A Descriptive Review of Cannabis sativa Patents for Cancer Treatment.

IF 2.5 4区 医学 Q3 ONCOLOGY Recent patents on anti-cancer drug discovery Pub Date : 2024-01-01 DOI:10.2174/1574892818666230213095717
Isabela Fernandes Pereira, Ana Maria Santos Oliveira, Anamaria Mendonça Santos, Denis de Melo Soares, Mairim Russo Serafini, Izabel Almeida Alves
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Abstract

Background: Cannabis use for tumor treatment has been explored in several areas, and its potential for tumor remission is currently being studied after the discovery of the endogenous cannabinoid.

Objective: The study aimed to conduct a critical patent review to identify and explore the latest advances and therapeutic strategies using Cannabis to treat cancer.

Methods: The research was carried out in the free and online database Espacenet, using the descriptors "cancer" and "Cannabis or cannabidiol" in the title or abstract. A total of 95 patents were identified for preliminary evaluation in the database. Six duplicate patents were excluded, 12 referring to traditional Chinese medicine and 36 with a title in disagreement with the scope of this review. In addition the final selection involved 21 patents that were in line with the objective of the study.

Results: As observed in the reading of patents, the interest of pharmaceutical industries and researchers and the development of new products to fight cancer have increased in recent years. The main cannabinoids present in the patents are tetrahydrocannabinol, cannabidiol, and hemp. Moreover, the patents were classified and the main applicant countries were the United States followed by Japan, with a higher filing rate in 2019 and, mainly by the industry.

Conclusion: In conclusion we can say that, the importance of parliamentary approval in the cultivation and investments that, in addition to bringing innovation to the industrial sector, enriches research in the area, contributing to the creation of new medicines.

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对用于癌症治疗的大麻专利的描述性回顾。
背景:在发现内源性大麻素之后,目前正在研究大麻用于治疗肿瘤的潜力:本研究旨在开展一项重要的专利综述,以确定和探索利用大麻治疗癌症的最新进展和治疗策略:研究在免费在线数据库 Espacenet 中进行,在标题或摘要中使用了 "癌症 "和 "大麻或大麻二酚 "描述符。数据库中共确定了 95 项专利进行初步评估。排除了 6 项重复专利、12 项涉及传统中药的专利和 36 项标题与本综述范围不符的专利。此外,最终选择了 21 项符合研究目标的专利:从专利阅读中可以看出,近年来制药业和研究人员对开发抗癌新产品的兴趣与日俱增。专利中主要的大麻素有四氢大麻酚、大麻二酚和大麻。此外,对专利进行了分类,主要申请国是美国,其次是日本,2019 年申请率较高,主要是工业界:总之,我们可以说,议会批准在种植和投资方面的重要性,除了为工业部门带来创新,还丰富了该领域的研究,有助于创造新的药物。
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来源期刊
CiteScore
4.50
自引率
7.10%
发文量
55
审稿时长
3 months
期刊介绍: Aims & Scope Recent Patents on Anti-Cancer Drug Discovery publishes review and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of anti-cancer drug discovery e.g. on novel bioactive compounds, analogs, targets & predictive biomarkers & drug efficacy biomarkers. The journal also publishes book reviews of eBooks and books on anti-cancer drug discovery. A selection of important and recent patents on anti-cancer drug discovery is also included in the journal. The journal is essential reading for all researchers involved in anti-cancer drug design and discovery. The journal also covers recent research (where patents have been registered) in fast emerging therapeutic areas/targets & therapeutic agents related to anti-cancer drug discovery.
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