Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study.

IF 5.3 3区 医学 Q1 PSYCHIATRY General Psychiatry Pub Date : 2023-01-20 eCollection Date: 2023-01-01 DOI:10.1136/gpsych-2022-100908
Mohammed Y Khanji, George Collett, Thomas Godec, Carmela Maniero, Sher May Ng, Imrana Siddiqui, Jaya Gupta, Vikas Kapil, Ajay Gupta
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Abstract

Background: One potential modifiable factor to improve the mental health of healthcare professionals (HCPs) during the pandemic is lifestyle.

Aims: This study aimed to assess whether an improved lifestyle during the pandemic is associated with improved mental health symptoms and mental well-being in HCPs over time.

Methods: This was a cohort study involving an online survey distributed at two separate time points during the pandemic (baseline (July-September 2020) and follow-up (December 2020-March 2021)) to HCPs working in primary or secondary care in the UK. Both surveys assessed for major depressive disorder (MDD) (Patient Health Questionnaire-9 (PHQ-9)), generalised anxiety disorder (GAD) (Generalised Anxiety Disorder-7 (GAD-7)), mental well-being (Short Warwick-Edinburgh Mental Well-being Score (SWEMWBS)) and self-reported lifestyle change (compared with the start of the pandemic) on multiple domains. Cumulative scores were calculated to estimate overall lifestyle change compared with that before the pandemic (at both baseline and follow-up). At each time point, separate logistic regression models were constructed to relate the lifestyle change score with the presence of MDD, GAD and low mental well-being. Linear regression models were also developed relating the change in lifestyle scores from baseline to follow-up to changes in PHQ-9, GAD-7 and SWEMWBS scores.

Results: 613 HCPs completed both baseline assessment and follow-up assessment. Consistent significant cross-sectional associations between increased lifestyle change scores and a reduced risk of MDD, GAD and low mental well-being were observed at both baseline and follow-up. Over the study period, a whole unit increase in the change in novel scores (ie, improved overall lifestyle) over 4 months was inversely associated with changes in PHQ-9 (adjusted coefficient: -0.51, 95% confidence interval (CI): -0.73 to -0.30, p<0.001) and GAD-7 scores (adjusted coefficient: -0.32, 95% CI: -0.53 to -0.10, p=0.004) and positively associated with the change in SWEMWBS scores (adjusted coefficient: 0.37, 95% CI: 0.18 to 0.55, p<0.001).

Conclusions: Improved lifestyle over time is associated with improved mental health and mental well-being in HCPs during the pandemic. Improving lifestyle could be a recommended intervention for HCPs to help mitigate the mental health impact during the current and future pandemics.

Trial registration number: NCT04433260.

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在 COVID-19 大流行期间,生活方式的改善与英国医疗保健专业人员抑郁、焦虑和幸福感的长期改善有关:CoPE-HCP 队列研究的启示。
背景:目的:本研究旨在评估大流行期间生活方式的改善是否与大流行期间医护人员精神健康症状和精神健康状况的改善相关:这是一项队列研究,在大流行期间的两个不同时间点(基线(2020 年 7 月至 9 月)和随访(2020 年 12 月至 2021 年 3 月))对在英国初级或二级医疗机构工作的卫生保健人员进行在线调查。这两项调查评估了重度抑郁症(MDD)(患者健康问卷-9 (PHQ-9))、广泛性焦虑症(GAD)(广泛性焦虑症-7 (GAD-7))、精神健康(沃里克-爱丁堡精神健康简易评分 (SWEMWBS))和自我报告的生活方式改变(与大流行开始时相比)等多个方面。通过计算累计得分,可以估算出与大流行前相比(基线和随访)生活方式的总体变化。在每个时间点,我们分别建立了逻辑回归模型,将生活方式改变得分与是否存在 MDD、GAD 和低精神幸福感联系起来。此外,还建立了线性回归模型,将生活方式评分从基线到随访的变化与 PHQ-9、GAD-7 和 SWEMWBS 评分的变化联系起来:结果:613 名保健医生完成了基线评估和随访评估。在基线和随访中均观察到,生活方式改变得分的增加与 MDD、GAD 和低精神幸福感风险的降低之间存在一致的重要横断面关联。在研究期间,4 个月内新评分变化(即整体生活方式的改善)每增加一个整数单位与 PHQ-9 的变化成反比(调整系数:-0.51,95% 置信区间(CI):-0.73 至 -0.30,p 结论:随着时间的推移,生活方式的改善与 MDD、GAD 和低精神幸福感的风险降低有关:随着时间的推移,生活方式的改善与大流行期间卫生保健人员心理健康和心理幸福感的改善有关。在当前和未来的大流行期间,改善生活方式可作为建议对卫生保健人员采取的干预措施,以帮助减轻对心理健康的影响:NCT04433260.
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来源期刊
General Psychiatry
General Psychiatry 医学-精神病学
CiteScore
21.90
自引率
2.50%
发文量
848
期刊介绍: General Psychiatry (GPSYCH), an open-access journal established in 1959, has been a pioneer in disseminating leading psychiatry research. Addressing a global audience of psychiatrists and mental health professionals, the journal covers diverse topics and publishes original research, systematic reviews, meta-analyses, forums on topical issues, case reports, research methods in psychiatry, and a distinctive section on 'Biostatistics in Psychiatry'. The scope includes original articles on basic research, clinical research, community-based studies, and ecological studies, encompassing a broad spectrum of psychiatric interests.
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