Pretreatment hearing grades and hearing recovery outcomes after primary hyperbaric oxygen treatment in patients with idiopathic sudden sensorineural hearing loss.

IF 0.8 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Diving and hyperbaric medicine Pub Date : 2022-09-30 DOI:10.28920/dhm52.3.191-196

Andrijana Včeva, Željko Zubčić, Hrvoje Mihalj, Josip Maleš, Tihana Mendeš, Anamarija Šestak

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引用次数: 1

Abstract

Introduction: Previous studies suggest the effectiveness of hyperbaric oxygen treatment (HBOT) in idiopathic sudden sensorineural hearing loss (ISSNHL) but it is mostly used as an adjuvant and salvage treatment. This study evaluated the effect of primary HBOT according to pretreatment hearing grades and hearing recovery outcomes using modified Siegel's criteria in patients with ISSNHL.

Methods: Fifty-nine ISSNHL patients treated with only HBOT were included. A pure-tone audiogram was recorded before and after a course of HBOT (90 min at 203 kPa daily for 20 days). Using the modified Siegel's criteria, patients were divided into groups according to hearing threshold before and after treatment.

Results: Hearing thresholds were significantly lower after HBOT compared to pre-treatment values across all patients (P < 0.001) with a median value of recovery of 22.5 dB (interquartile range 12.5-33.7 dB). Significantly lower hearing threshold values were recorded at 500, 1,000, 2,000, and 4,000 Hz after treatment (P < 0.001). The greatest recovery was at 1,000 Hz, (change in median threshold = 32 dB) but without a significant difference compared to other frequencies (P = 0.10).

Conclusions: HBOT is a legitimate choice as the primary treatment for ISSNHL, especially if it is readily accessible, and if there are contraindications for corticosteroid therapy.

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特发性突发性感音神经性听力损失患者接受初级高压氧治疗后的预处理听力分级和听力恢复结果。

引言：先前的研究表明高压氧治疗（HBOT）对特发性突发性感音神经性听力损失（ISSNHL）有效，但它主要用作辅助和挽救治疗。本研究根据ISSNHL患者治疗前的听力等级和听力恢复结果，使用改良的Siegel标准评估了原发性HBOT的效果。方法：59例ISSNHL患者仅接受HBOT治疗。在一个疗程的HBOT之前和之后记录纯音听力图（在每天203kPa下90分钟，持续20天）。采用改良的西格尔标准，根据治疗前后的听力阈值将患者分为两组。结果：与治疗前相比，HBOT后所有患者的听力阈值均显著降低（P<0.001），恢复中值为22.5 dB（四分位间距为12.5-33.7 dB）。治疗后，在500、1000、2000和4000 Hz时记录到明显较低的听力阈值（P<0.001）。在1000 Hz时恢复最大（中位阈值变化=32dB），但与其他频率相比没有显著差异（P=0.010）。结论：HBOT是ISSNHL的主要治疗方法，特别是如果它很容易获得，以及是否有皮质类固醇治疗的禁忌症。

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来源期刊

Diving and hyperbaric medicine 医学-公共卫生、环境卫生与职业卫生

CiteScore

1.70

自引率

22.20%

发文量

审稿时长

>12 weeks

期刊介绍： Diving and Hyperbaric Medicine (DHM) is the combined journal of the South Pacific Underwater Medicine Society (SPUMS) and the European Underwater and Baromedical Society (EUBS). It seeks to publish papers of high quality on all aspects of diving and hyperbaric medicine of interest to diving medical professionals, physicians of all specialties, scientists, members of the diving and hyperbaric industries, and divers. Manuscripts must be offered exclusively to Diving and Hyperbaric Medicine, unless clearly authenticated copyright exemption accompaniesthe manuscript. All manuscripts will be subject to peer review. Accepted contributions will also be subject to editing.