetaminophen between groups. Consistent with previous clinical reports, we observed a strong correlation between regular ibuprofen/naproxen/celecoxib use and stress fracture incidence in the general population. These results indicate that patients at high risk of stress fracture should avoid regular use of ibuprofen, naproxen, or celecoxib.

以往的研究表明,使用非甾体抗炎药(NSAIDs)会增加应力性骨折的风险。对这一现象的研究主要针对活动量大的人群,因此,尽管应力性骨折对美国普通人群造成了巨大的经济和资源负担,但有关普通人群的数据却很有限。此外,我们的临床前研究表明,经常使用非甾体抗炎药也会降低骨骼抵抗骨折的内在能力。为了确定在普通人群中定期使用非甾体抗炎药与应力性骨折的关系,我们对出现应力性骨折或无并发症踝关节扭伤的受试者进行了调查,以评估他们在受伤前三个月内使用非甾体抗炎药的情况。我们假设,与对照组相比,应力性骨折患者会增加非甾体抗炎药的常规使用。我们使用基于美国国家健康与营养调查(NHANES)的调查问卷,对确诊为应力性骨折的受试者(n = 56)和无并发症踝关节扭伤的受试者(n = 51;对照组)在确诊时及之前三个月内使用非甾体抗炎药的情况进行了调查。受试者在确诊受伤当天亲自接受调查,或在确诊后 30 天内通过电话接受调查。费雪精确检验用于确定应力性骨折受试者与对照组受试者在非甾体抗炎药使用方面的显著差异。与对照组受试者相比,确诊为应力性骨折的受试者在布洛芬/那普生/来曲昔布的当前使用量(p=0.03)和定期使用量(p=0.04)方面均有统计学意义上的显著增加。各组之间在使用阿司匹林、对乙酰氨基酚或含有对乙酰氨基酚的处方药方面没有明显差异。与之前的临床报告一致,我们观察到在普通人群中,定期使用布洛芬/萘普生/西来昔布与应力性骨折的发生率之间存在很强的相关性。这些结果表明,应力性骨折高危患者应避免经常使用布洛芬、萘普生或塞来昔布。
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引用次数: 0
From Etiology to Intervention: A Holistic Review of Bunion Pathophysiology and Care. 从病因到干预:拇趾外翻病理生理学和护理的整体回顾。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-10-11 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9910410
Danielle Barnes, Paige Matijasich, Aidan Maxwell, David Yatsonsky, Audrey Ballard, Nabil Ebraheim, Osama Elattar

In this review paper, we present the common etiology, presentation, diagnosis, and management of the following three common bunion formations: dorsal bunion, tailor's bunion, and hallux valgus (HV). Bunions are common pathologies that present to a variety of clinics, so it is important for providers to have a base understanding of these in order to provide the best care to patients. Many of these bunion formations have a variety of causes which allow providers to manage them before surgical intervention is required. The aim of this review paper is to bring attention and expanded insight on these common bunion presentations in order to minimize morbidity early on. The information provided in this review will allow both primary care and subspecialty physicians with the knowledge to accurately diagnose and optimally manage these bony deformities of the lower extremity.

在这篇综述论文中,我们将介绍以下三种常见拇外翻的病因、表现、诊断和治疗方法:足背外翻、足尾外翻和足外翻(HV)。拇外翻是常见的病症,会出现在不同的诊所,因此医疗人员必须对这些病症有基本的了解,才能为患者提供最佳的治疗。许多拇外翻形成的原因多种多样,因此医疗服务提供者可以在需要手术干预之前对其进行处理。本综述旨在引起人们对这些常见拇外翻表现的关注,并扩大对这些表现的认识,以便在早期将发病率降至最低。本综述提供的信息将使初级保健医生和亚专科医生掌握准确诊断和最佳处理这些下肢骨性畸形的知识。
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引用次数: 0
Treatment of Brachial Plexus Injuries following Gunshot Injuries: A Systematic Review. 枪伤后臂丛神经损伤的治疗:系统回顾。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1155/2024/7708192
Rohun Gupta, Isabel Herzog, Lauren Phung, Jacquelyn Roth, Joseph Weisberger, Margaret Luthringer, Edward S Lee, Ashley Ignatiuk

Introduction: Brachial plexus injuries (BPI) from gunshot injuries are uncommon but usually severe and can cause chronic pain, loss of function, and permanent nerve damage. Multiple surgical techniques including neurolysis, end-to-end suture repair, and graft repair have been described for the treatment of these injuries. However, surgical indication, timing, and technique for these injuries remain controversial. This systematic review aims to investigate the treatment modalities for patients with BPI due to gunshot-related injuries.

Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) methodology was employed for this review. PubMed, Cochrane Reviews, Embase, and CINAHL databases were included. The following keywords constituted our search criteria: gun-shot-wounds, brachial plexus, traum, and management.

Results: A total of 90 studies were imported for screening, from which 9 papers met our final inclusion/exclusion criteria. The most common studies utilized in this review were retrospective chart reviews followed by case series. In total, there were 628 patients that suffered from gunshot wounds to the brachial plexus. Most patients underwent some form of delayed nerve repair consisting of neurolysis, end-to-end epineural repair, or graft repair with a sural or antebrachial cutaneous nerve graft. Several patients suffered from complications, with neuroma being the most common long-term complication that required reoperation.

Conclusion: The optimal timing for surgeries involving BPIs should be determined after examining the level of nerve damage, associated injuries, operative risks, and electrophysiological workup for indications of spontaneous regeneration. Early surgical interventions were indicated for patients presenting with associated vascular or thoracic injuries, compressive masses, and nerve transection by sharp instruments in most selected papers.

导言:枪伤造成的臂丛神经损伤(BPI)并不常见,但通常很严重,可导致慢性疼痛、功能丧失和永久性神经损伤。已有多种手术技术用于治疗此类损伤,包括神经切除术、端对端缝合修复术和移植修复术。然而,这些损伤的手术指征、时机和技术仍存在争议。本系统性综述旨在研究枪伤导致的 BPI 患者的治疗方法:本综述采用了系统综述和元分析首选报告项目(PRISMA)方法。PubMed、Cochrane Reviews、Embase 和 CINAHL 数据库被纳入其中。搜索标准包括以下关键词:枪伤、臂丛神经、创伤∗和管理:结果:我们共筛选出 90 篇研究,其中 9 篇符合我们最终的纳入/排除标准。本综述中最常见的研究是回顾性图表综述,其次是病例系列。共有 628 名患者的臂丛神经受到枪伤。大多数患者都接受了某种形式的延迟神经修复,包括神经切除术、端对端外膜神经修复术或用硬膜或肱前皮神经移植修复术。一些患者出现了并发症,神经瘤是最常见的长期并发症,需要再次手术:结论:BPI 手术的最佳时机应在检查神经损伤程度、相关损伤、手术风险和电生理检查是否有自发再生迹象后确定。在大多数选定的论文中,对于伴有血管或胸部损伤、压迫性肿块和锐器造成神经横断的患者,应尽早进行手术干预。
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引用次数: 0
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Advances in Orthopedics
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