Fluid structure interaction analysis to stratify the behavior of different atheromatous carotid plaques.

IF 1.4 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Surgery Pub Date : 2023-02-01 DOI:10.23736/S0021-9509.22.12170-1

Maurizio Domanin, Lorenzo Bennati, Christian Vergara, Daniele Bissacco, Chiara Malloggi, Vincenzo Silani, Gianfranco Parati, Santi Trimarchi, Renato Casana

{"title":"Fluid structure interaction analysis to stratify the behavior of different atheromatous carotid plaques.","authors":"Maurizio Domanin, Lorenzo Bennati, Christian Vergara, Daniele Bissacco, Chiara Malloggi, Vincenzo Silani, Gianfranco Parati, Santi Trimarchi, Renato Casana","doi":"10.23736/S0021-9509.22.12170-1","DOIUrl":null,"url":null,"abstract":"Background: In asymptomatic carotid stenosis (ACS), different plaque types, i.e. lipidic (LP), fibrous (FP), and calcific (CP), could have different hemodynamic and structural behaviors.Methods: Different carotid plaques, reconstructed from medical imaging of ACS >70%, were analyzed by computing fluid structure interaction (FSI), modeling the spatial distribution of wall shear stresses (WSS), plaque displacements (D), von Mises stresses (VMS), and absorbed elastic energy (AEE) together with their maximum-in-space values at the systole (WSS<inf>syst</inf>, D<inf>syst</inf>, VMS<inf>syst</inf> and AEE<inf>syst</inf>).Results: WSS resulted significantly higher in CP, whereas D and VMS showed the highest values for LP. Regarding AEE<inf>syst</inf> stored by the plaques, LP absorbed in average 2320 J/m3, FP 408 J/m3 (470%) and CP 99 J/m3 (2240%), (P<0.01, P<0.01, and P<0.01, respectively).Conclusions: Depending upon their nature, plaques store different deformations and inner distributions of forces, thus potentially influencing their vulnerability.","PeriodicalId":50245,"journal":{"name":"Journal of Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.23736/S0021-9509.22.12170-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Background: In asymptomatic carotid stenosis (ACS), different plaque types, i.e. lipidic (LP), fibrous (FP), and calcific (CP), could have different hemodynamic and structural behaviors.

Methods: Different carotid plaques, reconstructed from medical imaging of ACS >70%, were analyzed by computing fluid structure interaction (FSI), modeling the spatial distribution of wall shear stresses (WSS), plaque displacements (D), von Mises stresses (VMS), and absorbed elastic energy (AEE) together with their maximum-in-space values at the systole (WSSsyst, Dsyst, VMSsyst and AEEsyst).

Results: WSS resulted significantly higher in CP, whereas D and VMS showed the highest values for LP. Regarding AEEsyst stored by the plaques, LP absorbed in average 2320 J/m³, FP 408 J/m³ (470%) and CP 99 J/m³ (2240%), (P<0.01, P<0.01, and P<0.01, respectively).

Conclusions: Depending upon their nature, plaques store different deformations and inner distributions of forces, thus potentially influencing their vulnerability.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

流体结构相互作用分析对不同动脉粥样斑块的行为进行分层。

背景:在无症状颈动脉狭窄(ACS)中，不同类型的斑块，即脂质斑块(LP)、纤维状斑块(FP)和钙化斑块(CP)，可能具有不同的血流动力学和结构行为。方法:根据ACS >70%的医学影像重建不同的颈动脉斑块，通过计算流体结构相互作用(FSI)，模拟壁面剪切应力(WSS)、斑块位移(D)、von Mises应力(VMS)和吸收弹性能(AEE)的空间分布及其在收缩期的最大空间值(WSSsyst、Dsyst、VMSsyst和AEEsyst)，对斑块进行分析。结果:WSS导致CP显著增高，而D和VMS显示LP最高。对于斑块储存的AEEsyst, LP平均吸收2320 J/m3, FP平均吸收408 J/m3 (470%)， CP平均吸收99 J/m3(2240%)。(结论:根据斑块的性质，斑块储存不同的变形和内部力分布，从而可能影响其易损性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Journal of Cardiovascular Surgery 医学-外科

CiteScore

2.50

自引率

7.10%

发文量

204

审稿时长

4-8 weeks

期刊介绍： The Journal of Cardiovascular Surgery publishes scientific papers on cardiac, thoracic and vascular surgery. Manuscripts may be submitted in the form of editorials, original articles, review articles, case reports, therapeutical notes, special articles and letters to the Editor. Manuscripts are expected to comply with the instructions to authors which conform to the Uniform Requirements for Manuscripts Submitted to Biomedical Editors by the International Committee of Medical Journal Editors (www.icmje.org). Articles not conforming to international standards will not be considered for acceptance.