Adherence to Continuous Positive Airway Pressure Therapy in Pediatric Patients with Obstructive Sleep Apnea: A Meta-Analysis.

IF 2.3 3区医学 Q2 HEALTH CARE SCIENCES & SERVICES Therapeutics and Clinical Risk Management Pub Date : 2023-01-01 DOI:10.2147/TCRM.S358737

Bundit Sawunyavisuth, Chetta Ngamjarus, Kittisak Sawanyawisuth

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引用次数: 1

Abstract

Introduction: Obstructive sleep apnea (OSA) is a public health problem that affects children. Although continuous positive airway pressure (CPAP) therapy is effective, the CPAP adherence rate in children is varied. This study aimed to evaluate the CPAP adherence rate and factors associated with CPAP adherence in children with OSA using a systematic review.

Methods: The inclusion criteria were observational studies conducted in children with OSA and assessed adherence of CPAP using objective evaluation. The literature search was performed in four databases. Meta-analysis using fixed-effect model was conducted to combine results among included studies.

Results: In all, 34 studies that evaluated adherence rate and predictors of CPAP adherence in children with OSA were included, representing 21,737 patients with an average adherence rate of 46.56%. There were 11 calculations of factors predictive of CPAP adherence: age, sex, ethnicity, body mass index, obesity, income, sleep efficiency, the apnea-hypopnea index (AHI), severity of OSA, residual AHI, and lowest oxygen saturation level. Three different factors were linked to children with adherence and non-adherence to CPAP: age, body mass index, and AHI.

Conclusion: The CPAP adherence rate in children with OSA was 46.56%. Young age, low body mass index, and high AHI were associated with acceptable CPAP adherence in children with OSA.

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阻塞性睡眠呼吸暂停患儿坚持持续气道正压治疗:一项荟萃分析。

梗阻性睡眠呼吸暂停(OSA)是影响儿童的公共卫生问题。虽然持续气道正压(CPAP)治疗是有效的，但儿童的CPAP依从率各不相同。本研究旨在通过系统回顾评估阻塞性睡眠呼吸暂停(OSA)患儿的CPAP依从率和与CPAP依从性相关的因素。方法:纳入标准为对OSA患儿进行观察性研究，采用客观评价法评估CPAP的依从性。在四个数据库中进行文献检索。采用固定效应模型进行meta分析，将纳入研究的结果合并。结果:总共纳入34项评估OSA患儿CPAP依从率和预测因素的研究，共21737例患者，平均依从率为46.56%。有11个预测CPAP依从性的因素计算:年龄、性别、种族、体重指数、肥胖、收入、睡眠效率、呼吸暂停低通气指数(AHI)、OSA严重程度、残留AHI和最低血氧饱和度。三个不同的因素与坚持和不坚持CPAP的儿童有关:年龄、体重指数和AHI。结论:OSA患儿CPAP依从率为46.56%。年龄小、低体重指数和高AHI与OSA患儿可接受的CPAP依从性相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-

CiteScore

4.80

自引率

3.60%

发文量

139

审稿时长

16 weeks

期刊介绍： Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.