Early Weight-bearing Accelerates Regenerate Bone Mineralisation: A Pilot Study Comparing Two Post-operative Weight-bearing Protocols Following Intramedullary Limb Lengthening Using the Pixel Value Ratio.

IF 1 Q3 ORTHOPEDICS Strategies in Trauma and Limb Reconstruction Pub Date : 2022-09-01 DOI:10.5005/jp-journals-10080-1572

Anirejuoritse Bafor, Molly E Duncan, Christopher A Iobst

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引用次数: 2

Abstract

Introduction: Limb lengthening is increasingly accomplished by internal lengthening nails. Previous versions of the magnetic lengthening nails made from titanium alloy allowed limited weight-bearing. In contrast, the newer nails made of stainless steel allow increased weight-bearing. An objective comparison of the rate of healing of the regenerate bone based on the weight-bearing capabilities of these two types of lengthening nails has not been evaluated. The hypothesis for the study is that earlier commencement of full weight-bearing in patients treated with the stainless steel STRYDE^® nail will lead to faster healing of the regenerate bone during intramedullary limb lengthening compared with those treated with the titanium PRECICE^® nail.

Materials and methods: Thirty patients, divided into two groups of 15 each, underwent antegrade intramedullary lengthening of the femur using a magnetic lengthening nail between May 2017 and November 2020. The pixel value ratio (PVR) obtained from serial digital radiographs was used to quantitatively determine the regenerate bone's mineralisation rate. We compared the rate of healing of the regenerate bone in both groups of patients using the PVR.

Results: Patients treated with the STRYDE^® nail achieved unassisted full weight-bearing significantly earlier than patients treated with the PRECICE^® nail (12 weeks vs 17 weeks for STRYDE^® and PRECICE^® nail-lengthened patients, respectively, p = 0.003). There was no difference in the PVR between both groups of patients at the time of full weight-bearing (p = 0.0857). However, patients treated with the STRYDE® nail attained a PVR of 1 significantly earlier than those treated with the PRECICE^® nail (0.0317).

Conclusion: The STRYDE^® nail provides an earlier return of function and full weight-bearing compared with the PRECICE^® lengthening nail. Earlier commencement of weight-bearing ambulation leads to more rapid mineralisation of the regenerate bone in patients undergoing intramedullary limb lengthening.

How to cite this article: Bafor A, Duncan ME, Iobst CA, et al. Early Weight-bearing Accelerates Regenerate Bone Mineralisation: A Pilot Study Comparing Two Post-operative Weight-bearing Protocols Following Intramedullary Limb Lengthening Using the Pixel Value Ratio. Strategies Trauma Limb Reconstr 2022;17(3):148-152.

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早期负重加速再生骨矿化：使用像素值比率比较两种术后负重方案的初步研究。

简介：越来越多的肢体延长是通过内部延长指甲来完成的。以前的钛合金磁性加长钉允许有限的承重。相比之下，不锈钢制成的新型指甲可以增加承重。基于这两种类型的延长钉的承重能力对再生骨愈合率的客观比较尚未得到评估。该研究的假设是，与使用钛PRECISE®钉治疗的患者相比，使用不锈钢STRYDE®钉的患者在髓内肢体延长期间更早开始完全负重将导致再生骨更快愈合。材料和方法：30名患者，分为两组，每组15人，在2017年5月至2020年11月期间使用磁性延长钉进行股骨顺行髓内延长。从一系列数字射线照片中获得的像素值比（PVR）用于定量确定再生骨的矿化率。我们比较了使用PVR的两组患者的再生骨愈合率两组患者在完全负重时（p=0.0857）。然而，使用STRYDE®指甲治疗的患者的PVR显著早于使用PREICE®指甲治疗（0.0317）的患者。早期开始负重行走可使接受髓内肢体延长的患者再生骨更快矿化。如何引用这篇文章：Bavor A，Duncan ME，Iobst CA等人。早期负重加速再生骨矿化：一项使用像素值比率比较两种术后负重方案的初步研究。创伤肢体康复策略2022；17（3）:148-152。

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来源期刊

Strategies in Trauma and Limb Reconstruction Medicine-Orthopedics and Sports Medicine

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1.50

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0.00%

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期刊介绍： Strategies in Trauma and Limb Reconstruction is dedicated to surgeons, allied medical professionals and researchers in the field of orthopaedics and trauma. The scope of the journal is to discuss the fields of skeletal injury, and the complications thereof, congenital and acquired limb deformities and deficiencies, and orthopaedic-related infection, together with their surgical and non-surgical treatments. The journal publishes original articles, reviews, case reports, descriptions of new or recognised treatment techniques, forum discussions of clinical scenarios and relevant correspondence. It aims to provide a widely accessible source of useful information to practitioners in the field through the problem- or technique-based approach of published articles.