A Systematic Approach of the Intrauterine Morphogenesis of the Human Palpebral Apparatus.

IF 1.6 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Organogenesis Pub Date : 2022-12-31 DOI:10.1080/15476278.2022.2066453

Octavian Munteanu, Florin-Mihail Filipoiu, Monica Mihaela Cirstoiu, Roxana Elena Bohiltea, Tiberiu Augustin Georgescu, Adrian Dumitru, Andra-Ioana Băloiu, Mihai-Alin Publik, Ioan-Andrei Petrescu

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Abstract

The human eyelid embodies a vast diversity of functions. Acting as a protective shield for the ocular apparatus and as a light regulator in the sight process, eyelids stand a fascinating - yet omitted - role in facial aesthetics, serving as a racial trait by which humankind succeeded to manifest heterogeneity as a species. These assumptions are precisely forecasted right from in-utero life through intricate processes of growth and cell differentiation. In the Department of Anatomy of "Carol Davila" University of Medicine and Pharmacy, we performed morphological assessments on 41 embryos and fetuses with gestational ages ranging from 6 to 29 weeks. This study aims to illustrate the morphogenesis of eyelids in human embryos and fetuses and highlight macroscopic features which could potentially have significant clinical implications in ophthalmic pathology.

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人眼睑器官宫内形态发生的系统研究。

人类的眼睑具有多种多样的功能。作为眼部器官的保护罩和视觉过程中的光调节器，眼睑在面部美学中扮演着一个迷人的——但被忽略的——角色，作为一种种族特征，人类成功地表现出作为一个物种的异质性。这些假设是通过复杂的生长和细胞分化过程在子宫内精确预测出来的。在“Carol Davila”医药大学解剖学系，我们对41例胎龄6 ~ 29周的胚胎和胎儿进行了形态学评估。本研究旨在阐明人类胚胎和胎儿眼睑的形态发生，并强调可能在眼科病理学中具有重要临床意义的宏观特征。

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来源期刊

Organogenesis BIOCHEMISTRY & MOLECULAR BIOLOGY-DEVELOPMENTAL BIOLOGY

CiteScore

4.10

自引率

4.30%

发文量

审稿时长

>12 weeks

期刊介绍： Organogenesis is a peer-reviewed journal, available in print and online, that publishes significant advances on all aspects of organ development. The journal covers organogenesis in all multi-cellular organisms and also includes research into tissue engineering, artificial organs and organ substitutes. The overriding criteria for publication in Organogenesis are originality, scientific merit and general interest. The audience of the journal consists primarily of researchers and advanced students of anatomy, developmental biology and tissue engineering. The emphasis of the journal is on experimental papers (full-length and brief communications), but it will also publish reviews, hypotheses and commentaries. The Editors encourage the submission of addenda, which are essentially auto-commentaries on significant research recently published elsewhere with additional insights, new interpretations or speculations on a relevant topic. If you have interesting data or an original hypothesis about organ development or artificial organs, please send a pre-submission inquiry to the Editor-in-Chief. You will normally receive a reply within days. All manuscripts will be subjected to peer review, and accepted manuscripts will be posted to the electronic site of the journal immediately and will appear in print at the earliest opportunity thereafter.